본문 바로가기
KERD
논문KCI 등재

Should Breakthrough SARS-CoV-2 Infection Affect Our Confidence in the COVID-19 Vaccines?

Lamptey Emmanuel
대한감염학회 (The Korean Society Of Infectious Diseases)|2021.12|Infection and Chemotherapy|제53권 제4호|pp. 676-685|DOI 10.3947/ic.2021.0134

1

조회

0

다운로드

4

인용

0

참고문헌

키워드

ConfidenceVaccinesHesitancyCOVID-19 breakthroughs infections
주제분류내과학

초록

Coronavirus disease 2019 (COVID-19) vaccines have shown excellent clinical efficacy and effectiveness in real-world data. Although they are regarded as a means of ending the global pandemic, some individuals become infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) after immunization. This growing evidence or lack of effectiveness has led to vaccine refusal. This paper sought to help the public gain a deeper understanding of breakthrough events creating the positive perception that vaccines remain effective in ending the pandemic. Discussions vital for the general public’s active participation in vaccination are expressed to create confidence or provide a potential solution to the challenge of vaccine hesitancy.

Abstract

Coronavirus disease 2019 (COVID-19) vaccines have shown excellent clinical efficacy and effectiveness in real-world data. Although they are regarded as a means of ending the global pandemic, some individuals become infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) after immunization. This growing evidence or lack of effectiveness has led to vaccine refusal. This paper sought to help the public gain a deeper understanding of breakthrough events creating the positive perception that vaccines remain effective in ending the pandemic. Discussions vital for the general public’s active participation in vaccination are expressed to create confidence or provide a potential solution to the challenge of vaccine hesitancy.

참고문헌 (70)

  1. Wu D, "The SARS-CoV-2 outbreak : What we know", Int J Infect Dis, 94, pp.44~48 (2020)
  2. Day M, "Covid-19: four fifths of cases are asymptomatic, China figures indicate", BMJ, 369, pp.m1375~ (2020)
  3. Wang D, "Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China", JAMA, 323, pp.1061~1069 (2020)
  4. Guan WJ, "China Medical Treatment Expert Group for Covid-19. Clinical characteristics of coronavirus disease 2019 in China", N Engl J Med, 382, pp.1708~1720 (2020)
  5. Koyama T, "Variant analysis of SARS-CoV-2 genomes", Bull World Health Organ, 98, pp.495~504 (2020)
  6. "COVID-19: SARS-CoV-2 variant classifications and definitions"[URL]
  7. "COVID-19: Variants of concern and variants of interest"[URL]
  8. "“Immunity passports” in the context of COVID-19"[URL]
  9. Tillett RL, "Genomic evidence for reinfection with SARS-CoV-2 : a case study", Lancet Infect Dis, 21, pp.52~58 (2021)
  10. "COVID-19 breakthrough case investigations and reporting"[URL]
  11. "Parker-Pope T. Worried about breakthrough infections? Here’s how to navigate this phase of the pandemic"[URL]
  12. "COVID-19 vaccination"[URL]
  13. "Six important things to know about breakthrough infections"[URL]
  14. "Measles, mumps, and rubella (MMR) vaccination:What everyone should know"[URL]
  15. "Vaccine effectiveness: How well do flu vaccines work?"[URL]
  16. "The game is not yet over, and vaccines still matter: Lessons from a study on Israel’s COVID-19 vaccination"[URL]
  17. "COVID-19. Key things to know about COVID-19vaccines"[URL]
  18. "Breakthrough cases: Tracking disease infection after vaccination"[URL]
  19. "What are the new top 5 COVID symptoms?"[URL]
  20. Thompson MG, "Prevention and attenuation of Covid-19 with the BNT162b2 and mRNA-1273 vaccines", N Engl J Med, 385, pp.320~329 (2021)
  21. Levine-Tiefenbrun M, "Initial report of decreased SARS-CoV-2 viral load after inoculation with the BNT162b2 vaccine", Nat Med, 27, pp.790~792 (2021)
  22. Griffin JB, "SARS-CoV-2infections and hospitalizations among persons aged ≥16 years, by vaccination status-Los Angeles county, California, May 1-July 25, 2021", MMWR Morb Mortal Wkly Rep, 70, pp.1170~1176 (2021)
  23. "One in 5,000. The real chances of a breakthrough infection"[URL]
  24. "COVID-19. Delta variant"[URL]
  25. "Help slow the spread of COVID-19"[URL]
  26. Antonelli M, "Risk factors and disease profile of post-vaccination SARS-CoV-2 infection in UK users of the COVID Symptom Study app: a prospective, community-based, nested, case-control study", Lancet Infect Dis (2021)
  27. "Here’s how well COVID-19 vaccines work against the Delta variant"[URL]
  28. "Coronavirus breakthrough infections: Factors which make it easier for someone to get COVID-19 after vaccination"[URL]
  29. "If you got the Johnson & Johnson vaccine, do you need another dose?"[URL]
  30. "Severe breakthrough infections remain very rare, despite rising concerns"[URL]
  31. Barouch DH, "Durable humoral and cellular immune responses 8 months after Ad26.COV2.S vaccination", N Engl J Med, 385, pp.951~953 (2021)
  32. Brosh-Nissimov T, "BNT162b2vaccine breakthrough : clinical characteristics of 152 fully vaccinated hospitalized COVID-19 patients in Israel", Clin Microbiol Infect, 27, pp.1652~1657 (2021)
  33. "How will COVID vaccines work on compromised immune systems? Here’s what we know"[URL]
  34. "COVID-19 vaccines may protect many, but not all, people with suppressed immune systems"[URL]
  35. "Here’s what you need to know about COVID-19 breakthrough infections"[URL]
  36. "Coronavirus vaccines may be slightly less effective for women than men, emerging research suggests"[URL]
  37. Polack FP, "Safety and efficacy of the BNT162b2 mRNA Covid-19vaccine", N Engl J Med, pp.3832603~3832615 (2020)
  38. CDC COVID-19 Vaccine Breakthrough Case Investigations Team, "COVID-19 vaccine breakthrough infections reported to CDC - United States, January 1-April 30, 2021", MMWR Morb Mortal Wkly Rep, 70, pp.792~793 (2021)
  39. "The coronavirus affects women and men differently - Learning how may help stop the pandemic"[URL]
  40. Dolgin E, "COVID vaccine immunity is waning - how much does that matter?", Nature, 597, pp.606~607 (2021)
  41. Naaber P, "Dynamics of antibody response to BNT162b2 vaccine after six months : a longitudinal prospective study", Lancet Reg Health Eur, 10, pp.100208~ (2021)
  42. "Cruickshank S. COVID vaccine effects wane over time but still prevent death and severe illness"[URL]
  43. Gilkey MB, "Vaccination confidence and parental refusal", delay of early childhood vaccines, 2016, pp.11, e0159087~
  44. "COVID-19: Vaccines work"[URL]
  45. "Deaths and hospitalizations averted by rapid US vaccination rollout"[URL]
  46. "COVID-19 vaccine surveillance report published"[URL]
  47. Rossman H, "COVID-19 dynamics after a national immunization program in Israel", Nat Med, 27, pp.1055~1061 (2021)
  48. "How vaccines are affecting Covid-19 outbreaks globally"[URL]
  49. "What is herd immunity2020"[URL]
  50. "The importance of global COVID-19 vaccination" (2021)[URL]
  51. "The Vaccine Alliance. Why is a global Covid-19 vaccine rollout vital?"[URL]
  52. MacDonald NE, "Risk perception, risk management and safety assessment : what can governments do to increase public confidence in their vaccine system", Biologicals, 40, pp.384~388 (2012)
  53. Brosh-Nissimov T, "BNT162b2vaccine breakthrough : clinical characteristics of 152 fully vaccinated hospitalized COVID-19 patients in Israel", Clin Microbiol Infect, 27, pp.1652~1657 (2021)
  54. "Severe breakthrough infections remain very rare, despite rising concerns"[URL]
  55. "Study: Severe COVID-19 breakthrough cases found in older people with underlying conditions"[URL]
  56. Havers FP, "COVID-19-associated hospitalizations among vaccinated and unvaccinated adults ≥18 years - COVID-NET, 13 states, January 1 - July 24, 2021", medRxiv, pp.21262356~ (2021)
  57. .,
  58. "Pfizer and Moderna say Covid vaccine protection wanes over time"[URL]
  59. "What to know about breakthrough infections and the Delta variant"[URL]
  60. "Some vaccinated people have gotten Covid-19. That’s no reason to panic"[URL]
  61. "9 vaccinated Yankees players and staff tested positive for Covid—Here’s how that happens"[URL]
  62. "Confidence in COVID-19 vaccine faces challenge of Delta variant"[URL]
  63. "COVID-19 vaccine breakthrough cases: Data from the States"[URL]
  64. "Breakthrough COVID-19: What’s the real risk?"[URL]
  65. "Should you be worried about Covid if you’re vaccinated? Experts explain breakthrough cases"[URL]
  66. "Characterizing COVID-19 Breakthrough Infections"[URL]
  67. "How long will your coronavirus vaccination last?"[URL]
  68. Butt AA, "Outcomes among patients with breakthrough SARSCoV-2 infection after vaccination", Int J Infect Dis, 110, pp.353~358 (2021)
  69. Kuter B, "Ten year follow-up of healthy children who received one or two injections of varicella vaccine", Pediatr Infect Dis J, 23, pp.132~137 (2004)
  70. "Study finds long COVID is less likely after breakthrough infections"[URL]

관련 논문AI추천

Coronavirus disease 2019 (COVID-19) vaccine platforms: how novel platforms can prepare us for future pandemics: a narrative reviewJae Kyung Lee, Ok Sarah Shin영남대학교 의과대학 · Journal of Yeungnam Medical Science2022 · 제39권 제2호A Promising Vaccination Strategy against COVID-19 on the Horizon: Heterologous Immunization명진종, Mattoo Sameer-ul-Salam한국미생물·생명공학회 · Journal of Microbiology and Biotechnology2021 · 제31권 제12호COVID-19 Therapeutics: An Update on Effective Treatments Against Infection With SARS-CoV-2 Variants김정기, 송영천, 이종길, Españo Erica, Kim Sang-Hyun, Padasas Bill Thaddeus대한면역학회 · Immune Network2023 · 제23권 제2호SARS-CoV-2 Breakthrough Infection after mRNA-1273 Booster among CoronaVac-Vaccinated Healthcare WorkersDe Samakto Baringin, Jo Juandy, Kamarga Lina, Santi Theresia대한감염학회 · Infection and Chemotherapy2022 · 제54권 제4호SARS-CoV-2 Omicron Variant of Concern: Everything You Wanted to Know about Omicron but Were Afraid to Ask최준용, Davey M. Smith, Dong Hoon Shin연세대학교의과대학 · Yonsei Medical Journal2022 · 제63권 제11호Progress and Challenges in the Development of COVID-19 Vaccines and Current Understanding of SARS-CoV-2- Specific Immune Responses구근본, 김균도, 김성준, 김천생, 이수민, 황인수한국미생물·생명공학회 · Journal of Microbiology and Biotechnology2020 · 제30권 제8호

이 간행물의 다른 논문 (17건)

HIV-Related Stigma Reduction in the Era of Undetectable Equals Untransmittable: The South Korean Perspective서보경, 최재필pp. 661-675Long-Acting Injectable Antiretroviral Agents for HIV Treatment and Prevention김연숙pp. 686-695Reduced Susceptibility to Biocides among Enterococci from Clinical and Non-Clinical SourcesSaffari Fereshteh, Sobhanipoor Mohammad Hossein, Ahmadrajabi Roya, Nave Hossein Hosseinipp. 696-704The Use of Personal Protective Equipment among Frontline Nurses in a Nationally Designated COVID-19 Hospital during the Pandemic조인희, 민혜숙, 문세람, 성호경, 전재현, 장윤미pp. 705-717Clinical Characteristics and Risk Factors for Severe Disease of Coronavirus Disease 2019 in a Low Case Fatality Rate Region in Korea허상택, 오현주, 유정래, 김미선, 이향란pp. 718-729
원문 보기