돌발성 난청의 구제치료
Salvage Treatment of Sudden Sensorineural Hearing Losss
1
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
The purpose of this study was to analyze the outcome of remedial treatment for patients who had been over 2 weeks after the onset of sudden onset of hearing loss and who did not recover after the initial treatment. Subjects and Methods:Retrospective chart review was done with the patients who were diagnosed as sudden sensorineural hearing loss and visited our clinic 2 weeks after onset or not improved after receiving oral steroid treatment from January 2010 to December 2015. Twenty four patients out of 187 SSNHL were enrolled. Hearing outcomes were determined by hearing gains in pure-tone average (PTA) measured by audiometry before and 3 months after salvage therapies. Results:Significant larger hearing gains in PTA were found in the oral steroid and intratympanic injection groups than the control group. Intratympanic group resulted in a significantly larger PTA improvement than the oral steroid group (p=0.035). Conclusion:Therefore, in the case of sudden hearing loss more than 2 weeks after onse or that failed in the first treatment, it is necessary to treat either oral steroid or intratympanic injection of dexamethasone considering the general condition and the environment of the patient.
Abstract
The purpose of this study was to analyze the outcome of remedial treatment for patients who had been over 2 weeks after the onset of sudden onset of hearing loss and who did not recover after the initial treatment. Subjects and Methods:Retrospective chart review was done with the patients who were diagnosed as sudden sensorineural hearing loss and visited our clinic 2 weeks after onset or not improved after receiving oral steroid treatment from January 2010 to December 2015. Twenty four patients out of 187 SSNHL were enrolled. Hearing outcomes were determined by hearing gains in pure-tone average (PTA) measured by audiometry before and 3 months after salvage therapies. Results:Significant larger hearing gains in PTA were found in the oral steroid and intratympanic injection groups than the control group. Intratympanic group resulted in a significantly larger PTA improvement than the oral steroid group (p=0.035). Conclusion:Therefore, in the case of sudden hearing loss more than 2 weeks after onse or that failed in the first treatment, it is necessary to treat either oral steroid or intratympanic injection of dexamethasone considering the general condition and the environment of the patient.
참고문헌 (23)
- Alimoglu Y, "Is hyperbaric oxygen therapy a salvage treatment option for sudden sensorineural hearing loss?", J Laryngol Otol, 130(10), pp.943~947 (2016)
- Ahn JH, "Therapeutic effectiveness over time of intratympanic dexamethasone as salvage treatment of sudden deafness", Acta Otolaryngol, 128(2), pp.128~131 (2008)
- Crane RA, "Steroids for treatment of sudden sensorineural hearing loss: a metaanalysis of randomized controlled trials", Laryngoscope, 125(1), pp.209~217 (2015)
- 이종대, "Intratympanic Steroids in Severe to Profound Sudden Sensorineural Hearing Loss as Salvage Treatment", Clinical and Experimental Otorhinolaryngology, 3(3), pp.122~125 (2010), 대한이비인후과학회
- Nakache G, "Steroid-based treatments for patients with total sudden sensorineural hearing loss", Acta Otolaryngol, 135(9), pp.907~913 (2015)
- O’Connell BP, "Current concepts in the management of idiopathic sudden sensorineural hearing loss", Curr Opin Otolaryngol Head Neck Surg, 24(5), pp.413~419 (2016)
- Kakehata S, "Daily short-term intratympanic dexamethasone treatment alone as an initial or salvage treatment for idiopathic sudden sensorineural hearing loss", Audiol Neurootol, 16(3), pp.191~197 (2011)
- Erdur O, "Effectiveness of intratympanic dexamethasone for refractory sudden sensorineural hearing loss", Eur Arch Otorhinolaryngol, 271(6), pp.1431~1436 (2014)
- Ho HG, "Effectiveness of intratympanic dexamethasone injection in sudden-deafness patients as salvage treatment", Laryngoscope, 114(7), pp.1184~1189 (2004)
- Kawano T, "Efficacy of intratympanic steroid treatment for idiopathic sudden sensorineural hearing loss after failure of intravenous steroid treatment", Nihon Jibiinkoka Gakkai Kaiho, 117(6), pp.802~808 (2014)
- Oue S, "Efficacy of low-dose intratympanic dexamethasone as a salvage treatment for idiopathic sudden sensorineural hearing loss: the Modbury Hospital experience", J Laryngol Otol, 128(Suppl 2), pp.S27~S30 (2014)
- Liu Y, "Time of salvage treatment on sudden sensorineural hearing loss", Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi, 29(8), pp.719~722 (2014)
- Nakagawa T, "Prognostic impact of salvage treatment on hearing recovery in patients with sudden sensorineural hearing loss refractory to systemic corticosteroids:a retrospective observational study", Auris Nasus Larynx, 43(5), pp.489~494 (2016)
- Lavigne P, "Intratympanic corticosteroids injections: a systematic review of literature", Eur Arch Otorhinolaryngol, 273(9), pp.2271~2278 (2016)
- Ng JH, "Intratympanic steroids as a salvage treatment for sudden sensorineural hearing loss? A meta-analysis", Eur Arch Otorhinolaryngol, 272(10), pp.2777~2782 (2015)
- Li H, "Intratympanic steroid therapy as a salvage treatment for sudden sensorineural hearing loss after failure of conventional therapy: a meta-analysis of randomized, controlled trials", Clin Ther, 37(1), pp.178~177 (2015)
- Gunel C, "Efficacy of low-dose intratympanic dexamethasone for sudden hearing loss", Auris Nasus Larynx, 42(4), pp.284~287 (2015)
- Chou YF, "Comparison of intermittent intratympanic steroid injection and near-continual transtympanic steroid perfusion as salvage treatments for sudden sensorineural hearing loss", Laryngoscope, 123(9), pp.2264~2269 (2013)
- Yang CH, "Comparison of intratympanic steroid injection, hyperbaric oxygen and combination therapy in refractory sudden sensorineural hearing loss", Otol Neurotol, 34(8), pp.1411~1416 (2013)
- Psillas G, "Hyperbaric oxygen as salvage treatment for idiopathic sudden sensorineural hearing loss", B-ENT, 11(1), pp.39~44 (2015)
- Pezzoli M, "Hyperbaric oxygen therapy as salvage treatment for sudden sensorineural hearing loss: a prospective controlled study", Eur Arch Otorhinolaryngol, 272(7), pp.1659~1666 (2015)
- Lamm H, "Concurrent hyperbaric oxygen therapy and intratympanic steroid application as salvage therapy after severe sudden sensorineural hearing loss", Clin Case Rep, 4(3), pp.287~293 (2016)
- Gülüstan F, "Intratympanic steroid injection and hyperbaric oxygen therapy for the treatment of refractory sudden hearing loss", Braz J Otorhinolaryngol (2016)
