Comparison of Choroidal Thickness in Patients with Diabetes by Spectral-domain Optical Coherence Tomography
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Purpose: To evaluate choroidal thickness in diabetes patients using spectral-domain optical coherence tomography. Methods: We examined 203 eyes of 203 diabetic participants and 48 eyes of 48 healthy controls. The choroidalthickness at the foveal lesion was measured by enhanced-depth imaging optical coherence tomography. Theparticipants were grouped according to diabetic retinopathy grade: no diabetic change, mild-to-moderate orsevere non-proliferative, or proliferative diabetic retinopathy. The study parameters included history, age, axiallength, intraocular pressure, central retinal thickness, fasting glucose, and blood pressure. Results: The subfoveal choroidal thickness was thinner in eyes with non-proliferative or proliferative diabetic retinopathythan in normal eyes (p < 0.01). However, there was no difference between eyes with non-proliferativeand proliferative diabetic retinopathy or between eyes with no diabetic change and the controls. Eyes exhibitingmacular edema showed no significant difference in choroidal thickness compared with eyes having normalmacular contours. Conclusions: The central choroid is thinner when eyes show diabetic changes on the retina. However, thepresence of diabetic macular edema or proliferative change is not associated with more pronounced choroidalthinning.
Abstract
Purpose: To evaluate choroidal thickness in diabetes patients using spectral-domain optical coherence tomography. Methods: We examined 203 eyes of 203 diabetic participants and 48 eyes of 48 healthy controls. The choroidalthickness at the foveal lesion was measured by enhanced-depth imaging optical coherence tomography. Theparticipants were grouped according to diabetic retinopathy grade: no diabetic change, mild-to-moderate orsevere non-proliferative, or proliferative diabetic retinopathy. The study parameters included history, age, axiallength, intraocular pressure, central retinal thickness, fasting glucose, and blood pressure. Results: The subfoveal choroidal thickness was thinner in eyes with non-proliferative or proliferative diabetic retinopathythan in normal eyes (p < 0.01). However, there was no difference between eyes with non-proliferativeand proliferative diabetic retinopathy or between eyes with no diabetic change and the controls. Eyes exhibitingmacular edema showed no significant difference in choroidal thickness compared with eyes having normalmacular contours. Conclusions: The central choroid is thinner when eyes show diabetic changes on the retina. However, thepresence of diabetic macular edema or proliferative change is not associated with more pronounced choroidalthinning.
참고문헌 (27)
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