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해양 미생물 유래 해조 다당류 분해 효소의 특성 및 산업적 응용

Properties and Industrial Applications of Seaweed Polysaccharides-degrading Enzymes from the Marine Microorganisms.

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참고문헌

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주제분류생물학

초록

최근에 해조류 유래 기능성 소재는 항종양성, 항바이러스성, 항혈액응고 및 면역력 증강 등의 다양한 생리활성기능을 갖는 것으로 알려져 있다. 특히 해조 다당류를 저분자화하면 다양한 생체조절 기능성이 월등히 높게 나타나고 있음이 보고되고 있다. 따라서 해조 다당류를 해조류로부터 효과적으로 추출하는 방법의 최적화 및 해조 다당류의 저분자화를 통하여 해조 다당류 기능성 증진 방법에 대한 연구가활발히 진행되고 있다. 본 총설에서는 최근 부각되고 있는해양 미생물 유래 해조 다당류 분해효소를 이용한 기능성 신소재 개발 및 산업적 응용에 대하여 논하고자 한다.

Abstract

Recently seaweed polysaccharides have been extensively studied due to their various biological functions including antitumor, antiviral, anticoagulant, and anti-inflammatory activities. Although seaweed polysaccharides are known to possess numerous beneficial properties, their industrial applications have been limited due to the low inclusion efficiency and high cost of manufacturing involved in chemical hydrolysis. In addition, the smell of seaweed has been a limiting factor in its application in the food and cosmetic industries. Therefore, novel hydrolysis methods and the deodorization of seaweed are required if the extensive application of seaweed polysaccharides is to be seen. A number of studies have examined various seaweed polysaccharide-degrading enzymes, which have been isolated from marine microorganisms, and enzymatic hydrolysis processes have been investigated for the improvement of production yields and the bioefficacy of seaweed polysaccharides. This review is a synopsis on the properties of seaweed polysaccharidesdegrading enzymes from marine microorganisms and their industrial applications. The review reveals the pressing need for more concentrated research on the development of new biological materials from seaweed

참고문헌 (63)

  1. Araki, T., "Purification and characterization of agarases from amarine bacterium, Vibrio sp. PO-303", J. Mar. Biotechnol, 6, pp.260~265 (1998)
  2. Asia, Y., "Fucoidan induces apoptosis ofhuman HS-sultan cells accompanied by activation ofcaspase-3 and down-regulation of ERK pathway", Am. J.Hematol, 78, pp.7~14 (2005)
  3. Beer, L, "Engineering algae for biohydrogen and biofuel production", Current Opinion in Biotechnology, 20, pp.264~271 (2009)
  4. Beil, S., "Purification andcharacterization of the agaropectin sulfatase synthesized byPsedomonas aeruginosa PAO during growth in sulfate-freemedium and cloning of the arylsulfatase gene(atsA)", Eur. J.Biochem, 229, pp.385~394 (1995)
  5. Berteau, O, "Sulfated fucans, freshperspectives: structures, functions, and biological propertiesof sulfated fucans and an overview of enzymes activetoward this class of polysaccharide", Glycobiol, 13, pp.29~40 (2003)
  6. Buck, B. C, "The offshore ring: Anew system design for the open ocean aquaculture ofmacroalgae", J. Appl. Phycol, 16, pp.355~369 (2004)
  7. Chevolot, "Futherata on the structure of brown seaweed fucans: relationships with anticoagulant activity", Carbohydr. Res, 319, pp.154~165 (1999)
  8. Chisti,Y, "Biodiesel from microalgae", Biotechnol. Adv, 25, pp.294~306 (2007)
  9. 조은수, "효모 표층 Arylsulfatase에 의해 제조된 Agarose의 특성", 한국미생물·생명공학회지, 38(4), pp.428~433 (2010), 한국미생물·생명공학회
  10. Cho, K. J., "Antitumor effectand immunology activity of seaweeds toward sarcoma-180", Bull. Kor. Fish. Soc, 23, pp.345~352 (1990)
  11. Davidson, I. W., "Purification and properties of an alginate lyase from amarine bacterium", Biochem. J, 159, pp.707~713 (1976)
  12. De Hostos, E. L., "Purification and biosynthesis of a derepressible periplasmicarylsulfatase from Chlamydomonas reinharditii", J. Cell Biol, 106, pp.29~37 (1988)
  13. Do,J.H, "Extraction and purification of agar fromGelidium amansii", J. Korean Fish Soc, 30, pp.423~427 (1997)
  14. Dobashi, K., "Isolation and preliminary characterization of fucose containingsulfated polysaccharide with blood anticoagulantactivity from the brown seaweed", Carbohydr. Res, 194, pp.315~320 (1989)
  15. Dolan, T. C. S, "The carrageenans. II.The positions of the glycosidic linkages and sulphate estersin λ-carrageenan", J. Chem. Soc, pp.3534~ (1965)
  16. Duckworth, M, "Structure of ahar. I.Fractionation of a complex mixture of polysaccharides", Carbo. Res, 16, pp.189~197 (1971)
  17. Fisher, F. G, "The polyuronic acids ofbrown algae. Part I", Z. Physiol. Chem, 302, pp.186~203 (1955)
  18. Fu Xiao Ting, "Gene Cloning, Expression, and Characterization of a β-Agarase, AgaB34, from Agarivorans albus YKW-34", Journal of Microbiology and Biotechnology, 19(3), pp.257~264 (2009), 한국미생물·생명공학회
  19. Gacesa,P, "Alginates", Carbohydr. Polym, 8, pp.161~182 (1988)
  20. Guven, K. C., "Anticoagulant,fibrinolytic and antiaggregant activity of carrageenans andalginic acid", Botan. Marin, 34, pp.429~435 (1991)
  21. Haug, A., "A study ofconstitution of alginic acid by partial acid hydrolysis", Acta.Chemica. Scand, 20, pp.183~190 (1966)
  22. Henderson, M. J, "Arylsulfatase insalmonella typhymurium: Detection and influence of carbonsource and tyramine on its synthesis", J. Bacteriol, 139, pp.80~87 (1979)
  23. Hicks, S. J, "Heterologous expression offull-length and truncated forms of the recombinantguluronate-specific alginate lyase of Klebsiella pneumoniae", Enzyme Microbiol. Technol, 19, pp.68~73 (1996)
  24. Hoshi, M, "Arylsulfatase of sea-urchinsperm. 2. Arylsulfatase as a lysin of sea-urchins", Dev. Biol, 74, pp.343~350 (1980)
  25. Iwamoto, Y., "Purification and characterizationof bifunctional alginate lyase from Alteromonassp. strain no. 272 and its action on saturated oligomericsubstrates", Biosci. Biotechnol. Biochem, 65, pp.133~142 (2001)
  26. Jansen, H. J., "A novel mucin-sulphatase activityfound in Bukholderia cepacia and Pseudomonas aeruginosa", J. Med. Microbiol, 48, pp.551~557 (1999)
  27. John, R. P., "Micro and macroalgal biomass: a renewablesource for bioethanol", Bioresour. Technol, 102, pp.186~193 (2011)
  28. Joo, D. S., "Purification and characterization of theintracellular alginase from Vibrio sp. AL-145", Kor. J. Appl.Microbiol. Biotechnol, 23, pp.432~438 (1995)
  29. Joo, D. S., "Preparation of oligosaccharides from alginicacid enzymatic hydrolysis", Kor. J. Food Sci. Technol, 28, pp.146~151 (1996)
  30. Joo, D. S., "Isolation ofalginate-degrading bacteria and production of alginatedegrading activities by bacteria", Kor. J. Appl. Microbiol.Biotechnol, 21, pp.207~213 (1993)
  31. Jung, J. Y., "Studies on theefficient extraction process of alginic acid in sea tangle", Food Eng. Prog, 3, pp.90~97 (1999)
  32. Kato, I, "Antioxidative and antitumorigenic propertiesof agarooligosaccharide", Bio Industry, 17, pp.13~19 (1998)
  33. Kim, B. J., "Production of agarase from marine bacterium Bacilluscereus ASK202", Kor. J. Biotechnol. Bioeng, 13, pp.524~529 (1998)
  34. Kim, D. E., "Cloning andcharacterization of alginate lyase from a marine bacteriumStreptomyces sp. ALG-5", Mar. Biotechnol, 11, pp.10~16 (2009)
  35. KIM, "Inulooligosaccharide Production from Inulin by Saccharomyces cerevisiaeStrain Displaying Cell-Surface Endoinulinase", Journal of Microbiology and Biotechnology, 16(3), pp.360~367 (2006), 한국미생물·생공학회
  36. Mi-Jin Kim, "Constitutive overexpression of Pseudoalteromonas carrageenovora arylsulfatase in E. coli fed-batch culture", The Korean Journal of Chemical Engineering, 28(4), pp.1101~1104 (2011), 한국화학공학회
  37. 김옥주, "알긴산 분해 Methylobacterium sp. HJM27 균주의 분리 및 특성", 한국미생물·생명공학회지, 38(2), pp.144~150 (2010), 한국미생물·생명공학회
  38. Kong, J. Y., "Cloning and expression of an agarase gene forma marine bacterium Pseudomonas sp. w7", Biotechnol. Lett, 19, pp.23~26 (1997)
  39. Lee, B. H., "Alginate fiber", Fiber Technol. Ind, 13, pp.21~24 (2009)
  40. 이재화, "알긴산 분해 해양미생물의 분리 및 alginase 특성 평가", 생명과학회지, 13(5), pp.718~722 (2003), 한국생명과학회
  41. 이재형, "Alginate Lyase 생산 균주 Pseudomonas sp. N7151-6의 분리 및 특성", 한국미생물·생명공학회지, 37(4), pp.350~354 (2009), 한국미생물·생명공학회
  42. Lee, S, "Converting Carbohydrates Extracted from Marine Algae into Ethanol Using Various Ethanolic Escherichia coli Strains", APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 164(6), pp.878~888 (2011), HUMANA PRESS INC
  43. Lee, Y. S., "Antitumor and immunomodulating effects of seaweedstoward sarcoma-180 cell", J. Kor. Soc. Food Nutr, 21, pp.544~550 (1992)
  44. Linker, A, "Isolation and characterizationof an alginase from mucoid strains of Pseudomonasaeroguinosa", J. Bacteriol, 159, pp.958~964 (1984)
  45. Luning, K, "Mass cultivation of seaweeds:current aspects and approaches", J. Appl. Phycol, 15, pp.115~119 (2003)
  46. Miech, C., "Arylsulfatase from Klebsiella pneumoniaecarries aformylglycine generated from a serine", J. Biol. Chem, 273, pp.4835~4837 (1998)
  47. Nakashima, H., "Purification and characterizationof an avian myeloblastosis and human immunodeficiencyvirus reverse transcriptase inhibitor sulfated polysaccharideextracted from sea algae", Agents Chemother, 31, pp.1524~1528 (1987)
  48. Oh, C. H., "Cloning, purification and biochemical characterization of beta agarase from the marine bacterium Pseudoalteromonas sp AG4", JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY, 37, pp.483~494 (2010), Society for Industrial Microbiology
  49. Ohta, Y., "Purification and characterization of a novelα-agarase from a Thalassomonas sp", Curr. Microbiol, 50, pp.212~216 (2005)
  50. 이신영, "다시마 유래 Fucoidan의 In-vitro 포도당 및 담즙산 흡수지연 효과", KSBB Journal, 22(4), pp.265~269 (2007), 한국생물공학회
  51. Park, Y. H., "Symbioticformation of alginate lyase in mixed culture of bacteriaisolated from soil", J. Ferment. Bioeng, 69, pp.192~194 (1994)
  52. Pereira, M. S., "Structureand anticoagulant activity of sulfated fucans", J. Biol.Chem, 274, pp.7656~7667 (1999)
  53. Preeprame, S., "A novel antivirally active fucan sulfatederived from an edible brown alga", Chem. Pharm. Bull, 49, pp.484~485 (2001)
  54. Rehm, B. H. A, "Bacterial alginates: biosynthesisand applications", Appl. Microbiol. Biotechnol, 48, pp.281~288 (1997)
  55. 석지환, "Pichia pastoris에서 Zobellia galactanivorans 유래 재조합 β-Agarase의 고효율 분비생산", 한국미생물·생명공학회지, 38(1), pp.40~45 (2010), 한국미생물·생명공학회
  56. Scot, M., "Estimation of meiobenthic nematode diversity by nonspecialists", Marine Pollu. Bulletin, 18, pp.646~649 (1987)
  57. Temuujin,, U., "Overexpression and biochemical characterizationof DagA from Streptomyces coelicolor A3(2): anendo-type β-agarase producing neoagarotetraose and neoagarohexaose", Appl. Microbiol. Biotechnol[DOI]
  58. 조순영, "알긴산 분해균 Bacillus licheniformis AL-577가 생산하는 균체외 효소의 정제 및 특성", 한국식품영양과학회지, 35(2), pp.231~237 (2006), 한국식품영양과학회
  59. Wang, X., "Two-stage hydrolysisof invasive algal feedstock for ethanol fermentation", J.Integr. Plant Biol, 53, pp.246~252 (2011)
  60. Yang, J. S, "Effect of ionizing radiationon the extraction yield and viscosity of alginate", Korean J.Food Sci. Technol, 9, pp.194~198 (1997)
  61. 연지현, "Repeated-Batch Operation of Surface-Aerated Fermentor for Bioethanol Production from the Hydrolysate of Seaweed Sargassum sagamianum", Journal of Microbiology and Biotechnology, 21(3), pp.323~331 (2011), 한국미생물·생명공학회
  62. Yun, E. J., "Production of 3,6-anhydro-l-galactose fromagarose by agarolytic enzymes of Saccharophagus degradans2-40", 46, pp.88~93 (2011)
  63. Zhang, W. W, "Cloning, characterization,and molecular application of a beta-agarase gene fromVibrio sp. strain V134", Appl. Environ. Microbiol, 73, pp.2825~2831 (2007)

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