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복합간세포-담관암종: 병리와 분류

Combined Hepatocellular-Cholangiocarcinoma: Recent Progress in Pathology and Classification

최준혁
영남대학교 의과대학 (Yeungnam University College of Medicine)|2011.06|Journal of Yeungnam Medical Science|제28권 제1호|pp. 1-12

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참고문헌

키워드

ClassificationStem cellImmunohistochemistryLiverCombined hepatocellular-cholangiocarcinoma
주제분류의학일반

초록

Primary liver carcinomas have been classified into hepatocellular carcinoma, cholangiocarcinoma, and combined hepatocellular-cholangiocarcinoma (CHC). CHC is a tumor containing unequivocal, intimately mixed elements of both hepatocellular carcinoma and cholangiocarcinoma. It forms a small but significant proportion of primary liver carcinomas. The origin and pathogenesis of CHC have not been well established. According to the 2010 WHO classification, CHCs are categorized into 2 groups: the classical type and a subtype with stem cell features. This review describes recent progress in pathology and classification of CHC.

Abstract

Primary liver carcinomas have been classified into hepatocellular carcinoma, cholangiocarcinoma, and combined hepatocellular-cholangiocarcinoma (CHC). CHC is a tumor containing unequivocal, intimately mixed elements of both hepatocellular carcinoma and cholangiocarcinoma. It forms a small but significant proportion of primary liver carcinomas. The origin and pathogenesis of CHC have not been well established. According to the 2010 WHO classification, CHCs are categorized into 2 groups: the classical type and a subtype with stem cell features. This review describes recent progress in pathology and classification of CHC.

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