A Surge in the Seroprevalence of Toxoplasmosis among the Residents of Islands in Gangwha-gun, Incheon, Korea
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Seroepidemiological changes of Toxoplasma gondii infection among the residents of the islands of Gangwha-gun, Incheon for 2 years were surveyed and evaluated by ELISA using a crude extract antigen. In 2010, sera of 919 adult residents in Gyodong-myeon and 313 adults in Samsan-myeon were collected and checked for IgG antibody titers, which showed 14.5% (133 sera) and 19.8% (62 sera) positive rates, respectively. In 2011, sera of 955 adults in Gyodong-myeon and 341 adults in Samsan-myeon were examined, which showed an increase of positive rates to 23.8% (227 sera) and 31.7% (108 sera), respectively. Totally, the seroprevalence of the first year was 15.8% and it increased rapidly to 25.8% in the second year. The positive rates of both sexes increased simultaneously with the significant ratio of males to females by 1.7-2.2 fold (P<0.05). In both myeons, 661 sera were collected every year and showed changes in optical density (OD) in 177 sera; newly found as positives in 73 persons (11.0%), negative conversion in 10 persons (1.5%), and maintained or increased in 94 persons (14.2%). This rapid increase in the prevalence of toxoplasmosis in Gangwha islands may be due to in part peculiar changes in the toxoplasmic environment of the islands and presumably the consumption of the pork bred domestically within the islands or imported from high endemic nations. It is necessary to find out symptomatic toxoplasmic patients and confirm the risk factors for further infection in the islands of Gangwha-gun.
Abstract
Seroepidemiological changes of Toxoplasma gondii infection among the residents of the islands of Gangwha-gun, Incheon for 2 years were surveyed and evaluated by ELISA using a crude extract antigen. In 2010, sera of 919 adult residents in Gyodong-myeon and 313 adults in Samsan-myeon were collected and checked for IgG antibody titers, which showed 14.5% (133 sera) and 19.8% (62 sera) positive rates, respectively. In 2011, sera of 955 adults in Gyodong-myeon and 341 adults in Samsan-myeon were examined, which showed an increase of positive rates to 23.8% (227 sera) and 31.7% (108 sera), respectively. Totally, the seroprevalence of the first year was 15.8% and it increased rapidly to 25.8% in the second year. The positive rates of both sexes increased simultaneously with the significant ratio of males to females by 1.7-2.2 fold (P<0.05). In both myeons, 661 sera were collected every year and showed changes in optical density (OD) in 177 sera; newly found as positives in 73 persons (11.0%), negative conversion in 10 persons (1.5%), and maintained or increased in 94 persons (14.2%). This rapid increase in the prevalence of toxoplasmosis in Gangwha islands may be due to in part peculiar changes in the toxoplasmic environment of the islands and presumably the consumption of the pork bred domestically within the islands or imported from high endemic nations. It is necessary to find out symptomatic toxoplasmic patients and confirm the risk factors for further infection in the islands of Gangwha-gun.
참고문헌 (22)
- Tenter AM, "Toxoplasma gondii: from animals to humans", Int J Parasitol, 30, pp.1217~1258 (2000)
- Black MW, "Lytic cycle of Toxoplasma gondii", Microbiol Mol Biol Rev, 64, pp.607~623 (2000)
- Furtado JM, "Toxoplasmosis: A Global Threat", J Glob Infect Dis, 3, pp.281~284 (2011)
- 송경주, "Seroprevalence of toxoplasmosis in Korean pregnant women", The Korean Journal of Parasitology, 43(2), pp.1~10 (2005), 대한기생충학회
- Montoya JG, "Management of Toxoplasma gondii infection during pregnancy", Clin Infect Dis, 47, pp.554~566 (2008)
- Weiss LM, "Toxoplasmosis: A history of clinical observations", Int J Parasitol, 39, pp.895~901 (2009)
- Choi WY, "Foodborne outbreaks of human toxoplasmosis", J Infect Dis, 175, pp.1280~1282 (1997)
- 박영훈, "Clinical Features of Ocular Toxoplasmosis in Korean Patients", The Korean Journal of Parasitology, 49(2), pp.167~171 (2011), 대한기생충학회
- Kim MH, "A toxoplasmic uveitis case of a 60-year-old male in Korea", Korean J Parasitol, 38, pp.29~31 (2000)
- Choi WY, "Toxoplasma antibody titers by indirect latex agglutination test in patients of Kangnam St. Mary’s hospital and Cheju medical center", Korean J Parasitol, 27, pp.171~175 (1989)
- Choi WY, "Detection of antibodies in serum and cerebrospinal fluid to Toxoplasma gondii by indirect latex agglutination test and enzyme-linked immunosorbent assay", Korean J Parasitol, 30, pp.83~90 (1992)
- Yang HJ, "Seroprevalence of toxoplasmosis in the residents of Cheju island, Korea", Korean J Parasitol, 38, pp.91~93 (2000)
- 홍성종, "Maintained Seroprevalence of Toxoplasmosis among the Residents of Jeju Island, Korea", The Korean Journal of Parasitology, 49(3), pp.309~311 (2011), 대한기생충학회
- Hye-Jin Ahn, "Seroprevalence of Toxoplasmosis in the Residents of Cheorwon-gun, Gangwon-do, Korea", The Korean Journal of Parasitology, 50(3), pp.225~227 (2012), 대한기생충학회
- Sohn WM, "Western blot analysis of stray cat sera aga-inst Toxoplasma gondii and the diagnostic availability of monoclonal antibodies in sandwich-ELISA", Korean J Parasitol, 37, pp.249~256 (1999)
- Bahia-Oliviera LM, "Highly endemic, waterborne toxoplasmosis in north Rio de Janeiro state, Brazil", Emerg Infect Dis, 9, pp.55~62 (2003)
- Lee SE, "Prevalence of Toxoplasma gondii infection in feral cats in Seoul, Korea", J Parasitol, 97, pp.153~155 (2011)
- 이상은, "Prevalence of Toxoplasma gondii Infection in Stray and Household Cats in Regions of Seoul, Korea", The Korean Journal of Parasitology, 48(3), pp.267~270 (2010), 대한기생충학회
- 김혜연, "Prevalence of Toxoplasma gondii in Stray Cats of Gyeonggi-do, Korea", The Korean Journal of Parasitology, 46(3), pp.199~201 (2008), 대한기생충학회
- Katwere M, "Clinical presentation and aetiologies of acute or complicated headache among HIV-seropositive patients in a Ugandan clinic", J Int AIDS Soc, 12, pp.21~ (2009)
- Leligdowicz A, "Challenges in diagnosis, treatment and follow-up of patients presenting with central nervous system infections in a resource- limited setting", Mcgill J Med, 9, pp.39~48 (2006)
- Luft BJ, "Central nervous system Toxoplasmosis in HIV pathogenesis, Diagnosis, and Therapy", Curr Infect Dis Rep, 2, pp.358~362 (2000)