인체 부착형 진단기기를 위한 포텐시오스텟 개발
Development of Potentiostat for Human-Body Mounted Prtable Diagnostic Devices
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초록
개인 건강 관리에 대한 관심과 고령화 사회로 인한 POCT(Point-Of-Care testing)시장은 급속도로 발전해 가고 있다. 인체에 부착하여 사용할 수 있는 potentiostat은 혈당 측정기와 같은 장치로 제한되어 있으며, 한개의 마커만 측정이 가능하다. 본 연구에서 개발한 고감도 potentiostat은 하나의 chamber에서 다수의 마커 측정이 가능하며 실시간으로 분석 데이터 확인이 가능하다. 또한, FPGA개발을 통해 component의 수를 최소화 하여, 작은 크기(23mm by 40mm)로 potentiostat을 개발 하였다. FR-4재질을 이용하여 센서를 제작하고, 다양한 센서 패턴 중 가장 안정적인 센서 패턴을 찾았다. 또한, 신뢰성(상관계수(R2):0.94)높은 데이터를 검출하고, 낮은 검출 한계()를 갖는 휴대형 인체 부착형 potentiostat 개발을 통해 POCT 산업에 큰 영향을 미칠 것으로 예상 된다.
Abstract
The interesting thing is increasing about personal healthcare and an aging society. As a result, The POCT(Point-Of-Care Testing) market is growing rapidly. There are a variety of POCT devices, of which potentiostat is often used to measure precise components. Numerous potentiostats can be easily accessible. However, a portable potentiostat with the highly accurate sensor is not easily accessible. However, Potentiostat, which can be attached to a human body, has a limited range of measurement range. The high-sensitivity potentiostat developed in this study enables the measurement of multiple markers in the one chamber and the analysis data can be checked in real time. Also, It can be communication with a computer or smartphone by internal USB, Bluetooth or Serial port. and then The potentiostat developed the compact size (23㎜ x 40㎜) by minimizing the number of components through FPGA development. and then We checked the high reliability(correlation coefficient: 0.94) and row detection limited(20nA). We make the sensor by using FR-4 material and then We found the stable pattern in the variable sensor pattern. It can be useful change the pattern and connect to the line. Also, It doesn’t break from high elasticity. Our device will have a positive influence on POCT and potentiostat market.
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