팔길이와 인지저장능
Arm length for cognitive reserve capacity
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참고문헌
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초록
성인의 신체계측인자는 생후 초기 생활환경의 표지자라 알려져 있고, 또한 노년기 인지장애 및 치매와 연관될 수 있다고 알려져 있다. 본 연구에서는 팔길이와 인지기능간의 관련성에 대하여 살펴보고자 한다. 본 연구는 2003년도 남원지역 노암동 일대에 거주하는 235명의 65세 이상 노령층을 대상으로 시행되었다. 인지기능 및 일상생활 기능평가는 한국판 간이정신상태검사 개정판 (K-mMMSE) 및 한국판 도구적 일상생활기능 (K-IADL)로 시행되었다. 모든 참가자에 대해 임상검진을 실시하였고, 치매 여부를 최종적으로 결정하였다. 신체검진은 총팔길이를 포함하였다. 팔길이는 인지 및 일상생활기능 검사와 유의한 상관관계를 보였고, 연령, 성별, 교육 등의 중요한 변인을 보정한 다변량 선형회귀분석에서도 이들 연관성은 독립적이었다. 팔길이의 감소와 치매는 유의한 연관성을 보였고(오즈비(odds ratio)=1.23, 95% 신뢰구간=1.13-1.35, <0.001), 또한 다변량로지스틱회귀분석을 통해 중요한 변수를 모두 보정한 뒤에도 독립적인 연관성이 유의하게 지속되었다. 팔길이는 노인에서의 인지기능 및 치매와 독립적인 연관성을 갖고, 이러한 연관성은 교육 여부와도 무관하여 인지저장 능의 지표로 유용하게 사용될 수 있다고 생각된다.
Abstract
Some kind of adult anthropometry was reported as a marker of early life environment, and could be associated with cognitive impairment or dementia. This study aimed to examine whether arm length was associated with cognitive and functional abilities. Screening interviews were conducted in community dwelling 235 individuals aged 65 and over. The assessment scales included the Korean version of modified Mini-Mental State Examination (KmMMSE) for cognition, and the Korean Instrumental Activities of Daily Living (K-IADL) for functional ability. All the participants were examined clinically and a diagnosis of dementia was ascertained. Anthropometric measurements included total arm span. Arm length correlated significantly with the cognitive and functional scales. In the multivariate regression models, these associations were significant, independent of age, sex, education, and other variables. Shorter arm length was also significantly associated with dementia(odds ratio=1.23, 95% confidence intervals=1.13-1.35; p<0.001), and the significance persisted even after an adjustment for the potential confounders. Arm length could indicate cognitive and functional ability. Anthropometric measurements like arm length could provide a stable indicator for cognitive and functional reserve capacity, independently of educational attainment.
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