Ocular Dominance in Open-angle Glaucoma: The Shifting Trend Depending on Stage of the Disease
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Purpose: To investigate the characteristics and distribution of ocular dominance in primary open-angle glaucoma eyes. In addition,we tried to catch any trend of ocular dominance according to the stage of disease. Methods: Two hundred participants with bilateral open-angle glaucoma underwent ocular dominant testing by “the hole-ina-card” test. Using optical coherence tomography, macular ganglion cell-inner plexiform layer, as well as circumpapillary retinalnerve fiber layer thickness were measured and compared according to ocular dominance. Of the two eyes of one subject,the eye with less glaucomatous damage based on mean deviation was considered to be the “better eye” in our study. Results: Ocular dominance was in the right eye in 66% of the population and ocular dominance was positioned in the bettereye in 70% of the population (p = 0.001 and p = 0.002, respectively). In conditional logistic regression analyses, right eye andbetter mean deviation were significantly associated with ocular dominance (p = 0.001 and p = 0.002, respectively). Oculardominance tends to be present in the better eye and this trend was more apparent as the severity of glaucoma increased. Intereye comparison of visual field indices and retinal nerve fiber layer thickness between dominant versus nondominant eyebecome apparent in moderate and advanced glaucoma whereas it was not as apparent in early glaucoma. Conclusions: In glaucomatous eyes, laterality and severity of glaucoma determined ocular dominance. Intereye differencebetween nondominant and dominant eyes increased with the severity of glaucoma. Our findings suggest the existence of potentialreciprocal interactions between ocular dominance and glaucoma.
Abstract
Purpose: To investigate the characteristics and distribution of ocular dominance in primary open-angle glaucoma eyes. In addition,we tried to catch any trend of ocular dominance according to the stage of disease. Methods: Two hundred participants with bilateral open-angle glaucoma underwent ocular dominant testing by “the hole-ina-card” test. Using optical coherence tomography, macular ganglion cell-inner plexiform layer, as well as circumpapillary retinalnerve fiber layer thickness were measured and compared according to ocular dominance. Of the two eyes of one subject,the eye with less glaucomatous damage based on mean deviation was considered to be the “better eye” in our study. Results: Ocular dominance was in the right eye in 66% of the population and ocular dominance was positioned in the bettereye in 70% of the population (p = 0.001 and p = 0.002, respectively). In conditional logistic regression analyses, right eye andbetter mean deviation were significantly associated with ocular dominance (p = 0.001 and p = 0.002, respectively). Oculardominance tends to be present in the better eye and this trend was more apparent as the severity of glaucoma increased. Intereye comparison of visual field indices and retinal nerve fiber layer thickness between dominant versus nondominant eyebecome apparent in moderate and advanced glaucoma whereas it was not as apparent in early glaucoma. Conclusions: In glaucomatous eyes, laterality and severity of glaucoma determined ocular dominance. Intereye differencebetween nondominant and dominant eyes increased with the severity of glaucoma. Our findings suggest the existence of potentialreciprocal interactions between ocular dominance and glaucoma.
참고문헌 (26)
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