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Clinical and Laboratory Factors Associated with Symptom Development in Asymptomatic COVID-19 Patients at the Time of Diagnosis

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초록

In preparation for the surge of coronavirus disease 2019 (COVID-19), it is crucial to allocate medical resources efficiently for distinguishing people who remain asymptomatic until the end of the disease. Between January 27, 2020, and April 21, 2020, 517 COVID-19 cases from 13 healthcare facilities in Gyeonggi province, Korea, were identified out of which the epidemiologic and clinical information of 66 asymptomatic patients at the time of diagnosis were analyzed retrospectively. An exposure-diagnosis interval within 7 days and abnormal aspartate aminotransferase levels were identified as characteristic symptom development in asymptomatic COVID-19 patients. If asymptomatic patients without these characteristics at the time of diagnosis could be differentiated early, more medical resources could be secured for mild or moderate cases in this COVID-19 surge.

Abstract

In preparation for the surge of coronavirus disease 2019 (COVID-19), it is crucial to allocate medical resources efficiently for distinguishing people who remain asymptomatic until the end of the disease. Between January 27, 2020, and April 21, 2020, 517 COVID-19 cases from 13 healthcare facilities in Gyeonggi province, Korea, were identified out of which the epidemiologic and clinical information of 66 asymptomatic patients at the time of diagnosis were analyzed retrospectively. An exposure-diagnosis interval within 7 days and abnormal aspartate aminotransferase levels were identified as characteristic symptom development in asymptomatic COVID-19 patients. If asymptomatic patients without these characteristics at the time of diagnosis could be differentiated early, more medical resources could be secured for mild or moderate cases in this COVID-19 surge.

참고문헌 (10)

  1. Zhu N, "A novel coronavirus from patients with pneumonia in China, 2019", N Engl J Med, 382, pp.727~733 (2020)
  2. Hodgson SH, "What defines an efficacious COVID-19 vaccine? A review of the challenges assessing the clinical efficacy of vaccines against SARSCoV-2", Lancet Infect Dis, 21, pp.e26~e35 (2021)
  3. Kang J, "South Korea's responses to stop the COVID-19pandemic", Am J Infect Control, 48, pp.1080~1086 (2020)
  4. Lee Yeji, "The Development and Operation of a Home Management System during the COVID-19 Pandemic: Experience of the Local Government Gyeonggi-do in Korea", Journal of Korean Medical Science, 36(19), pp.1~9 (2021), 대한의학회[DOI]
  5. Izcovich A, "Prognostic factors for severity and mortality in patients infected with COVID-19 : A systematic review", PLoS One, 15, pp.e0241955~ (2020)
  6. Wynants L, "Prediction models for diagnosis and prognosis of covid-19: systematic review and critical appraisal", BMJ, 369, pp.m1328~ (2020)
  7. Xie Y, "Epidemiologic, clinical, and laboratory findings of the COVID-19 in the current pandemic : systematic review and meta-analysis", BMC Infect Dis, 20, pp.640~ (2020)
  8. Wang Q, "Pattern of liver injury in adult patients with COVID-19 : a retrospective analysis of 105 patients", Mil Med Res, 7, pp.28~ (2020)
  9. Hao SR, "Liver enzyme elevation in coronavirus disease 2019 : a multicenter, retrospective, cross-sectional study", Am J Gastroenterol, 115, pp.1075~1083 (2020)
  10. Kang E, "Operating protocols of a community treatment center for isolation of patients with coronavirus disease, South Korea", Emerg Infect Dis, 26, pp.2329~2337 (2020)

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