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논문KCI 등재

불안을 동반한 주요우울장애 환자에 대한 뇌파 알파 비대칭의 특성 연구

Electroencephalographic alpha asymmetry in major depressive disorder patients with anxiety symptom

이승민|이소희|양병환|이준석
대한생물정신의학회 (The Korean Society Of Biological Psychiatry)|2007.02|생물정신의학 (Journal of Korean Society of Biological Psychiatry)|제14권 제1호|pp. 42-47

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참고문헌

주제분류정신과학

초록

Abstract

Objectives : Studies have reported differences between depressed adults and controls in quantitative measures of EEG alpha asymmetry, but, there are few using Korean subjects. So, the present study compared EEG regional alpha asymmetries of patients having a major depressive disorder (MDD) and normal controls. Methods : The subjects in this study were 11 unmedicated unipolar depressed patients and 11 non-depressed, age matched controls. Resting EEG (eyes closed and eyes open) was recorded from each participant using 8 scalp electrodes. Beck Depression Inventory(BDI), 17-item Hamilton Depression Rating Scale(HDRS), Zungs Self-Rating Depression Scale(SDS) and Spielbergers State-Trait Anxiety Inventory(STAI) were used to evaluate depression and anxiety symptoms. Results : The severities of depression measured by self-report questionnaires were positively associated with those of anxiety (state and trait); The subjects were both anxious and depressed. Anxious-depressed patients differed from controls in alpha asymmetry at T4 channels. They showed evidence of greater activation over right than left temporal site. Conclusion : These findings are consistent with the previousely reported alpha asymmetry of depressed patients with an anxiety disorder. The failure to find the evidence of reduced right parietal activity in depression presumed to be due to opposing effects of comorbid anxiety on parietotemporal activity

참고문헌 (24)

  1. Berger H, "Uber das elektrenkephalogramm des menschen", 87, pp.527~550 (1929)
  2. Graae F, "Abnormality of EEG Alpha Asymmetry Adolescent Suicide Attempters in Female.", 40, pp.706~713 (1996)
  3. Davidson R, "Effects of lateralized presentations of faces on self-reports of emotion and EEG asymmetry in depressed and non-depressed subjects", 22, pp.353~364 (1985)
  4. Davidson R, "Frontal brain asymmetry predicts infants' response to maternal separation", 98, pp.127~131 (1989)
  5. Davidson R, "Anterior cerebral asymmetry and the nature of emotion", 20, pp.125~151 (1992), Brain Cogn
  6. Henriques JB, "Left frontal hypoactivation in depression", 100, pp.535~545 (1991)
  7. Henriques JB, "Regional brain electrical asymmetries discriminate between previously depressed subjects and healthy controls", 99, pp.22~31 (1990)
  8. Tucker DM, "Right frontal lobe activation and right hemisphere performance", 38, pp.169~174 (1981)
  9. Schaffer CE, "Frontal and parietal electroencephalogram asymmetry in depressed and nondepressed subjects", 18, pp.753~762 (1983)
  10. Davidson R, "Task-dependent EEG asymmetry discriminates between depressed and non-depressed subjects", 24, pp.585~ (1987)
  11. 한오수, "DSM-IV의 제1축 장애의 구조화된 임상적 면담 연구용 판"
  12. Rhee MK, "A standardization study of Beck Depression Inventory-Korean Version (K-BDI) I: reliability and factor analysis.", 4, pp.77~95 (1995)
  13. Hamilton M, "A rating scale for depression", 23, pp.56~62 (1960)
  14. 이영호, "MMPI-D척도의 신뢰도 및 타당도에 대한 연구", pp.98~113
  15. Kim JT, "A study based on the standardization of the STAI for Korea", 21, pp.69~75 (1978)
  16. American Electroencephalographic Society, "Guideline thirteen:guidelines for standard electrode position nomenclature", 11, pp.111~113 (1994)
  17. Bruder GE, "Regional Brain Asymmetries in Major Depression with or without an Anxiety Disorder: A Quantitative Electroencephalographic Study.", 41, pp.939~948 (1997)
  18. Heller W, "Patterns of perceptual asymmetry in depression and anxiety: Implications for neuropsychological models of emotion and psychopathology.", 104, pp.327~333 (1995)
  19. Miller EN, "Hemispheric asymmetries of function in patients with major affective disorders.", 29, pp.173~183 (1995)
  20. Wexler BE, "perception of emotion and treatment response in obsessive-compulsive disorder", pp.900~908
  21. Heller W, "Regional brain activity in emotion:A framework for understanding cognition in depression.", 11, pp.637~661 (1997)
  22. Maser J, "Comorbidity in Anxiety and Mood Disorders" (1990), American Psychiatric Press
  23. Sloman L, "The interactive functioning of anxiety and depression in agonistic encounters and reconciliation.", 90, pp.93~99 (2006)
  24. Davidson R, "Anterior electrophysiological asymmetries, emotion and depression: Conceptual and methodological conundrums.", 35, pp.607~614 (1998)

관련 논문AI추천

주요우울증에서 우울과 불안 증상의 심각도에 따른 뇌파 A1, A2, Percent 비대칭 지표들의 특성 연구김기성, 양병환, 오동열, 이준석대한신경정신의학회 · 신경정신의학2007 · 제46권 제2호우울증 환자와 정상인의 전두엽 알파파 비대칭 현상 연구안창일, 최승원, 제갈은주한국임상심리학회 · Korean Journal of Clinical Psychology2008 · 제27권 제4호주요우울증환자의 정량적 뇌파특징 분석연구이장한, 이준석, 정규희한국임상심리학회 · Korean Journal of Clinical Psychology2008 · 제27권 제3호우울증의 뇌파변화천은진대한생물치료정신의학회 · 생물치료정신의학2013 · 제19권 제2호분노증후군과 주요우울장애의 뇌파 연구김가나, 조성훈, 지상은, 최민지대한한방신경정신과학회 · 동의신경정신과학회지2013 · 제24권 제1호정신의학에서 뇌파의 임상적 활용박영민대한신경정신의학회 · 신경정신의학2019 · 제58권 제2호

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