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Fatal progressive right heart failure in a pancreatic cancer patient

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초록

Pulmonary tumor thrombotic microangiopathy (PTTM) is a rare but fatal complication of cancer and causes pulmonary hypertension and acute/subacute right heart failure. PTTM is most commonly associated with gastric cancer and more rarely associated with pancreatic cancer. We report a case of progressive right heart failure associated with clinically diagnosed pancreatic cancer, suggesting PTTM.

Abstract

Pulmonary tumor thrombotic microangiopathy (PTTM) is a rare but fatal complication of cancer and causes pulmonary hypertension and acute/subacute right heart failure. PTTM is most commonly associated with gastric cancer and more rarely associated with pancreatic cancer. We report a case of progressive right heart failure associated with clinically diagnosed pancreatic cancer, suggesting PTTM.

참고문헌 (8)

  1. von Herbay A, "Pulmonary tumor thrombotic microangiopathy with pulmonary hypertension", Cancer, 66, pp.587~592 (1990)
  2. Price LC, "Tumoral pulmonary hypertension", Eur Respir Rev, 28, pp.180065~ (2019)
  3. Price LC, "Pulmonary tumour thrombotic microangiopathy", Curr Opin Pulm Med, 22, pp.421~428 (2016)
  4. Chun YS, "8th edition of the AJCC cancer staging manual : pancreas and hepatobiliary cancers", Ann Surg Oncol, 25, pp.845~847 (2018)
  5. Fujishiro T, "A case report of pulmonary tumor thrombotic microangiopathy(PTTM)caused by esophageal squamous cell carcinoma", Esophagus, 10, pp.247~251 (2013)
  6. Patrignani A, "Pulmonary tumor thrombotic microangiopathy: the challenge of the antemortem diagnosis", J Cardiovasc Med(Hagerstown), 15, pp.828~833 (2014)
  7. Godbole RH, "Pulmonary tumor thrombotic microangiopathy : a systematic review", Pulm Circ, 9 (2019)
  8. Uruga H, "Pulmonary tumor thrombotic microangiopathy : a clinical analysis of 30 autopsy cases", Intern Med, 52, pp.1317~1323 (2013)

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