본문 바로가기
KERD
논문KCI 등재

Evaluation of Anterior Segment Parameters in Obesity

2

조회

0

다운로드

1

인용

0

참고문헌

키워드

주제분류안과학

초록

Purpose: To investigate anterior segment parameters in obese patients in comparison to healthy individuals. Methods: Thirty-four obese subjects and 34 age-sex-matched healthy subjects were enrolled in this prospective cross-sectional study. Ophthalmological examinations including intraocular pressure (IOP), central corneal thickness (CCT), anterior chamber depth (ACD), anterior chamber volume (ACV), anterior chamber angle (ACA), and axial length (AL) measurements were performed on each subject. Height and weight of all subjects were recorded and body mass index (BMI) was calculated. Results: IOP was significantly higher in the obese group (p = 0.003). The mean ACD in obese subjects was significantly lower than that in control subjects (p = 0.036). AL, ACV, ACA and CCT were not significantly different between the groups. There was a positive correlation between BMI and IOP (r = 0.404, p < 0.001). ACD and ACA were negatively correlated with BMI. Conclusions: IOP was significantly higher and ACD was significantly lower in obese subjects. AL, ACV, ACA and CCT were not significantly different between the groups. The impact of obesity on anterior chamber parameters should be further investigated.

Abstract

Purpose: To investigate anterior segment parameters in obese patients in comparison to healthy individuals. Methods: Thirty-four obese subjects and 34 age-sex-matched healthy subjects were enrolled in this prospective cross-sectional study. Ophthalmological examinations including intraocular pressure (IOP), central corneal thickness (CCT), anterior chamber depth (ACD), anterior chamber volume (ACV), anterior chamber angle (ACA), and axial length (AL) measurements were performed on each subject. Height and weight of all subjects were recorded and body mass index (BMI) was calculated. Results: IOP was significantly higher in the obese group (p = 0.003). The mean ACD in obese subjects was significantly lower than that in control subjects (p = 0.036). AL, ACV, ACA and CCT were not significantly different between the groups. There was a positive correlation between BMI and IOP (r = 0.404, p < 0.001). ACD and ACA were negatively correlated with BMI. Conclusions: IOP was significantly higher and ACD was significantly lower in obese subjects. AL, ACV, ACA and CCT were not significantly different between the groups. The impact of obesity on anterior chamber parameters should be further investigated.

참고문헌 (35)

  1. World Health Organization, "Controlling the global obesity epidemic", pp.60~ (2002), World Health Organization
  2. Eckel RH, "American Heart Association call to action: obesity as a major risk factor for coronary heart disease", AHA Nutrition Committee. Circulation, 97, pp.2099~2100 (1998)
  3. Grundy SM, "Metabolic complications of obesity", Endocrine, 13, pp.155~165 (2000)
  4. Lawrence VJ, "Medical consequences of obesity", Clin Dermatol, 22, pp.296~302 (2004)
  5. Leske MC, "Diabetes, hypertension, and central obesity as cataract risk factors in a black population:the Barbados Eye Study", Ophthalmology, 106, pp.35~41 (1999)
  6. Kuang TM, "Body mass index and age-related cataract: the Shihpai Eye Study", Arch Ophthalmol, 123, pp.1109~1114 (2005)
  7. Leske MC, "Risk factors for open-angle glaucoma: the Barbados Eye Study", Arch Ophthalmol, 113, pp.918~924 (1995)
  8. Cheung N, "Obesity and eye diseases", Surv Ophthalmol, 52, pp.180~195 (2007)
  9. Van Leiden HA, "Blood pressure, lipids, and obesity are associated with retinopathy:the hoorn study", Diabetes Care, 25, pp.1320~1325 (2002)
  10. Seddon JM, "Progression of age-related macular degeneration: association with dietary fat, transunsaturated fat, nuts, and fish intake", Arch Ophthalmol, 121, pp.1728~1737 (2003)
  11. Maralani HG, "Metabolic syndrome and risk of age-related macular degeneration", Retina, 35, pp.459~466 (2015)
  12. Nemeth J, "Optical and ultrasound measurement of axial length and anterior chamber depth for intraocular lens power calculation", J Cataract Refract Surg, 29, pp.85~88 (2003)
  13. Abolbashari F, "Anterior segment characteristics of keratoconus eyes in a sample of Asian population", Cont Lens Anterior Eye, 36, pp.191~195 (2013)
  14. Lee Y, "Dynamic changes in anterior segment (AS) parameters in eyes with primary angle closure (PAC) and PAC glaucoma and open-angle eyes assessed using AS optical coherence tomography", Invest Ophthalmol Vis Sci, 53, pp.693~697 (2012)
  15. Malyugin BE, "Accommodative changes in anterior chamber depth in patients with high myopia", J Cataract Refract Surg, 38, pp.1403~1407 (2012)
  16. Tzamaloukas AH, "Classification of the degree of obesity by body mass index or by deviation from ideal weight", JPEN J Parenter Enteral Nutr, 27, pp.340~348 (2003)
  17. Wells JC, "Indices of whole-body and central adiposity for evaluating the metabolic load of obesity", Int J Obes (Lond), 29, pp.483~489 (2005)
  18. Gesta S, "Developmental origin of fat:tracking obesity to its source", Cell, 131, pp.242~256 (2007)
  19. Stojanov O, "The influence of retrobulbar adipose tissue volume upon intraocular pressure in obesity", Vojnosanit Pregl, 70, pp.469~476 (2013)
  20. Otto AJ, "Retrobulbar pressures measured during surgical decompression of the orbit", Br J Ophthalmol, 80, pp.1042~1045 (1996)
  21. Nassr MA, "Intraocular pressure change in orbital disease", Surv Ophthalmol, 54, pp.519~544 (2009)
  22. Mori K, "Relationship between intraocular pressure and obesity in Japan", Int J Epidemiol, 29, pp.661~666 (2000)
  23. Zafra Perez JJ, "Intraocular pressure and prevalence of occult glaucoma in a village of Murcia", Arch Soc Esp Oftalmol, 75, pp.171~178 (2000)
  24. Jang HD, "Relationship between intraocular pressure and parameters of obesity in Korean adults: the 2008-2010 Korea National Health and Nutrition Examination Survey", Curr Eye Res, (7) (2014)[DOI]
  25. Newman-Casey PA, "The relationship between components of metabolic syndrome and open-angle glaucoma", Ophthalmology, 118, pp.1318~1326 (2011)
  26. Lavanya R, "Determinants of angle closure in older Singaporeans", Arch Ophthalmol, 126, pp.686~691 (2008)
  27. Lowe RF, "Aetiology of the anatomical basis for primary angle-closure glaucoma. Biometrical comparisons between normal eyes and eyes with primary angle-closure glaucoma", Br J Ophthalmol, 54, pp.161~169 (1970)
  28. Halpern DL, "Glaucomatous optic neuropathy:mechanisms of disease", Ophthalmol Clin North Am, 15, pp.61~68 (2002)
  29. Saw SM, "Height and its relationship to refraction and biometry parameters in Singapore Chinese children", Invest Ophthalmol Vis Sci, 43, pp.1408~1413 (2002)
  30. Wong TY, "The relationship between ocular dimensions and refraction with adult stature:the Tanjong Pagar Survey", Invest Ophthalmol Vis Sci, 42, pp.1237~1242 (2001)
  31. Praveen MR, "Lens thickness of Indian eyes: impact of isolated lens opacity, age, axial length, and inf luence on anterior chamber depth", Eye (Lond), 23, pp.1542~1548 (2009)
  32. Sahinoglu-Keskek N, "Metabolic syndrome as a risk factor for elevated intraocular pressure", Pak J Med Sci, 30, pp.477~482 (2014)
  33. Su DH, "Central corneal thickness and its associations with ocular and systemic factors:the Singapore Malay Eye Study", Am J Ophthalmol, 147, pp.709~716 (2009)
  34. Nishitsuka K, "Determinants and risk factors for central corneal thickness in Japanese persons: the Funagata Study", Ophthalmic Epidemiol, 18, pp.244~249 (2011)
  35. Yin G, "Ocular axial length and its associations in Chinese: the Beijing Eye Study", PLoS One, 7, pp.43172~ (2012)

관련 논문AI추천

이 간행물의 다른 논문 (10건)