Study for Analysis of the Multifocal Visual Evoked Potential
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초록
Purpose: To introduce the clinical utility of the absolute value of the reconstructed waveform method in the analysis of multifocal visual evoked potential (mfVEP). Methods: The mfVEP with 4-channel recording was performed using RETIscan^Ⓡ on 10 eyes of 10 normal subjects. Amplitudes were obtained from ring-shaped 6 areas and 4 sectors. The best visual evoked potential (VEP) response method and the absolute value of the reconstructed waveform method were compared in terms of analysis of the amplitudes. In order to assess the false positive rate of the examination, stimuli were administered with one-half of the cathode ray tube (CRT) monitor completely covered and the results were compared using 2 methods. Results: The amplitudes in 6 areas and 4 sectors analyzed with the best VEP response method and the absolute value of the reconstructed waveform method showed no statistical difference (p > 0.05). The amplitude in the stimuli-blocked area of the absolute value of the reconstructed waveform method was smaller than that of the best VEP response method (p < 0.05) and the amplitude of the stimuli area showed no substantial difference between two methods (p > 0.05). Conclusions: The absolute value of the reconstructed waveform method has similar reproducibility and lower level of false positives relative to the best VEP response method. Therefore, it can be considered as a useful method in the analysis of the mfVEP.
Abstract
Purpose: To introduce the clinical utility of the absolute value of the reconstructed waveform method in the analysis of multifocal visual evoked potential (mfVEP). Methods: The mfVEP with 4-channel recording was performed using RETIscan^Ⓡ on 10 eyes of 10 normal subjects. Amplitudes were obtained from ring-shaped 6 areas and 4 sectors. The best visual evoked potential (VEP) response method and the absolute value of the reconstructed waveform method were compared in terms of analysis of the amplitudes. In order to assess the false positive rate of the examination, stimuli were administered with one-half of the cathode ray tube (CRT) monitor completely covered and the results were compared using 2 methods. Results: The amplitudes in 6 areas and 4 sectors analyzed with the best VEP response method and the absolute value of the reconstructed waveform method showed no statistical difference (p > 0.05). The amplitude in the stimuli-blocked area of the absolute value of the reconstructed waveform method was smaller than that of the best VEP response method (p < 0.05) and the amplitude of the stimuli area showed no substantial difference between two methods (p > 0.05). Conclusions: The absolute value of the reconstructed waveform method has similar reproducibility and lower level of false positives relative to the best VEP response method. Therefore, it can be considered as a useful method in the analysis of the mfVEP.
참고문헌 (23)
- Sutter EE, "Imaging visual function with the multifocal m-sequence technique", Vision Res, 41, pp.1241~1255 (2001)
- Hood DC, "An interocular comparison of the multifocal VEP:a possible technique for detecting local damage to the optic nerve", Invest Ophthalmol Vis Sci, 41, pp.1580~1587 (2000)
- Graham SL, "Objective VEP perimetry in glaucoma:asymmetry analysis to identify early deficits", J Glaucoma, 9, pp.10~19 (2000)
- Hood DC, "Tracking the recovery of local optic nerve function after optic neuritis:a multifocal VEP study", Invest Ophthalmol Vis Sci, 41, pp.4032~4038 (2000)
- 2001, "Comparison of threshold and multifocal VEP perimetry in recovered optic neuritis. In Perimetry update 2000", pp.2001, Kardon R
- Hood DC, "The multifocal visual evoked potential", J Neuroophthalmol, 23, pp.279~289 (2003)
- Klistorner A, "Objective perimetry in glaucoma", Ophthalmology, 107, pp.2283~2299 (2000)
- Odom JV, "ISCEV standard for clinical visual evoked potentials(2009 update)", Doc Ophthalmol, 120, pp.111~119 (2010)
- Halliday AM, "Delayed visual evoked response in optic neuritis", Lancet, 1, pp.982~985 (1972)
- Halliday AM, "Visual evoked response in diagnosis of multiple sclerosis", Br Med J, 4, pp.661~664 (1973)
- Halliday AM, "Changes in pattern-evoked responses in man associated with the vertical and horizontal meridians of the visual field", J Physiol, 208, pp.499~513 (1970)
- Michael WF, "Differences between the occipital distribution of upper and lower field pattern-evoked responses in man", Brain Res, 32, pp.311~324 (1971)
- Ossenblok P, "The extrastriate generators of the EP to checkerboard onset.A source localization approach", Electroencephalogr Clin Neurophysiol, 80, pp.181~193 (1991)
- Fortune B, "Conventional pattern-reversal VEPs are not equivalent to summed multifocal VEPs", Invest Ophthalmol Vis Sci, 44, pp.1364~1375 (2003)
- Howe JW, "Visual evoked cortical potential to paracentral retinal stimulation in chronic glaucoma,ocular hypertension,and an age-matched group of normals", Doc Ophthalmol, 63, pp.37~44 (1986)
- Hood DC, "Visual field defects and multifocal visual evoked potentials:evidence of a linear relationship", Arch Ophthalmol, 120, pp.1672~1681 (2002)
- Hood DC, "Quantifying the benefits of additional channels of multifocal VEP recording", Doc Ophthalmol, 104, pp.303~320 (2002)
- Slotnick SD, "Using multi-stimulus VEP source localization to obtain a retinotopic map of human primary visual cortex", Clin Neurophysiol, 110, pp.1793~1800 (1999)
- Hood DC, "Detecting glaucomatous damage with multifocal visual evoked potentials:how can a monocular test work?", J Glaucoma, 12, pp.3~15 (2003)
- Fortune B, "Normative ranges and specificity of the multifocal VEP", Doc Ophthalmol, 109, pp.87~100 (2004)
- Zhang X, "A principal component analysis of multifocal pattern reversal VEP", J Vis, 4, pp.32~43 (2004)
- Chen JY, "The effects of retinal abnormalities on the multifocal visual evoked potential", Invest Ophthalmol Vis Sci, 47, pp.4378~4385 (2006)
- Zhang X, "A signal-to-noise analysis of multifocal VEP responses:an objective definition for poor records", Doc Ophthalmol, 104, pp.287~302 (2002)
