안와 고립성 섬유종
A Case of Solitary Fibrous Tumor of Orbit
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목적: 안와에서 발생하는 고립성섬유종은 중배엽 기원의 드문 안와종양으로 다른 안와 종양들과 감별이 필요하며, 정확한 진단을 위해서는 면역조직화학검사가 중요하다. 안와연부조직에서 발생한 고립성섬유종은 국내에서는 발표된 적이 없으며, 본 증례를 통해 고립성 섬유종이 눈물샘 뿐만 아니라 안와 연부 조직에서도 발생할 수 있음을 저자들은 문헌고찰과 함께 보고하는 바이다. 증례요약: 50세 남자환자가 1년 전부터 좌측 아래눈꺼풀 외측에서 서서히 진행하는 종괴를 주소로 내원하였다. 통증이나 분비물 및기타 종괴로 인한 압박 증상은 없었고 세극등검사를 비롯한 안과검사는 특별한 이상이 없었다. 안와부 자기공명영상에서 균일하게조영증강이 되는 13x11 mm 종괴가 관찰되었다. 환자는 종괴제거를 위해 국소마취하 전절제술을 시행하였으며, 면역조직화학적 검사에서 CD 34에 대해 양성으로, 이는 고립성 섬유종에 합당하는 소견이었다. 결론: 고립성 섬유종은 안와에서 발생하는 드문 종양으로 여러 안와 종양과 감별이 필요한 질환이다.
Abstract
Purpose: A Solitary fibrous tumor is a rare orbital neoplasm derived from mesenchymal cells. The neoplasm should be considered in differential diagnosis of any orbital tumor, and immunohistochemial analysis is important for correct diagnosis. The authors herein describe a case of a solitary fibrous tumor in addition to the findings of a literature review. Solitary fibrous tumors can develop from not only the lacrimal gland, but also orbital soft tissue. Until now, there has been no report of a solitary fibrous tumor arising from orbital soft tissue in Korea. Case summary: A 50-year-old man visited our clinic due to a slow progressing mass on the lateral side of the left eye for 1year. The patient did not suffer from any discomfort or discharge from the mass. Slit lamp and other ocular examinations were unremarkable. Orbital MRI revealed a solid extra-conal enhanced mass that measured 13x11 mm adhering to the lateral wall of the left orbit. Total surgical excision was Performed under local anesthesia and tumor cells showed a strong and diffuse positivity for CD34 by immunohistochemistry. The findings were consistent with the diagnosis of orbital solitary tumor. Conclusions: The orbital solitary tumor is rare, but it should be considered in the differential diagnosis of any orbital tumor.
참고문헌 (11)
- Bernardini FP, "Solitary fibrous tumor of the orbit. Is it rare? Report of a case series and review of the literature", Ophthalmology, 110, pp.1442~1448 (2003)
- Leoncini G, "Orbital Solitary Fibrous tumor. A case report and review of the literature", Pathol Oncol Res, 14, pp.213~217 (2008)
- Schellini SA, "Orbital Solitary Fibrous Tumor: Report of Two Cases and Literature Review", Jpn J Ophthalmol, 47, pp.415~418 (2003)
- Das JK, "Solitary fibrous tumor of the orbit presenting in pregnancy", Indian J Ophthalmol, 57, pp.238~240 (2009)
- Pitchamuthu H, "Fat-forming variant of solitary fibrous tumour of the orbit : the entity previously known as lipomatous haemangiopericytoma", Eye, 23, pp.1479~1481 (2009)
- Lee NH, "A case of Solitary fibrous tumor of lacrimal gland", J Korean Ophthalmol, 41, pp.2258~2262 (2000)
- Kang YK, "Malignant solitary fibrous tumor of the pleura in mediastinum", Korean J Pathol, 31, pp.351~356 (1997)
- Westra WH, "Solitary fibrous tumor. Consistent CD34 immunoreactivity and occurrence in the orbit", Am J Surg Pathol, 18, pp.992~998 (1994)
- Lee JH, "Surgical therapy of solitary fibrous tumor of the parietal pleura", Korean Society for Thoracic and Cardiovascular Surgery, 29, pp.798~801 (1996)
- Dorfman DM, "Solitary fibrous tumor of the orbit", Am J Surg Pathol, 18, pp.281~287 (1994)
- Cho NH, "Solitary fibrous tumor with an unusual adenofibromatous feature in the lacrimal gland", Histopathology, 33, pp.289~901 (1998)