Membrane associated Ca2+ buffers in the heart
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Ca2+ is a universal signalling molecule that affects a variety of cellular processes including cardiac development. The majority of intracellular Ca2+ is stored in the endoplasmic and sarcoplasmic reticulum of muscle and non-muscle cells. Calreticulin is a well studied Ca2+-buffering protein in the endoplasmic reticulum, and calreticulin deficiency is embryonic lethal due to impaired cardiac development. Despite calsequestrin being the most abundant Ca2+-buffering protein in the sarcoplasmic reticulum, viability is maintained in embryos without calsequestrin and normal Ca2+ release and contractile function is observed. The Ca2+ homeostasis regulated by the endoplasmic and sarcoplasmic reticulum is critical for the development and proper function of the heart.
Abstract
Ca2+ is a universal signalling molecule that affects a variety of cellular processes including cardiac development. The majority of intracellular Ca2+ is stored in the endoplasmic and sarcoplasmic reticulum of muscle and non-muscle cells. Calreticulin is a well studied Ca2+-buffering protein in the endoplasmic reticulum, and calreticulin deficiency is embryonic lethal due to impaired cardiac development. Despite calsequestrin being the most abundant Ca2+-buffering protein in the sarcoplasmic reticulum, viability is maintained in embryos without calsequestrin and normal Ca2+ release and contractile function is observed. The Ca2+ homeostasis regulated by the endoplasmic and sarcoplasmic reticulum is critical for the development and proper function of the heart.
참고문헌 (75)
- Baumann, O., "Endoplasmic reticulum of animal cells and its organization into structural and functional domains", Int. Rev. Cytol., 205, pp.149~214 (2001)
- Berridge, M. J., "The versatility and universality of calcium signalling", Nat. Rev. Mol. Cell. Biol., 1, pp.11~21 (2000)
- Corbett, E. F., "Calcium, a signaling molecule in the endoplasmic reticulum?", Trends. Biochem. Sci., 25, pp.307~311 (2000)
- Nicchitta, C. V., "Biochemical, cell biological and immunological issues surrounding the endoplasmic reticulum chaperone GRP94", gp96, 1998, pp.10, 103~109
- Corbett, E. F., "Ca2+ regulation of interactions between endoplasmic reticulum chaperones", J. Biol. Chem., 274, pp.6203~6211 (1999)
- Molinari, M., "Chaperone selection during glycoprotein translocation into the endoplasmic reticulum", Science, 288, pp.331~333 (2000)
- Rossi, D., "The sarcoplasmic reticulum: an organized patchwork of specialized domains", Traffic, 9, pp.1044~1049 (2008)
- Rossi, A. E., "Sarcoplasmic reticulum: the dynamic calcium governor of muscle", Muscle Nerve, 33, pp.715~731 (2006)
- Vitadello, M., "Rabbit cardiac and skeletal myocytes differ in constitutive and inducible expression of the glucose-regulated protein GRP94", Biochem. J., 332, pp.351~359 (1998)
- Fliegel, L., "Molecular cloning of cDNA encoding a 55-kDa multifunctional thyroid hormone binding protein of skeletal muscle sarcoplasmic reticulum", J. Biol. Chem., 265, pp.15496~15502 (1990)
- Volpe, P., "The endoplasmic reticulum-sarcoplasmic reticulum connection: distribution of endoplasmic reticulum markers in the sarcoplasmic reticulum of skeletal muscle fibers", Proc. Natl. Acad. Sci. U.S.A., 통권 : 89, pp.6142~6146 (1992)
- Bootman, M. D., "Calcium signalling--an overview", Semin. Cell. Dev. Biol., 12, pp.3~10 (2001)
- Berridge, M. J., "Calcium signalling: dynamics, homeostasis and remodelling", Nat. Rev. Mol. Cell. Biol., 4, pp.517~529 (2003)
- Webb, S. E., "Calcium signalling during embryonic development", Nat. Rev. Mol. Cell. Biol., 4, pp.539~551 (2003)
- Baksh, S., "Interaction of calreticulin with protein disulfide isomerase", J. Biol. Chem., 270, pp.31338~31344 (1995)
- Putney, J. W., Jr., "Capacitative calcium entry channels", Bioessays, 21, pp.38~46 (1999)
- Kaufman, R. J., "Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls", Genes. Dev., 13, pp.1211~1233 (1999)
- Meldolesi, J., "The endoplasmic reticulum Ca2+ store: a view from the lumen", Trends. Biochem. Sci., 23, pp.10~14 (1998)
- Ashby, M. C., "ER calcium and the functions of intracellular organelles", Semin. Cell. Dev. Biol., 12, pp.11~17 (2001)
- Greber, U. F., "Depletion of calcium from the lumen of endoplasmic reticulum reversibly inhibits passive diffusion and signal-mediated transport into the nucleus", J. Cell. Bio.l, 128, pp.5~14 (1995)
- Stevens, F. J., "Protein folding in the ER", Semin. Cell. Dev. Biol., 10, pp.443~454 (1999)
- Liou, J., "STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx", Curr. Biol., 15, pp.1235~1241 (2005)
- Bastianutto, C., "Overexpression of calreticulin increases the Ca2+ capacity of rapidly exchanging Ca2+ stores and reveals aspects of their lumenal microenvironment and function", J. Cell. Biol., 130, pp.847~855 (1995)
- Mery, L., "Overexpression of calreticulin increases intracellular Ca2+ storage and decreases storeoperated Ca2+ influx", J. Biol. Chem., 271, pp.9332~9339 (1996)
- Arnaudeau, S., "Calreticulin differentially modulates calcium uptake and release in the endoplasmic reticulum and mitochondria", J. Biol. Chem., 277, pp.46696~46705 (2002)
- Baksh, S., "Expression of calreticulin in Escherichia coli and identification of its Ca2+ binding domains", J. Biol. Chem., 266, pp.21458~21465 (1991)
- Mesaeli, N., "Calreticulin is essential for cardiac development", J. Cell. Biol., 144, pp.857~868 (1999)
- Guo, L., "COUP-TF1 antagonizes Nkx2.5-mediated activation of the calreticulin gene during cardiac development", J. Biol. Chem., 276, pp.2797~2801 (2001)
- Koch, G., "Endoplasmic reticulum contains a common, abundant calcium-binding glycoprotein, endoplasmin", J. Cell. Sci., 86, pp.217~232 (1986)
- Haas, I. G., "Immunoglobulin heavy chain binding protein", Nature, 306, pp.387~389 (1983)
- Lievremont, J. P., "BiP, a major chaperone protein of the endoplasmic reticulum lumen, plays a direct and important role in the storage of the rapidly exchanging pool of Ca2+", J. Biol. Chem., 272, pp.30873~30879 (1997)
- Lebeche, D., "Calcium binding properties of rabbit liver protein disulfide isomerase", Biochem. Biophys. Res. Commun., 202, pp.556~561 (1994)
- Hirano, N., "Molecular cloning of the human glucose-regulated protein ERp57", GRP58, a thiol-dependent reductase. Identification of its secretory form and inducible expression by the oncogenic transformation, 1995, pp.234, 336~342
- Wada, I., "SSR alpha and associated calnexin are major calcium binding proteins of the endoplasmic reticulum membrane", J. Biol. Chem., 266, pp.19599~19610 (1991)
- Milner, R. E., "Calreticulin, and not calsequestrin, is the major calcium binding protein of smooth muscle sarcoplasmic reticulum and liver endoplasmic reticulum", J. Biol. Chem., 266, pp.7155~7165 (1991)
- MacLennan, D. H., "Ion tamers", Nat. Struct. Biol., 5, pp.409~411 (1998)
- MacLennan, D. H., "Ca2+ signalling and muscle disease", Eur. J. Biochem., 267, pp.5291~5297 (2000)
- Fan, G. C., "Regulatory roles of junctin in sarcoplasmic reticulum calcium cycling and myocardial function", Trends. Cardiovasc. Med., 18, pp.1~5 (2008)
- Kapoor, M., "Mutational analysis provides molecular insight into the carbohydrate-binding region of calreticulin: pivotal roles of tyrosine-109 and aspartate-135 in carbohydrate recognition", Biochemistry, 43, pp.97~106 (2004)
- Baksh, S., "Identification of the Zn2+ binding region in calreticulin", FEBS Lett., 376, pp.53~57 (1995)
- Andrin, C., "Expression and purification of mammalian calreticulin in Pichia pastoris", Protein. Expr. Purif., 20, pp.207~215 (2000)
- Oliver, J. D., "ERp57 functions as a subunit of specific complexes formed with the ER lectins calreticulin and calnexin", Mol. Biol. Cell., 10, pp.2573~2582 (1999)
- Ellgaard, L., "NMR structures of 36 and 73-residue fragments of the calreticulin P-domain", J. Mol. Biol., 322, pp.773~784 (2002)
- Frickel, E. M., "TROSY-NMR reveals interaction between ERp57 and the tip of the calreticulin P-domain", Proc. Natl. Acad. Sci. U.S.A., 통권 : 99, pp.1954~1959 (2002)
- Martin, V., "Identification by mutational analysis of amino acid residues essential in the chaperone function of calreticulin", J. Biol. Chem., 281, pp.2338~2346 (2006)
- Nakamura, K., "Functional specialization of calreticulin domains", J. Cell. Biol., 154, pp.961~972 (2001)
- Fasolato, C., "Delayed activation of the store-operated calcium current induced by calreticulin overexpression in RBL-1 cells", Mol. Biol. Cell., 9, pp.1513~1522 (1998)
- Camacho, P., "Calreticulin inhibits repetitive intracellular Ca2+ waves", Cell, 82, pp.765~771 (1995)
- John, L. M., "Differential modulation of SERCA2 isoforms by calreticulin", J. Cell. Biol., 142, pp.963~973 (1998)
- Coppolino, M. G., "Calreticulin is essential for integrin-mediated calcium signalling and cell adhesion", Nature, 386, pp.843~847 (1997)
- Hebert, D. N., "In and out of the ER: protein folding, quality control, degradation, and related human diseases", Physiol. Rev., 87, pp.1377~1408 (2007)
- Molinari, M., "Contrasting functions of calreticulin and calnexin in glycoprotein folding and ER quality control", Mol. Cell, 13, pp.125~135 (2004)
- Michalak, M., "Calreticulin, a multi-process calcium-buffering chaperone of the endoplasmic reticulum", Biochem. J., 417, pp.651~666 (2009)
- Treves, S., "Molecular cloning, functional expression and tissue distribution of the cDNA encoding frog skeletal muscle calsequestrin", Biochem. J., 283, pp.767~772 (1992)
- Slupsky, J. R., "Characterization of cardiac calsequestrin", Biochemistry, 26, pp.6539~6544 (1987)
- Yang, A., "A beneficial role of cardiac P2X4 receptors in heart failure: rescue of the calsequestrin overexpression model of cardiomyopathy", Am. J. Physiol. Heart. Circ. Physiol., 287, pp.H1096~H1103 (2004)
- Scott, B. T., "Complete amino acid sequence of canine cardiac calsequestrin deduced by cDNA cloning", J. Biol. Chem., 263, pp.8958~8964 (1988)
- Szegedi, C., "Calsequestrin: more than 'only' a luminal Ca2+ buffer inside the sarcoplasmic reticulum", Biochem. J., 337, pp.19~22 (1999)
- Gyorke, I., "The role of calsequestrin, triadin, and junctin in conferring cardiac ryanodine receptor responsiveness to luminal calcium", Biophys. J., 86, pp.2121~2128 (2004)
- Wanderling, S., "GRP94 is essential for mesoderm induction and muscle development because it regulates insulin-like growth factor secretion", Mol. Biol. Cell., 18, pp.3764~3775 (2007)
- Lozyk, M. D., "Ultrastructural analysis of development of myocardium in calreticulin-deficient mice", BMC. Dev. Biol., 6, pp.54~ (2006)
- Goncharova, E. J., "The involvement of adherens junction components in myofibrillogenesis in cultured cardiac myocytes", Development, 114, pp.173~183 (1992)
- Linask, K. K., "N-cadherin", catenin-mediated morphoregulation of somite formation, 1998, pp.202, 85~102
- Fadel, M. P., "Calreticulin affects beta-catenin- associated pathways", J. Biol. Chem., 276, pp.27083~27089 (2001)
- Fadel, M. P., "Calreticulin affects focal contact-dependent but not close contact-dependent cell-substratum adhesion", J. Biol. Chem., 274, pp.15085~15094 (1999)
- Nakamura, K., "Complete heart block and sudden death in mice overexpressing calreticulin", J. Clin. Invest., 107, pp.1245~1253 (2001)
- Knollmann, B. C., "Casq2 deletion causes sarcoplasmic reticulum volume increase, premature Ca2+ release, and catecholaminergic polymorphic ventricular tachycardia", J. Clin. Invest., 116, pp.2510~2520 (2006)
- Postma, A. V., "Absence of calsequestrin 2 causes severe forms of catecholaminergic polymorphic ventricular tachycardia", Circ Res., 91, pp.e21~e26 (2002)
- Sato, Y., "Cardiac-specific overexpression of mouse cardiac calsequestrin is associated with depressed cardiovascular function and hypertrophy in transgenic mice", J. Biol. Chem., 273, pp.28470~28477 (1998)
- Jones, L. R., "Regulation of Ca2+ signaling in transgenic mouse cardiac myocytes overexpressing calsequestrin", J. Clin. Invest., 101, pp.1385~1393 (1998)
- Miller, S. L., "Effects of calsequestrin over-expression on excitation- contraction coupling in isolated rabbit cardiomyocytes", Cardiovasc Res., 67, pp.667~677 (2005)
- Tsutsui, H., "Alterations in sarcoplasmic reticulum calcium- storing proteins in pressure-overload cardiac hypertrophy", Am. J. Physiol., 272, pp.H168~H175 (1997)
- Allen, B. G., "Calreticulin and calsequestrin are differentially distributed in canine heart", J. Mol. Cell. Cardiol., 32, pp.2379~2384 (2000)
- Kaakinen, M., "Microdomains of endoplasmic reticulum within the sarcoplasmic reticulum of skeletal myofibers", Exp. Cell. Res., 314, pp.237~245 (2008)
- Kaisto, T., "Distribution of the endoplasmic reticulum and its relationship with the sarcoplasmic reticulum in skeletal myofibers", Exp. Cell. Res., 289, pp.47~57 (2003)
