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Complete Genome Sequence of an optrA-positive Linezolid-resistant Staphylococcus rostri Strain PJFA-333 Isolated from a Pig in Korea

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초록

Linezolid, the first oxazolidinone introduced into human clinical use, has become a last resort antibiotic in treatment of serious infections caused by Gram-positive pathogens, including methicillin-resistant staphylococci and vancomycin-resistant enterococci. Although oxazolidinones are strictly prohibited for use in food-producing animals, occurrence of linezolid-resistant staphylococci has recently been reported in livestock farms in Korea. Here, we report the complete genome sequence of an optrA-positive linezolid-resistant Staphylococcus rostri strain PJFA-333 isolated from a pig farm in Korea.

Abstract

Linezolid, the first oxazolidinone introduced into human clinical use, has become a last resort antibiotic in treatment of serious infections caused by Gram-positive pathogens, including methicillin-resistant staphylococci and vancomycin-resistant enterococci. Although oxazolidinones are strictly prohibited for use in food-producing animals, occurrence of linezolid-resistant staphylococci has recently been reported in livestock farms in Korea. Here, we report the complete genome sequence of an optrA-positive linezolid-resistant Staphylococcus rostri strain PJFA-333 isolated from a pig farm in Korea.

참고문헌 (7)

  1. Lee GY, "Co-occurrence of cfr-mediated linezolid-resistance in ST398 LA-MRSA and non-aureus staphylococci isolated from a pig farm", Vet. Microbiol, 266, pp.109336~ (2022)
  2. Schwarz S, "Identification of a plasmid-borne chloramphenicol-florfenicol resistance gene in Staphylococcus sciuri", Antimicrob. Agents Chemother, 44, pp.2530~2533 (2000)
  3. Wang Y, "A novel gene, optrA, that confers transferable resistance to oxazolidinones and phenicols and its presence in Enterococcus faecalis and Enterococcus faecium of human and animal origin", J. Antimicrob. Chemother, 70, pp.2182~2190 (2015)
  4. Overbeek R, "The SEED and the Rapid Annotation of microbial genomes using Subsystems Technology(RAST)", Nucleic Acids Res, 42, pp.D206~D214 (2014)
  5. Seemann T, "Prokka : rapid prokaryotic genome annotation", Bioinformatics, 30, pp.2068~2069 (2014)
  6. Yoon SH, "A large-scale evaluation of algorithms to calculate average nucleotide identity", Antonie Van Leeuwenhoek, 110, pp.1281~1286 (2017)
  7. Clinical and Laboratory Standards Institute, "Performance Standards for Antimicrobial Susceptibility Testing M100 32th edition", ~ (2022)

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