Management of Laryngopharyngeal Reflux in Asia
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Objectives. This study was conducted to investigate the current practices of Asian otolaryngologists for laryngopharyngeal reflux (LPR). Methods. An online survey about LPR was sent to 2,000 members of Asian otolaryngological societies, and a subgroup analysis was performed between Western and Eastern Asian otolaryngologists. The survey was conducted by the Laryngopharyngeal Reflux Study Group of Young Otolaryngologists of the International Federation of Oto-rhino-laryngological Societies. Results. Among approximately 1,600 Asian otolaryngologists, 146 completed the survey (62 from Western Asian countries, 84 from Eastern Asian countries). A substantial majority (73.3%) of the otolaryngologists considered LPR and gastroesophageal reflux disease to be different diseases. The symptoms thought to be closely related to LPR were coughing after lying down, throat clearing, and globus sensation. The findings thought to be closely related to LPR were posterior commissure granulations and hypertrophy, arytenoids, and laryngeal erythema. The respondents indicated that they mostly diagnosed LPR (70%) after an empirical therapeutic trial of proton pump inhibitors (PPIs). Although multichannel intraluminal impedance-pH (MII-pH) monitoring is a useful tool for diagnosing nonacid or mixed LPR, 78% of Asian otolaryngologists never or very rarely used MII-pH. Eastern Asian otolaryngologists more frequently used once-daily PPIs (64.3% vs. 45.2%, P=0.021), whereas Western Asian otolaryngologists preferred to use twice-daily PPIs (58.1% vs. 39.3%, P=0.025). The poor dietary habits of patients were considered to be the main reason for therapeutic failure by Asian otolaryngologists (53.8%). Only 48.6% of Asian otolaryngologists considered themselves to be adequately knowledgeable and skilled regarding LPR. Conclusion. Significant differences exist between Western and Eastern Asian otolaryngologists in the diagnosis and treatment of LPR. Future consensus statements are needed to establish diagnostic criteria and therapeutic regimens.
Abstract
Objectives. This study was conducted to investigate the current practices of Asian otolaryngologists for laryngopharyngeal reflux (LPR). Methods. An online survey about LPR was sent to 2,000 members of Asian otolaryngological societies, and a subgroup analysis was performed between Western and Eastern Asian otolaryngologists. The survey was conducted by the Laryngopharyngeal Reflux Study Group of Young Otolaryngologists of the International Federation of Oto-rhino-laryngological Societies. Results. Among approximately 1,600 Asian otolaryngologists, 146 completed the survey (62 from Western Asian countries, 84 from Eastern Asian countries). A substantial majority (73.3%) of the otolaryngologists considered LPR and gastroesophageal reflux disease to be different diseases. The symptoms thought to be closely related to LPR were coughing after lying down, throat clearing, and globus sensation. The findings thought to be closely related to LPR were posterior commissure granulations and hypertrophy, arytenoids, and laryngeal erythema. The respondents indicated that they mostly diagnosed LPR (70%) after an empirical therapeutic trial of proton pump inhibitors (PPIs). Although multichannel intraluminal impedance-pH (MII-pH) monitoring is a useful tool for diagnosing nonacid or mixed LPR, 78% of Asian otolaryngologists never or very rarely used MII-pH. Eastern Asian otolaryngologists more frequently used once-daily PPIs (64.3% vs. 45.2%, P=0.021), whereas Western Asian otolaryngologists preferred to use twice-daily PPIs (58.1% vs. 39.3%, P=0.025). The poor dietary habits of patients were considered to be the main reason for therapeutic failure by Asian otolaryngologists (53.8%). Only 48.6% of Asian otolaryngologists considered themselves to be adequately knowledgeable and skilled regarding LPR. Conclusion. Significant differences exist between Western and Eastern Asian otolaryngologists in the diagnosis and treatment of LPR. Future consensus statements are needed to establish diagnostic criteria and therapeutic regimens.
참고문헌 (38)
- Lechien JR, "Clinical outcomes of laryngopharyngeal reflux treatment : a systematic review and meta-analysis", Laryngoscope, 129(5), pp.1174~1187 (2019)
- Mosli M, "Prevalence and clinical predictors of LPR among patients diagnosed with GERD according to the reflux symptom index questionnaire", Saudi J Gastroenterol, 24(4), pp.236~241 (2018)
- Koufman JA, "Laryngopharyngeal reflux : position statement of the committee on speech, voice, and swallowing disorders of the American Academy of Otolaryngology-Head and Neck Surgery", Otolaryngol Head Neck Surg, 127(1), pp.32~35 (2002)
- Eusebi LH, "Global prevalence of, and risk factors for, gastro-oesophageal reflux symptoms : a meta-analysis", Gut, 67(3), pp.430~440 (2018)
- Kamani T, "The prevalence of laryngopharyngeal reflux in the English population", Eur Arch Otorhinolaryngol, 269(10), pp.2219~2225 (2012)
- Spantideas N, "Laryngopharyngeal reflux disease in the Greek general population, prevalence and risk factors", BMC Ear Nose Throat Disord, 15, pp.7~ (2015)
- Chen XM, "Prevalence of laryngopharyngeal reflux disease in Fuzhou region of China", Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi, 51(12), pp.909~913 (2016)
- Kim SI, "Association between 24-hour combined multichannel intraluminal impedance-pH monitoring and symptoms or quality of life in patients with laryngopharyngeal reflux", Clin Otolaryngol, 42(3), pp.584~591 (2017)
- Lechien JR, "Evaluation and management of laryngopharyngeal reflux disease : state of the art review", Otolaryngol Head Neck Surg, 160(5), pp.762~782 (2019)
- Gupta N, "Evaluation of a laryngopharyngeal reflux management protocol", Am J Otolaryngol, 37(3), pp.245~250 (2016)
- Altman KW, "Changing impact of gastroesophageal reflux in medical and otolaryngology practice", Laryngoscope, 115(7), pp.1145~1153 (2005)
- Johnston N, "Airway reflux", Ann N Y Acad Sci, 1381(1), pp.5~13 (2016)
- Lechien JR, "Validity and reliability of the reflux symptom score", Laryngoscope, 130(3), pp.E98~E107 (2020)
- Koufman JA, "The otolaryngologic manifestations of gastroesophageal reflux disease (GERD): a clinical investigation of 225 patients using ambulatory 24-hour pH monitoring and an experimental investigation of the role of acid and pepsin in the development of laryngeal injury", Laryngoscope, 101(4 Pt 2 Suppl 53), pp.1~78 (1991)
- Lechien JR, "Awareness of European otolaryngologists and general practitioners toward laryngopharyngeal reflux", Ann Otol Rhinol Laryngol, 128(11), pp.1030~1040 (2019)
- Michaudet C, "Chronic cough : evaluation and management", Am Fam Physician, 96(9), pp.575~580 (2017)
- Wang JS, "The role of laryngopharyngeal reflux in the pathogenesis of Reinke’s edema", Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi, 30(24), pp.1931~1934 (2016)
- Alanazi R, "Association between voice handicap index and reflux symptom index : a cross-sectional study of undiagnosed general and teacher cohorts in Saudi Arabia", Sultan Qaboos Univ Med J, 18(3), pp.e350~e354 (2018)
- Lechien JR, "Change of signs, symptoms and voice quality evaluations throughout a 3-to 6-month empirical treatment for laryngopharyngeal reflux disease", Clin Otolaryngol, 43(5), pp.1273~1282 (2018)
- Jiang SP, "Effects of antireflux treatment on bronchial hyper-responsiveness and lung function in asthmatic patients with gastroesophageal reflux disease", World J Gastroenterol, 9(5), pp.1123~1125 (2003)
- Miura MS, "Association between otitis media and gastroesophageal reflux : a systematic review", Otolaryngol Head Neck Surg, 146(3), pp.345~352 (2012)
- Al-Saab F, "Linking laryngopharyngeal reflux to otitis media with effusion : pepsinogen study of adenoid tissue and middle ear fluid", J Otolaryngol Head Neck Surg, 37(4), pp.565~571 (2008)
- Lechien JR, "Association between laryngopharyngeal reflux and benign vocal folds lesions : a systematic review", Laryngoscope, 129(9), pp.E329~E341 (2019)
- Toohill RJ, "Evaluation of gastroesophageal reflux in patients with laryngotracheal stenosis", Ann Otol Rhinol Laryngol, 107(12), pp.1010~1014 (1998)
- Loehrl TA, "The role of extraesophageal reflux in medically and surgically refractory rhinosinusitis", Laryngoscope, 122(7), pp.1425~1430 (2012)
- Lee YC, "Do laryngoscopic findings reflect the characteristics of reflux in patients with laryngopharyngeal reflux?", Clin Otolaryngol, 43(1), pp.137~143 (2018)
- Chang BA, "The reliability of the reflux finding score among general otolaryngologists", J Voice, 29(5), pp.572~577 (2015)
- Koufman JA, "Laryngopharyngeal reflux is different from classic gastroesophageal reflux disease", Ear Nose Throat J, 81(9 Suppl 2), pp.7~9 (2002)
- Jaspersen D, "Prevalence of extra-oesophageal manifestations in gastro-oesophageal reflux disease : an analysis based on the ProGERD Study", Aliment Pharmacol Ther, 17(12), pp.1515~1520 (2003)
- Patel D, "Normal esophageal physiology and laryngopharyngeal reflux", Otolaryngol Clin North Am, 46(6), pp.1023~1041 (2013)
- Guo H, "Proton pump inhibitor therapy for the treatment of laryngopharyngeal reflux : a meta-analysis of randomized controlled trials", J Clin Gastroenterol, 50(4), pp.295~300 (2016)
- Park W, "Laryngopharyngeal reflux : prospective cohort study evaluating optimal dose of proton-pump inhibitor therapy and pretherapy predictors of response", Laryngoscope, 115(7), pp.1230~1238 (2005)
- Yoon YH, "Efficacy of three proton-pump inhibitor therapeutic strategies on laryngopharyngeal reflux disease; a prospective randomized double-blind study", Clin Otolaryngol, 44(4), pp.612~618 (2019)
- Postma GN, "Treatment of laryngopharyngeal reflux", Ear Nose Throat J, 81(9 Suppl 2), pp.24~26 (2002)
- Koufman JA, "Low-acid diet for recalcitrant laryngopharyngeal reflux : therapeutic benefits and their implications", Ann Otol Rhinol Laryngol, 120(5), pp.281~287 (2011)
- Zalvan CH, "A comparison of alkaline water and Mediterranean diet vs proton pump inhibition for treatment of laryngopharyngeal reflux", JAMA Otolaryngol Head Neck Surg, 143(10), pp.1023~1029 (2017)
- Lechien JR, "Alkaline, protein, low-fat and low-acid diet in laryngopharyngeal reflux disease : our experience on 65 patients", Clin Otolaryngol, 44(3), pp.379~384 (2019)
- Pisegna JM, "A mixed-methods study of patient views on reflux symptoms and medication routines", J Voice, 31(3), pp.381~ (2017)