암 환자의 정신병리와 치료 목적에 대한 인지 및 삶의 질의 관계
Relationship of Psychopathology, Perception of Treatment Goal and Quality of Life in Patients with Cancer
1
조회
0
다운로드
3
인용
0
참고문헌
키워드
초록
Objectives:We evaluated the relationship of the psychopathology, quality of life and perception of treatment goal in patients with cancer. Methods:A sample of 102 cancer patients completed both Hospital Anxiety and Depression Scale(HADS) and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire C-30(EORTC QLQ C-30). We compared the differences of the psychopathology of patients according to perception of treatment goal by chi-square test and evaluated risk factors for palliative perception of treatment goal by multiple logistic regression. We exhibited t-test to compare HADS and EORTC QLQ C-30 and the association between HADS and EORTC QLQ C-30 was analyzed by Pearson correlation analysis. Results:Of 102, 25 cancer patients had the psychopathology(HAD-T ≥19), including 21 for anxiety(HAD-A ≥8), 59 for depression(HAD-D ≥8). The association between HADS and EORTC QLQ C-30 was negatively correlated with statistical significance. Patients with depression and severe psychopathology showed statistically significant tendency to perceive treatment goal as palliative. Depression and metastasis were risk factors for palliative perception of treatment goal. Conclusions:Psychopathology and quality of life in patients with cancer is important for perception of treatment goal. Assessment and intervention to improve psychological distress and quality of life is warranted during all periods of cancer treatment.
Abstract
Objectives:We evaluated the relationship of the psychopathology, quality of life and perception of treatment goal in patients with cancer. Methods:A sample of 102 cancer patients completed both Hospital Anxiety and Depression Scale(HADS) and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire C-30(EORTC QLQ C-30). We compared the differences of the psychopathology of patients according to perception of treatment goal by chi-square test and evaluated risk factors for palliative perception of treatment goal by multiple logistic regression. We exhibited t-test to compare HADS and EORTC QLQ C-30 and the association between HADS and EORTC QLQ C-30 was analyzed by Pearson correlation analysis. Results:Of 102, 25 cancer patients had the psychopathology(HAD-T ≥19), including 21 for anxiety(HAD-A ≥8), 59 for depression(HAD-D ≥8). The association between HADS and EORTC QLQ C-30 was negatively correlated with statistical significance. Patients with depression and severe psychopathology showed statistically significant tendency to perceive treatment goal as palliative. Depression and metastasis were risk factors for palliative perception of treatment goal. Conclusions:Psychopathology and quality of life in patients with cancer is important for perception of treatment goal. Assessment and intervention to improve psychological distress and quality of life is warranted during all periods of cancer treatment.
참고문헌 (40)
- Pasquini M, "Depression in cancer patients:a critical review", Clin Pract Epidemiol Ment Health, 3, pp.2~ (2007)
- 함봉진, "정신종양학의 역사와 현황", 신경정신의학, 46(5), pp.413~420 (2007), 대한신경정신의학회
- Montazeri A, "Health-related quality of life in breast cancer patients:a bibliographic review of the literature from 1974 to 2007", J Exp Clin Cancer Res, 27, pp.32~ (2008)
- Massie MJ, "Prevalence of depression in patients with cancer", pp.57~71 (2004), J Natl Cancer Inst Monogr
- Stark DP, "Anxiety in cancer patients", Br J Cancer, 83, pp.1261~1267 (2000)
- Gregurek R, "Psychological problems of patients with cancer", Psychiatr Danub, 22, pp.227~230 (2010)
- Trask PC, "Psychosocial characteristics of individuals with non-stage IV melanoma", J Clin Oncol, 19, pp.2844~2850 (2001)
- Stommel M, "Depression and functional status as predictors of death among cancer patients", Cancer, 94, pp.2719~2727 (2002)
- Bui QU, "Relationship of depression to patient satisfaction:findings from the barriers to breast cancer study", Breast Cancer Res Treat, 89, pp.23~28 (2005)
- Spiegel D, "Depression and cancer:mechanisms and disease progression", Biol Psychiatry, 54, pp.269~282 (2003)
- Morris J, "The use of quality of life data in clinical practice", Qual Life Res, 7, pp.85~91 (1998)
- Pinquart M, "Cancer patients’ perceptions of positive and negative illness-related changes", J Health Psychol, 12, pp.907~921 (2007)
- Alexander PJ, "Psychiatric morbidity among cancer patients and its relationship with awareness of illness and expectations about treatment outcome", Acta Oncol, 32, pp.623~626 (1993)
- Zigmond AS, "The hospital anxiety and depression scale", Acta Psychiatr Scand, 67, pp.361~370 (1983)
- Oh SM, "A Study on the standardization of the Hospital Anxiety and Depression Scale for Koreans:a comparison of normal,depressed and anxious groups", Journal of the Korean Neuropsychiatric Association, 38, pp.289~296 (1999)
- Hopwood P, "Screening for psychiatric morbidity in patients with advanced breast cancer:validation of two self-report questionnaires", Br J Cancer, 64, pp.353~356 (1991)
- Sollner W, "Use of complementary and alternative medicine by cancer patients is not associated with perceived distress or poor compliance with standard treatment but with active coping behavior:a survey", Cancer, 89, pp.873~880 (2000)
- Razavi D, "Screening for adjustment disorders and major depressive disorders in cancer in-patients", Br J Psychiatry, 156, pp.79~83 (1990)
- Aaronson NK, "The European Organization for Research and Treatment of Cancer QLQ-C30:a qualityof-life instrument for use in international clinical trials in oncology", J Natl Cancer Inst, 85, pp.365~376 (1993)
- Yun YH, "Validation of the Korean version of the EORTC QLQ-C30", Qual Life Res, 13, pp.863~868 (2004)
- Fayers PM, "The EORTC QLQ-C30 scoring manual: European Organisation for Research and Treatment of Cancer" (2001), Brussels
- Zabora J, "The prevalence of psychological distress by cancer site", Psychooncology, 10, pp.19~28 (2001)
- Aass N, "Prevalence of anxiety and depression in cancer patients seen at the Norwegian Radium Hospital", Eur J Cancer, 33, pp.1597~604 (1997)
- Strong V, "Emotional distress in cancer patients:the Edinburgh Cancer Centre symptom study", Br J Cancer, 96, pp.868~874 (2007)
- Spiegel D, "Mind matters.Coping and cancer progression", J Psychosom Res, 50, pp.287~290 (2001)
- Kenne Sarenmalm E, "Coping with recurrent breast cancer:predictors of distressing symptoms and health-related quality of life", J Pain Symptom Manage, 34, pp.24~39 (2007)
- Groenvold M, "Psychological distress and fatigue predicted recurrence and survival in primary breast cancer patients", Breast Cancer Res Treat, 105, pp.209~19 (2007)
- Golden-Kreutz DM, "Traumatic stress,perceived global stress,and life events:prospectively predicting quality of life in breast cancer patients", Health Psychol, 24, pp.288~296 (2005)
- Dalton SO, "Depression and cancer risk: a registerbased study of patients hospitalized with affective disorders, Denmark, 1969-1993", Am J Epidemiol, 155, pp.1088~1095 (2002)
- Dalton SO, "Mind and cancer. do psychological factors cause cancer", Eur J Cancer, 38, pp.1313~1323 (2002)
- Holland JC, "American Cancer Society Award lecture. Psychological care of patients: psycho-oncology’s contribution", J Clin Oncol, 21(23 Suppl), pp.253s~255s (2003)
- Mystakidou K, "Assessment of anxiety and depression in advanced cancer patients and their relationship with quality of life", Qual Life Res, 14, pp.1825~1833 (2005)
- Ringdal GI, "Testing the EORTC Quality of Life Questionnaire on cancer patients with heterogeneous diagnoses", Qual Life Res, 2, pp.129~140 (1993)
- Grassi L, "Depressive symptoms and quality of life in home-care-assisted cancer patients", J Pain Symptom Manage, 12, pp.300~307 (1996)
- Beadle GF, "Illusions in advanced cancer:the effect of belief systems and attitudes on quality of life", Psychooncology, 13, pp.26~36 (2004)
- Taylor SE, "Illusion and well-being:a social psychological perspective on mental health", Psychol Bull, 103, pp.193~210 (1988)
- Scharloo M, "Quality of life and illness perceptions in patients with recently diagnosed head and neck cancer", Head Neck, 27, pp.857~863 (2005)
- Greer S, "Psychological response to breast cancer:effect on outcome", Lancet, 2, pp.785~787 (1979)
- Pettingale KW, "Mental attitudes to cancer:an additional prognostic factor", Lancet, 1, pp.750~ (1985)
- Herrmann C, "International experiences with the Hospital Anxiety and Depression Scale--a review of validation data and clinical results", J Psychosom Res, 2, pp.17~41 (1997)
