Short-term Analysis of the Residual Volume of an Eye Drop Following 23-Gauge Microincision Vitrectomy Surgery
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Purpose: To evaluate the change of residual volume of eye drop after instillation in patients with 23-gauge microincisionvitrectomy surgery (MIVS). Methods: Patient who were treated 23-gauge MIVS from November 2014 to July 2015 were included. The residualvolume was defined as the amount of remnant eye drop in patient’s eyes after instillation, calculated as thedifference between instillation volume and spilled volume of eye drop. Calculation of residual volume of eyedrop was performed one day before surgery, and daily from postoperative day 1 to day 5. Results: Forty consecutive patients were included. The residual volume of eye drop decreased from 30.3 ± 1.4μL at baseline to 13.0 ± 1.5 μL at day 1, 18.3 ± 1.6 μL at day 2, 24.7 ± 1.5 μL at day 3, and 27.9 ± 1.4 μL in day 4,postoperatively (p < 0.001, respectively). The volume at postoperative day 5 was 29.4 ± 1.3 μL, but it was notdifferent from the volume at baseline (p = 0.105). The change of residual volume was significantly correlatedwith postoperative chemosis (r = 0.672, p < 0.001) and effected by the number of quadrant with postoperativechemosis (p < 0.05). Conclusions: This study shows that postoperative residual volume of eye drop after instillation decreased untilpostoperative day 4, and postoperative chemosis affects the change of residual volume. Thus, checkingproper use of eye drops and teaching about instillation technique by physician is necessary for patients with23-gauge MIVS.
Abstract
Purpose: To evaluate the change of residual volume of eye drop after instillation in patients with 23-gauge microincisionvitrectomy surgery (MIVS). Methods: Patient who were treated 23-gauge MIVS from November 2014 to July 2015 were included. The residualvolume was defined as the amount of remnant eye drop in patient’s eyes after instillation, calculated as thedifference between instillation volume and spilled volume of eye drop. Calculation of residual volume of eyedrop was performed one day before surgery, and daily from postoperative day 1 to day 5. Results: Forty consecutive patients were included. The residual volume of eye drop decreased from 30.3 ± 1.4μL at baseline to 13.0 ± 1.5 μL at day 1, 18.3 ± 1.6 μL at day 2, 24.7 ± 1.5 μL at day 3, and 27.9 ± 1.4 μL in day 4,postoperatively (p < 0.001, respectively). The volume at postoperative day 5 was 29.4 ± 1.3 μL, but it was notdifferent from the volume at baseline (p = 0.105). The change of residual volume was significantly correlatedwith postoperative chemosis (r = 0.672, p < 0.001) and effected by the number of quadrant with postoperativechemosis (p < 0.05). Conclusions: This study shows that postoperative residual volume of eye drop after instillation decreased untilpostoperative day 4, and postoperative chemosis affects the change of residual volume. Thus, checkingproper use of eye drops and teaching about instillation technique by physician is necessary for patients with23-gauge MIVS.
참고문헌 (19)
- Gaudana R, "Ocular drug delivery", AAPS J, 12, pp.348~360 (2010)
- Olson RJ, "Reducing the risk of postoperative endophthalmitis", Surv Ophthalmol, (49 Suppl 2), pp.S55~S61 (2004)
- Androudi S, "Combined pars plana vitrectomy and phacoemulsification to restore visual acuity in patients with chronic uveitis", J Cataract Refract Surg, 31, pp.472~478 (2005)
- Winfield AJ, "A study of the causes of non-compliance by patients prescribed eyedrops", Br J Ophthalmol, 74, pp.477~480 (1990)
- Lund W, "The pharmaceutical codex: principles and practice of pharmaceutics", pp.14~ (1994), Pharmaceutical Press
- File RR, "Topically applied pilocarpine: human pupillary response as a function of drop size", Arch Ophthalmol, 98, pp.112~115 (1980)
- Gray RH, "The influence of drop size on pupil dilatation", Eye (Lond), 5(Pt 5), pp.615~619 (1991)
- Craig EW, "Effect on mydriasis of modifying the volume of phenylephrine drops", Br J Ophthalmol, 75, pp.222~223 (1991)
- Tatham AJ, "Eye drop instillation technique in patients with glaucoma", Eye (Lond), 27, pp.1293~1298 (2013)
- Costen MT, "Expanding role of local anaesthesia in vitreoretinal surgery", Eye (Lond), 19, pp.755~761 (2005)
- Barrio-Barrio J, "Graves' ophthalmopathy: VISA versus EUGOGO Classification, Assessment, and Management", J Ophthalmol, 2015, pp.249125~ (2015)
- Ritch R, "An improved technique of eye drop self-administration for patients with limited vision", Am J Ophthalmol, 135, pp.530~533 (2003)
- Brown MM, "Improper topical self-administration of ocular medication among patients with glaucoma", Can J Ophthalmol, 19, pp.2~5 (1984)
- Kholdebarin R, "Multicenter study of compliance and drop administration in glaucoma", Can J Ophthalmol, 43, pp.454~461 (2008)
- Lee SB, "The effect of mydriatics on posterior synechia after combined pars plana vitrectomy, phacoemulsification, and intraocular lens implantation", Retina, 29, pp.1150~1154 (2009)
- Mishima S, "Determination of tear volume and tear flow", Invest Ophthalmol, 5, pp.264~276 (1966)
- Allansmith MR, "Technical aspects of histamine determination in human tears", Am J Ophthalmol, 90, pp.719~724 (1980)
- Jones DT, "A novel method of tear collection: comparison of glass capillary micropipettes with porous polyester rods", Cornea, 16, pp.450~458 (1997)
- Choy CK, "Water-soluble antioxidants in human tears: effect of the collection method", Invest Ophthalmol Vis Sci, 42, pp.3130~3134 (2001)
