인공와우 환자에서의 대뇌피질청각유발전위의 측정: 예비 연구
Recordings of Cortical Auditory Evoked Potentials in Cochlear Implant Listeners: A Preliminary Study
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Background and Objectives There is a need for fast and reliable objective measures of cochlear implant (CI) performance, especially in young children. The aim of the study was to investigate the detection and characterization of cortical auditory evoked potentials (CAEP) of different types of sound stimulation in CI listeners using a commercially available system, HEARLab™. Subjects and Method Sound field CAEPs were obtained from 10 CI listeners, using three natural speech sounds (/m/, /g/, and /t/) presented at 55, 65, and 75 dB SPL. Detection rates, the latencies and amplitudes of CAEP waves were analyzed and compared with those of the normal hearing (NH) group. Results It was possible to detect CAEP responses in all CI listeners. Of the three stimuli (/m/, /g/, /t/), /g/ was the most robust waveform, although this was not statistically significant. Latencies for the /m/ stimulus were relatively longer than those for /t/ and especially for /g/, suggesting that CI listeners hear high-frequency sounds better than low-frequency sounds. When compared to the NH group, CAEP of CI listeners tended to show smaller amplitudes of various waves and longer latencies especially at P1 wave. Conclusion CAEP responses could be obtained in all CI listeners and normal adults successfully, indicating that CAEP can be applied clinically as an objective assessment tool of hearing. Further studies are needed for CI listeners especially in infants and toddlers using this protocol to assess its clinical usefulness. Korean J Otorhinolaryngol-Head Neck Surg 2016;59(6):430-6
Abstract
Background and Objectives There is a need for fast and reliable objective measures of cochlear implant (CI) performance, especially in young children. The aim of the study was to investigate the detection and characterization of cortical auditory evoked potentials (CAEP) of different types of sound stimulation in CI listeners using a commercially available system, HEARLab™. Subjects and Method Sound field CAEPs were obtained from 10 CI listeners, using three natural speech sounds (/m/, /g/, and /t/) presented at 55, 65, and 75 dB SPL. Detection rates, the latencies and amplitudes of CAEP waves were analyzed and compared with those of the normal hearing (NH) group. Results It was possible to detect CAEP responses in all CI listeners. Of the three stimuli (/m/, /g/, /t/), /g/ was the most robust waveform, although this was not statistically significant. Latencies for the /m/ stimulus were relatively longer than those for /t/ and especially for /g/, suggesting that CI listeners hear high-frequency sounds better than low-frequency sounds. When compared to the NH group, CAEP of CI listeners tended to show smaller amplitudes of various waves and longer latencies especially at P1 wave. Conclusion CAEP responses could be obtained in all CI listeners and normal adults successfully, indicating that CAEP can be applied clinically as an objective assessment tool of hearing. Further studies are needed for CI listeners especially in infants and toddlers using this protocol to assess its clinical usefulness. Korean J Otorhinolaryngol-Head Neck Surg 2016;59(6):430-6
참고문헌 (20)
- Sharma A, "A sensitive period for the development of the central auditory system in children with cochlear implants: implications for age of implantation", Ear Hear, 23(6), pp.532~539 (2002)
- Munro KJ, "Obligatory cortical auditory evoked potential waveform detection and differentiation using a commercially available clinical system:HEARLabTM", Ear Hear, 32(6), pp.782~786 (2011)
- Gordon KA, "Characterizing responses from auditory cortex in young people with several years of cochlear implant experience", Clin Neurophysiol, 119(10), pp.2347~2362 (2008)
- Ponton CW, "Of kittens and kids: altered cortical maturation following profound deafness and cochlear implant use", Audiol Neurootol, 6(6), pp.363~380 (2001)
- Harris RJ, "A primer of multivariate statistics" (2001), Lawrence Erlbaum Associates, Inc
- Liégeois-Chauvel C, "Evoked potentials recorded from the auditory cortex in man:evaluation and topography of the middle latency components", Electroencephalogr Clin Neurophysiol, 92(3), pp.204~214 (1994)
- Jiwani S, "Central auditory development after long-term cochlear implant use", Clin Neurophysiol, 124(9), pp.1868~1880 (2013)
- Golding M, "The detection of adult cortical auditory evoked potentials (CAEPs) using an automated statistic and visual detection", Int J Audiol, 48(12), pp.833~842 (2009)
- Firszt JB, "Neurophysiology of cochlear implant users I: effects of stimulus current level and electrode site on the electrical ABR, MLR, and N1-P2 response", Ear Hear, 23(6), pp.502~515 (2002)
- Dorman MF, "Central auditory development: evidence from CAEP measurements in children fit with cochlear implants", J Commun Disord, 40(4), pp.284~294 (2007)
- Hossain MD, "A clinical study of cortical auditory evoked potentials in cochlear implantees", Indian J Otolaryngol Head Neck Surg, 65(Suppl 3), pp.587~593 (2013)
- Gilley PM, "Developmental changes in refractoriness of the cortical auditory evoked potential", Clin Neurophysiol, 116(3), pp.648~657 (2005)
- Visram AS, "Cortical auditory evoked potentials as an objective measure of behavioral thresholds in cochlear implant users", Hear Res, 327, pp.35~42 (2015)
- Lightfoot G, "Cortical electric response audiometry hearing threshold estimation: accuracy, speed, and the effects of stimulus presentation features", Ear Hear, 27(5), pp.443~456 (2006)
- Van Dun B, "Sensitivity of cortical auditory evoked potential detection for hearing-impaired infants in response to short speech sounds", Audiol Res, 2(1), pp.e13~ (2012)
- Korczak PA, "Effects of sensorineural hearing loss and personal hearing AIDS on cortical event-related potential and behavioral measures of speech-sound processing", Ear Hear, 26(2), pp.165~185 (2005)
- Kraus N, "Speech sound representation, perception, and plasticity: a neurophysiologic perceptive", Audiol Neurootol, 3(2-3), pp.168~182 (1998)
- Pearce W, "Cortical auditory evoked potentials in the assessment of auditory neuropathy: two case studies", J Am Acad Audiol, 18(5), pp.380~390 (2007)
- Rance G, "Speech perception and cortical event related potentials in children with auditory neuropathy", Ear Hear, 23(3), pp.239~253 (2002)
- Golding M, "The relationship between obligatory cortical auditory evoked potentials (CAEPs) and functional measures in young infants", J Am Acad Audiol, 18(2), pp.117~125 (2007)