한국 66세 여성의 골다공증 유병상태 및 관련 요인
Prevalence of Osteoporosis, Related Factors in 66-Year-Old Women in Korea
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연구배경: 노인 인구가 빠르게 증가하고 있어 골다공증과 골절 증가로 사회경제적 비용이 증가하고 있다. 저자등은 66세 여성 노인을 대상으로 골다공증과 노인신체기능과의 연관성을 알아보고자 본 연구를 진행하였다. 방법: 2007년 5월부터 12월까지 경희의료원에서 생애전환기 검진을 받은 만 66세 여성 중 골밀도 검사를 시행 받은 전체 193명을 대상으로 단면연구를 시행하였다. 병력,운동, 흡연력 및 음주력은 자기기입식 설문조사를 통해 파악하였고, 체중, 신장, 허리둘레를 측정하였다. 요추 골밀도는 이중에너지 방사선 흡수계측기(dual energy X-ray absorptiometry)로 측정하였으며, ‘Timed up and go (TUG) test’와 평형 계측으로 ‘One-leg balance (OLB) test’의 시간을 측정하였다. 골다공증과 관련된 인자와 위험도는 상관 분석과 다중 로지스틱 회귀분석으로 분석하였다. 결과: 골다공증의 유병률은 25.9%였다. 골다공증군에서체중과 체질량지수가 유의하게 낮게 나타났다. TUG test 결과 골다공증군에서 소요 시간이 증가되었으며, OLB test 결과 유의한 차이가 없었다. 로지스틱 회귀분석 결과골다공증 위험요인은 작은 키, 낮은 체질량지수, 10초 초과TUG (odds ratio, 4.052; P=0.049)로 나타났다. 평형성은 요추 골밀도와 연관성이 없었다. 결론: 한국 66세 여성의 요추 골다공증은 4명에 1명 꼴로 많았으며 노인 운동기능 평가지표인 TUG 시간과 작은키, 낮은 체질량 지수가 관련요인으로 나타났다. 향후 간단한 운동기능검사인 TUG 시간과 골절 발생과의 연관성에관한 연구가 필요할 것이다.
Abstract
Background: With the rapid increase in the elderly population and the ensuing increase in osteoporosis and subsequent fractures, there has been a rise in socioeconomic costs. This study evaluated the relationship between osteoporosis and physical function in 66-year-old Korean women. Methods: All of the 193 Korean women aged 66 years were recruited from life-transition health examinations from May to December, 2007. Background information was collected through a self-administered questionnaire;and height, weight, and waist circumference were measured. Bone mineral density of the lumbar spine was measured with the Dual Energy X-ray Absorptiometry and the ‘timed up and go (TUG)’ and ‘one-leg balance (OLB)’ tests were administered. Risk factors for osteoporosis were analyzed by correlation coefficients and binary logistic regression analysis. Results: The prevalence of osteoporosis for 66-year-old women was 25.9%. A short stature and lower body mass index (BMI) were associated with osteoporosis of the lumbar spine. A longer time to complete the TUG test (>10 second) was associated with a 4-time higher prevalence of lumbar osteoporosis, which was not observed with the OLB test. Conclusions: One out of four 66-year-old Korean women had osteoporosis. A longer TUG time, short stature,and lower BMI were associated with osteoporosis.
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