외상성 치매와 알쯔하이머형 치매의 신경인지기능 비교
Difference in Neurocognitive Function between the Patients with Alzheimer and Traumatic Brain Injury
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본 연구는 외상성 치매환자와 알쯔하이머형 치매 환 자의 신경인지기능을 비교하고자 하였다. DSM-IV에 의해 치매로 진단된 환자들에 대하여 MMSE, SNSB 을 사용하여 신경인지기능을 평가하였고 GDS, Barthel ADL, CDR을 사용하여 치매의 심각도, 우울정도, 일상 생활능력을 평가하였다. 그 결과 TBI 군의 신경인지심 리학적 기능은 주의집중력, 언어능력, 시공간기능, 언 어 기억력 등 광범위한 인지기능 영역에서 알쯔하이머 형 치매 군에 비하여 저조하였으며, 단지 시각기억력과 전두엽성 인지기능 및 억제기능은 명백한 차이가 나지 않았다. 이러한 전반적인 신경인지기능의 저하는 임상 적으로 병의 경과에 중요한 소견일 뿐만 아니라 환자 의 삶의 질과 관련되기 때문에, 특히 노인 환자에게 더 많은 관심이 필요할 것으로 생각된다.
Abstract
Objectives:The aim of this study was to evaluate and compare neurocognitive function between Alzheimer ’s disease and traumatic brain injury(TBI). Methods:Mini Mental State Examination(MMSE), Seoul Neuropsychological Screening Battery(SNSB), Geriatric Depression Scale(GDS), Barthel Activities of Daily Living(Barthel ADL), and Clinical Dementia Rating(CDR) was applied to compare between two groups. Results:TBI group had significant lower score than Alzheimer group in MMSE. TBI group showed lower perform ¬ance with statistical significance in attention, language and visuospatial functions. TBI group also showed signifi¬cant lower ability than Alzheimer group in memory. There was no difference in Rey Complex Figure Test between two groups. There was no significant difference in frontal/executive function. TBI group showed higher score in de¬pression, lower in living activity. Conclusion:TBI group show significant lower performance in neurocognitive function. We should pay attention to neurocognitive function, especially in elderly patient.
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