Phenolic Acid Contents and ROS Scavenging Activity of Dandelion(Taraxacum officinale)
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The purpose of this study was to investigate the antioxidant activity of 80% ethanol extracts and various solvent fractions of dandelion (Taraxacum officinale) leaves and roots. Total phenolics and phenolic acid contents were also examined. The total phenol content of leaves and roots were 7.9±0.4% and 9.4±0.3%, respectively. Eight phenolic acids were separated by GC, among which caffeic acid (113.7 mg%)and m-courmaric acid (152.6 mg) were the dominant phenolic acids in leaves and roots, respectively. Amongst solvent fractions of leaves and roots, the ethyl acetate fraction showed the strongest radical scavenging activity. A strong correlation was found between total phenol content and electron-donating ability, and ABTS radical scavenging activity showed a similar trend as electron-donating ability. Hydroxyl-radical-scavenging activity and lipid peroxidation were significantly higher in the ethyl acetate fraction than other factions. In particular, the SOD-like activity was highest (43.6%) in the ethyl acetate fraction of dandelion leaves, and was higher than that of trolox. Thus, the ethyl acetate fraction of dandelion leaves exhibited significant phenol content, antioxidant activity, and free-radical-scavenging effects.
Abstract
The purpose of this study was to investigate the antioxidant activity of 80% ethanol extracts and various solvent fractions of dandelion (Taraxacum officinale) leaves and roots. Total phenolics and phenolic acid contents were also examined. The total phenol content of leaves and roots were 7.9±0.4% and 9.4±0.3%, respectively. Eight phenolic acids were separated by GC, among which caffeic acid (113.7 mg%)and m-courmaric acid (152.6 mg) were the dominant phenolic acids in leaves and roots, respectively. Amongst solvent fractions of leaves and roots, the ethyl acetate fraction showed the strongest radical scavenging activity. A strong correlation was found between total phenol content and electron-donating ability, and ABTS radical scavenging activity showed a similar trend as electron-donating ability. Hydroxyl-radical-scavenging activity and lipid peroxidation were significantly higher in the ethyl acetate fraction than other factions. In particular, the SOD-like activity was highest (43.6%) in the ethyl acetate fraction of dandelion leaves, and was higher than that of trolox. Thus, the ethyl acetate fraction of dandelion leaves exhibited significant phenol content, antioxidant activity, and free-radical-scavenging effects.
참고문헌 (36)
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