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알쯔하이머형 치매에서 한국판 보스톤 이름대기검사와 지연회상검사 조합의 진단적 유용성

Clinical Usefulness of Combined Korean Boston Naming Test and Delayed Recall Test in Diagnosing Dementia of the Alzheimer’s Type

구본훈|김진성|이준엽|이종범|차영
대한생물치료정신의학회 (Korean Society Of Biological Therapies In Psychiatry)|2011.06|생물치료정신의학 (Journal of the Korean Society of Biological Therapies in Psychiatry)|제17권 제1호|pp. 30-37

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키워드

알쯔하이머형 치매·한국판 보스톤 이름대기 검사·지연회상검사·민감도·특이도.
주제분류정신과학

초록

Objectives：The purpose of this study was to establish that Korean Boston Naming Test(K-BNT) and the delayed recall test of Seoul Verbal Learning Test(SVLT) applied together may be useful for clinician to diagnose dementia of the Alzheimer’s type(DAT). Methods：We compared the results of K-BNT and the delayed recall test of SVLT between DAT group(N=30) and control group(N=30) without any cognitive impairment. Also, we made Receiver Operating Characteristic Curve(ROC curve) of K-BNT and the delayed recall test of SVLT for the two groups. Results：The scores of K-BNT and the delayed recall test of SVLT of patients group with DAT were significantly lower than those of control group. K-BNT and the delayed recall test of SVLT showed the positive correlation with K-MMSE. The cut-off values of K-BNT and the delayed recall test of SVLT determined by ROC curve were z=-0.58 score (28.10‰) and z=-1.35 score(8.86‰), respectively. The sensitivities and specificities of K-BNT and the delayed recall of SVLT in order to diagnose DAT were 63.3% vs 90.0% and 73.0% vs 73.0%, respectively. When these two tests ap-plied together, the sensitivity and specificity were 50.0% and 100%. Conclusion：This study is suggested that the use of these two tests at the same time may be the useful screening test to diagnose DAT.

Abstract

Objectives：The purpose of this study was to establish that Korean Boston Naming Test(K-BNT) and the delayed recall test of Seoul Verbal Learning Test(SVLT) applied together may be useful for clinician to diagnose dementia of the Alzheimer’s type(DAT). Methods：We compared the results of K-BNT and the delayed recall test of SVLT between DAT group(N=30) and control group(N=30) without any cognitive impairment. Also, we made Receiver Operating Characteristic Curve(ROC curve) of K-BNT and the delayed recall test of SVLT for the two groups. Results：The scores of K-BNT and the delayed recall test of SVLT of patients group with DAT were significantly lower than those of control group. K-BNT and the delayed recall test of SVLT showed the positive correlation with K-MMSE. The cut-off values of K-BNT and the delayed recall test of SVLT determined by ROC curve were z=-0.58 score (28.10‰) and z=-1.35 score(8.86‰), respectively. The sensitivities and specificities of K-BNT and the delayed recall of SVLT in order to diagnose DAT were 63.3% vs 90.0% and 73.0% vs 73.0%, respectively. When these two tests ap-plied together, the sensitivity and specificity were 50.0% and 100%. Conclusion：This study is suggested that the use of these two tests at the same time may be the useful screening test to diagnose DAT.

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