편도에서 진단된 Immunoglobulin G4 관련 질환: 증례보고 및 문헌 고찰
Immunoglobulin G4-Related Disease Affecting the Tonsil: Case Report and Literature Review
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초록
Immunoglobulin G4-related disease (IgG4-RD) can involve multiple sites throughout thebody. The most commonly affected sites in the head and neck are the salivary and lacrimalglands, respectively. Very few cases of IgG4-RD manifesting in the tonsils have been report-ed. Herein, we report the imaging findings of a 49-year-old female with pathologically con-firmed IgG4-RD after a right-side tonsillectomy. The lesion showed diffuse homogeneous en-hancement and appeared isointense and slightly hyperintense on T1- and T2-weightedmagnetic resonance imaging, respectively. Diffusion restriction was also observed, which wasconsidered to be due to the large number of IgG4-rich plasmacytes, and could vary dependingon the degree of fibrosis. As distinguishing IgG4-RD from other diseases based solely on im-aging is challenging, it is important to consider differential diagnosis, and clinical consider-ations are essential.
Abstract
Immunoglobulin G4-related disease (IgG4-RD) can involve multiple sites throughout thebody. The most commonly affected sites in the head and neck are the salivary and lacrimalglands, respectively. Very few cases of IgG4-RD manifesting in the tonsils have been report-ed. Herein, we report the imaging findings of a 49-year-old female with pathologically con-firmed IgG4-RD after a right-side tonsillectomy. The lesion showed diffuse homogeneous en-hancement and appeared isointense and slightly hyperintense on T1- and T2-weightedmagnetic resonance imaging, respectively. Diffusion restriction was also observed, which wasconsidered to be due to the large number of IgG4-rich plasmacytes, and could vary dependingon the degree of fibrosis. As distinguishing IgG4-RD from other diseases based solely on im-aging is challenging, it is important to consider differential diagnosis, and clinical consider-ations are essential.
참고문헌 (14)
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