돌발성 난청에서 발병 후 2주 이상 지연된 스테로이드 복합 치료의 이점
Benefits of Delayed Steroid Combination Treatment more than Two Weeks after Onset in Sudden Hearing Loss
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초록
Objectives: We evaluated hearing recovery rates in sudden sensorineural hearing loss (SSNHL) according to a de- lay from onset to treatment. Materials and Methods: 281 subjects with SSNHL, who received steroid combination treatment as an initial treatment, were included in this study. We divided the patients into groups of the delay from onset to treatment: ≤48 hours, ≤7 days, ≤14 days, ≤21 days, ≤30 days, and 31–60 days groups. Results: Complete recovery (CR) rates were 21.2% in ≤48 hours group, 25.3% in ≤7 days group, and 7.9% in ≤14 days group. The CR was not found in groups with treatment delayed group after 14 days. The CR rate in ≤14 days group had 0.019- fold (95% CI: 0.051–0.769) decreased odds than the ≤48 hours group. Meaningful hearing recovery (MR) rates were 36.9%–47.1% in groups that received treatment within 14 days, and those of 17.7%–21.1% were observed in groups with a delay between 14 and 30 days. Of patients with treatment delays more than 31 days, hearing recovery of any type was not found. The MR rate in ≤30 days group had 0.234-folds decreased odds than ≤48 hours group (95% CI 0.061–0.906). Conclusions: Hearing recovery rates according to the delay of initial steroid treatment in SSNHL patients were identified. Clinicians can provide patients with information for hearing outcomes of delayed initiation of steroid treatment. Shared information facilitates better making decision with regard to their treatment plan.
Abstract
Objectives: We evaluated hearing recovery rates in sudden sensorineural hearing loss (SSNHL) according to a de- lay from onset to treatment. Materials and Methods: 281 subjects with SSNHL, who received steroid combination treatment as an initial treatment, were included in this study. We divided the patients into groups of the delay from onset to treatment: ≤48 hours, ≤7 days, ≤14 days, ≤21 days, ≤30 days, and 31–60 days groups. Results: Complete recovery (CR) rates were 21.2% in ≤48 hours group, 25.3% in ≤7 days group, and 7.9% in ≤14 days group. The CR was not found in groups with treatment delayed group after 14 days. The CR rate in ≤14 days group had 0.019- fold (95% CI: 0.051–0.769) decreased odds than the ≤48 hours group. Meaningful hearing recovery (MR) rates were 36.9%–47.1% in groups that received treatment within 14 days, and those of 17.7%–21.1% were observed in groups with a delay between 14 and 30 days. Of patients with treatment delays more than 31 days, hearing recovery of any type was not found. The MR rate in ≤30 days group had 0.234-folds decreased odds than ≤48 hours group (95% CI 0.061–0.906). Conclusions: Hearing recovery rates according to the delay of initial steroid treatment in SSNHL patients were identified. Clinicians can provide patients with information for hearing outcomes of delayed initiation of steroid treatment. Shared information facilitates better making decision with regard to their treatment plan.
참고문헌 (16)
- Byl FM Jr, "Sudden hearing loss : eight years’ experience and suggested prognostic table", Laryngoscope, 94(5 Pt 1), pp.647~661 (1984)
- 강우석, "Prognostic Factors for Recovery from Sudden Sensorineural Hearing Loss: A Retrospective Study", Journal of Audiology & Otology, 21(1), pp.9~15 (2017), 대한청각학회
- Ceylan A, "Impact of prognostic factors on recovery from sudden hearing loss", J Laryngol Otol, 121(11), pp.1035~1040 (2007)
- Edizer DT, "Recovery of idiopathic sudden sensorineural hearing loss", J Int Adv Otol, 11(2), pp.122~126 (2015)
- Kuhn M, "Sudden sensorineural hearing loss : a review of diagnosis, treatment, and prognosis", Trends Amplif, 15(3), pp.91~105 (2011)
- Chandrasekhar SS, "Clinical practice guideline : sudden hearing loss(update)", Otolaryngol Head Neck Surg, 146(suppl 1), pp.S1~45 (2019)
- Čvorović L, "Prognostic model for predicting hearing recovery in idiopathic sudden sensorineural hearing loss", Otol Neurotol, 29(4), pp.464~469 (2008)
- Zadeh MH, "Diagnosis and treatment of sudden-onset sensorineural hearing loss : a study of 51 patients", Otolaryngol Head Neck Surg, 128(1), pp.92~98 (2003)
- Nosrati-Zarenoe R, "Idiopathic sudden sensorineural hearing loss : results drawn from the Swedish national database", Acta Otolaryngol, 127(11), pp.1168~1175 (2007)
- 이현수, "A Clinical Analysis of Sudden Sensorineural Hearing Loss Cases", Journal of Audiology & Otology, 18(2), pp.69~75 (2014), 대한청각학회
- Bulğurcu S, "The effects of prognostic factors in idiopathic sudden hearing loss", Int Arch Otorhinolaryngol, 22(1), pp.33~37 (2018)
- Xie Y, "Outcomes of unilateral idiopathic sudden sensorineural hearing loss : two decades of experience", Laryngoscope Investig Otolaryngol, 4(6), pp.693~702 (2019)
- Nosrati-Zarenoe R, "Corticosteroid treatment of idiopathic sudden sensorineural hearing loss : randomized triple-blind placebo-controlled trial", Otol Neurotol, 33(4), pp.523~531 (2012)
- Kyung Hyun Min, "Characteristics of Adverse Effects When Using High Dose Short Term Steroid Regimen", Journal of Audiology & Otology, 16(2), pp.65~70 (2012), 대한청각학회
- Rauch SD, "Oral vs intratympanic corticosteroid therapy for idiopathic sudden sensorineural hearing loss : a randomized trial", J Am Med Assoc, 305(20), pp.2071~2079 (2011)
- Mattox DE, "Natural history of sudden sensorineural hearing loss", Ann Otol Rhinol Laryngol, 86(4 Pt 1), pp.463~480 (1977)