Effects of Multicurve RGP Contact Lens Use on Topographic Changes in Keratoconus
2
조회
0
다운로드
2
인용
0
참고문헌
키워드
초록
Purpose: To evaluate the effects of wearing rigid gas permeable (RGP) contact lenses on the topographic changes in keratoconus. Methods: Seventy-seven keratoconic eyes that wore multicurve RGP contact lenses and 30 keratoconic eyes that wore no contact lenses were retrospectively analyzed. The mean follow-ups were 22.6 and 20.5 months in the lens-wearing and control groups, respectively. Visual acuity, comfort, daily wearing time, and corneal staining were evaluated for both groups. The changes in topographic indices were compared between the lens-wearing and control groups. Results: Multicurve RGP lens corrected logarithm of the minimum angle of resolution visual acuity of the lens-wearing group significantly improved from -0.016±0.065 to -0.032±0.10 at follow-up (p=0.05). In the lens-wearing group with advanced keratoconus, the Sim Kmax, Sim Kmin, apical power, astigmatic index, and anterior elevation significantly decreased from 57.68±4.26 diopter (D), 50.50±2.32 D, 62.79±5.11 D, 7.20±0.55 D and 67.36±16.30 μm to 55.51±4.28 D, 49.62±3.26 D, 60.31±5.41 D, 5.90±0.51 D and 60.61±16.09 μm, respectively (paired t-test, p<0.05). The irregularity index of 3 mm did not significantly change. Meanwhile, in the control group, the apical power and irregularity index increased from 55.56±7.25 D and 3.06±1.68 D to 57.11±7.75 D and 3.25±1.71 D, respectively (paired t-test, p=0.008, p=0.01). Conclusions: Properly fitted multicurve RGP contact lenses are not likely to contribute to the progression of keratoconus.
Abstract
Purpose: To evaluate the effects of wearing rigid gas permeable (RGP) contact lenses on the topographic changes in keratoconus. Methods: Seventy-seven keratoconic eyes that wore multicurve RGP contact lenses and 30 keratoconic eyes that wore no contact lenses were retrospectively analyzed. The mean follow-ups were 22.6 and 20.5 months in the lens-wearing and control groups, respectively. Visual acuity, comfort, daily wearing time, and corneal staining were evaluated for both groups. The changes in topographic indices were compared between the lens-wearing and control groups. Results: Multicurve RGP lens corrected logarithm of the minimum angle of resolution visual acuity of the lens-wearing group significantly improved from -0.016±0.065 to -0.032±0.10 at follow-up (p=0.05). In the lens-wearing group with advanced keratoconus, the Sim Kmax, Sim Kmin, apical power, astigmatic index, and anterior elevation significantly decreased from 57.68±4.26 diopter (D), 50.50±2.32 D, 62.79±5.11 D, 7.20±0.55 D and 67.36±16.30 μm to 55.51±4.28 D, 49.62±3.26 D, 60.31±5.41 D, 5.90±0.51 D and 60.61±16.09 μm, respectively (paired t-test, p<0.05). The irregularity index of 3 mm did not significantly change. Meanwhile, in the control group, the apical power and irregularity index increased from 55.56±7.25 D and 3.06±1.68 D to 57.11±7.75 D and 3.25±1.71 D, respectively (paired t-test, p=0.008, p=0.01). Conclusions: Properly fitted multicurve RGP contact lenses are not likely to contribute to the progression of keratoconus.
참고문헌 (29)
- Krachmer JH, "Keratoconus and related noninflammatory corneal thinning disorders", Surv Ophthalmol, 28, pp.293~322 (1984)
- Macsai MS, "Development of keratoconus after contact lens wear: patient characteristics", Arch Ophthalmol, 108, pp.534~538 (1990)
- Korb DR, "Apical changes and scarring in keratoconus as related to contact lens fitting techniques", J Am Optom Assoc, 53, pp.199~205 (1982)
- Kenney MC, "Increased levels of catalase and cathepsin V", L2 but decreased TIMP-1 in keratoconus corneas: evidence that oxidative stress plays a role in this disorder, 2005, pp.46, 823~832
- Zhou L, "Expression of degradative enzymes and protease inhibitors in corneas with keratoconus", Invest Ophthalmol Vis Sci, 39, pp.1117~1124 (1998)
- Wilson SE, "Keratocyte apoptosis: implications on corneal wound healing, tissue organization, and disease", Invest Ophthalmol Vis Sci, 39, pp.220~226 (1998)
- Buxton JN, "The contact lens correction of keratoconus. In:Contact lenses: the CLAO guide to basic science and clinical practice", pp.1~55 (1984), Grune & Stratton
- Lee JL, "Clinical performance and fitting characteristics with a multicurve lens for keratoconus", Eye Contact Lens, 30, pp.20~24 (2004)
- Efron N, "Validation of grading scales for contact lens complications", Ophthalmic Physiol Opt, 21, pp.17~29 (2001)
- Cairns G, "Orbscan computerized topography: attributes, applications, and limitations", J Cataract Refract Surg, 31, pp.205~220 (2005)
- Lim L, "Evaluation of keratoconus in Asians: role of Orbscan II and Tomey TMS-2 corneal topography", Am J Ophthalmol, 143, pp.390~400 (2007)
- Rao SN, "Role of Orbscan II in screening keratoconus suspects before refractive corneal surgery", Ophthalmology, 109, pp.1642~1646 (2002)
- Szczotka LB, "Comparison of axial and instantaneous videokeratographic data in keratoconus and utility in contact lens curvature prediction", CLAO J, 24, pp.22~28 (1998)
- McMahon TT, "Precision of three topography instruments in keratoconus subjects", Optom Vis Sci, 78, pp.599~604 (2001)
- Demirbas NH, "Topographic pattern and apex location of keratoconus on elevation topography maps", Cornea, 17, pp.476~484 (1998)
- Bessho K, "Automated keratoconus detection using height data of anterior and posterior corneal surfaces", Jpn J Ophthalmol, 50, pp.409~416 (2006)
- Tanabe T, "Standardized color-coded scales for anterior and posterior elevation maps of scanning slit corneal topography", Ophthalmology, 109, pp.1298~1302 (2002)
- Fam HB, "Corneal elevation indices in normal and keratoconic eyes", J Cataract Refract Surg, 32, pp.1281~1287 (2006)
- Sonmez B, "Identification of scanning slit-beam topographic parameters important in distinguishing normal from keratoconic corneal morphologic features", Am J Ophthalmol, 143, pp.401~408 (2007)
- Gherghel D, "Corneal pachymetry in normal and keratoconic eyes: Orbscan II versus ultrasound", J Cataract Refract Surg, 30, pp.1272~1277 (2004)
- Edrington TB, "Rigid contact lens fitting relationships in keratoconus: Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study Group", Optom Vis Sci, 76, pp.692~699 (1999)
- Mannis MJ, "Contact lens fitting in keratoconus", CLAO J, 15, pp.282~289 (1989)
- McMonnies CW, "Keratoconus fittings: apical clearance or apical support?", Eye Contact Lens, 30, pp.147~155 (2004)
- Mandell RB, "Contemporary management of keratoconus", Int Contact Lens Clin, 24, pp.43~58 (1997)
- Maguire LJ, "Identifying progression of subclinical keratoconus by serial topography analysis", Am J Ophthalmol, 112, pp.41~45 (1991)
- Smolek MK, "Cinemakeratography using computer morphing", Optom Vis Sci, 74, pp.970~975 (1997)
- McMahon TT, "A new method for grading the severity of keratoconus: the Keratoconus Severity Score (KSS)", Cornea, 25, pp.794~800 (2006)
- Kim WJ, "Changes in corneal morphology associated with chronic epithelial injury", Invest Ophthalmol Vis Sci, 40, pp.35~42 (1999)
- McMahon TT, "Longitudinal changes in corneal curvature in keratoconus", Cornea, 25, pp.296~305 (2006)