풍부한 림프버팀질을 동반한 간세포암종: 2예 보고
Hepatocellular carcinoma with lymphoid stroma: report of two cases
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초록
전형적인 간세포암종으로 특징적으로 풍부한 림프버팀질을 보이는 두 사례를 보고하였다. 이러한 형태적 특징을 가진 유형의 빈도와 예후와의 관련성에 대한 연구가 필요할 것으로 생각한다.
Abstract
We report two cases of hepatocellular carcinoma with prominent lymphocytic infiltration, which has been described as a subtype of hepatocellular carcinoma with good prognosis. One case showed lymphoid follicles and dense lymphocytic infiltrates within the tumor and its periphery, and the other case showed marked lymphocytic infiltration in the cancerous tissue. Piecemeal necrosis of cancer cells and atypical reactive changes were evident. The two cases were seronegative for hepatitis B surface antigen, antibody to hepatitis C virus, and Epstein-Barr virus DNA. One of the cases showed Clonorchis infestation. The prognostic significance of lymphocytic stroma in hepatocellular carcinoma requires further investigation.
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