건성안 환자의 광학적 특성에 대한 객관적인 분석
Objective Optical Quality Analysis in Dry Eye Syndrome
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목적: 건성안 환자에서 객관적 시력의 질 평가에 있어 OQASⓇ 장비의 효용성을 알아보고자 하였다. 대상과 방법: 건성안 환자 20명과 정상 대조군 20명을 대상으로 Optical Quality Analysis System (OQASⓇ) 연속측정 방법을 사용하여 눈 깜박임 후 20초 동안의 변화를 측정하였다. 결과: 20초 동안 매초 측정된 Objective Scatter Index (OSI)의 평균값은 건성안에서 4.53, 정상안에서는 0.67이고, 개인의 OSI 값의편차는 건성안에서 1.20, 정상안에서 1.18로 건성안 군에서 OSI의 평균과 편차가 모두 유의하게 높았다. 두 군 모두 시간이 경과할수록OSI 값이 증가하는 양상을 보였고, 눈 깜박임 후 13.5초가 경과한 시점에서 최초 측정된 값과 유의한 차이를 나타냈다. 20초 동안의변화량은 건성안에서 4.15, 정상안에서 0.32로 건성안에서 통계학적으로 유의하게 높았다. 결론: 눈 깜박임 후 시간에 따라 OSI 값은 증가하며, 건성안 환자에서는 높은 OSI와 큰 변이도를 나타냈다. 따라서 건성안 환자에서시력의 질 저하의 평가에 OQAS® 연속측정이 유용할 것으로 생각한다.
Abstract
Purpose: To evaluate the efficacy of Optical Quality Analysis System (OQASⓇ) instrument for the assessment of dry eyesyndrome. Methods: Dynamic recording of double-pass (DP) retinal images was performed in 1 eye dry eye patients (20 eyes) and inhealthy controls (20 eyes) for 20 seconds after eye blinking. Results: The mean objective scatter Index (OSI) value was 4.53 in dry eyes, 0.67 in healthy eyes and the standard deviation ofOSI was 1.20 in dry eyes and 1.18 in healthy eyes. The patients with dry eyes showed significantly higher mean OSI and standarddeviation values. Ocular scatter increased over time and significant changes occurred 13.5 seconds after blinking. The differencein OSI value between 0 second and 20 seconds was significantly greater in dry eye patients (4.15) than in controls (0.32). Conclusions: Ocular scatter increased over time after blinking. The dry eye patients had larger and more variable ocular scatterindex than the controls. OQASⓇ may be useful to detect and follow-up tear film-related patient complaints in dry eye syndrome.
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