노인에서 비만과 MMSE-K 점수의 연관성에 관한 연구
Association between Obesity Indices and MMSE-K in Elderly
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참고문헌
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초록
Objectives The aim of this study was to investigate associations between obesity indices and cognitive functions using data from individuals older than 65 years in South Korea. Methods A total of 151 Koreans older than 65 years participated in this study voluntarily. Obesity was determined using body mass index (BMI) and waist-hip ratio (WHR). Cognitive function was evaluated using the Korean version of the Mini-Mental State Examination (MMSE-K). The participants were divided into four groups according to BMI : underweight (BMI<18.5), normal (18.5≤BMI<23.0), overweight (23.0≤BMI<25.0), and obesity (BMI≥25.0), and two groups according to WHR : normal (WHR<18.5) and abdominal obesity (WHR≥0.8). Baseline characteristics were compared among different BMI or WHR subgroups. Results Older age and smoking habits showed an association with poor cognitive function. Among different BMI groups, the overweight group had the highest scores of MMSE-K ; the item scores for time and place orientation (4.48±0.770 and 4.80±0.500) and attention/calculation (4.00±1.258) as well as total score (25.88±2.877). Overweight in BMI showed an association with better cognitive function (ORadjusted=0.098, 95% confidence interval=0.017-0.577). Conclusion In this study, the overweight group measured by BMI showed better cognitive function than other groups. Overweight in elderly might be acceptable in order to maintain cognitive performance. Further investigation regarding the underlying mechanism explaining the relationship between cognitive function and body weight will be needed.
Abstract
Objectives The aim of this study was to investigate associations between obesity indices and cognitive functions using data from individuals older than 65 years in South Korea. Methods A total of 151 Koreans older than 65 years participated in this study voluntarily. Obesity was determined using body mass index (BMI) and waist-hip ratio (WHR). Cognitive function was evaluated using the Korean version of the Mini-Mental State Examination (MMSE-K). The participants were divided into four groups according to BMI : underweight (BMI<18.5), normal (18.5≤BMI<23.0), overweight (23.0≤BMI<25.0), and obesity (BMI≥25.0), and two groups according to WHR : normal (WHR<18.5) and abdominal obesity (WHR≥0.8). Baseline characteristics were compared among different BMI or WHR subgroups. Results Older age and smoking habits showed an association with poor cognitive function. Among different BMI groups, the overweight group had the highest scores of MMSE-K ; the item scores for time and place orientation (4.48±0.770 and 4.80±0.500) and attention/calculation (4.00±1.258) as well as total score (25.88±2.877). Overweight in BMI showed an association with better cognitive function (ORadjusted=0.098, 95% confidence interval=0.017-0.577). Conclusion In this study, the overweight group measured by BMI showed better cognitive function than other groups. Overweight in elderly might be acceptable in order to maintain cognitive performance. Further investigation regarding the underlying mechanism explaining the relationship between cognitive function and body weight will be needed.
참고문헌 (30)
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