Interrelationship of Runx2 and estrogen pathway in skeletal tissues

키워드

참고문헌 (58)

1. Khosla, S, "Building bone to reverse osteoporosis and repair fractures", J. Clin. Invest, 118, pp.421~428 (2008)
2. Stein, G. S, "Runx2 control of organization, assembly and activity of the regulatory machinery for skeletal gene expression", Oncogene, 23, pp.4315~4329 (2004)
3. Choi, J. Y, "Subnuclear targeting of Runx", Cbfa, Proc. Natl. Acad. Sci. U.S.A, pp.2001, 98[DOI]
4. Komori, T, "Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts", Cell, 89, pp.755~764 (1997)
5. Otto, F, "Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development", Cell, 89, pp.765~771 (1997)
6. Banerjee, C, "Runt homology domain proteins in osteoblast differentiation: AML3", CBFA1 is a major component of a bone-specific complex, 1997, pp.66, 1~8
7. Ducy, P, "Osf2", Cbfa1: a transcriptional activator of osteoblast differentiation, 1997, pp.89, 747~754
8. Javed, A, "runt homology domain transcription factors (Runx, Cbfa, and AML) mediate repression of the bone sialoprotein promoter: evidence for promoter context-dependent activity of Cbfa proteins", Mol. Cell. Biol, 21, pp.2891~2905 (2001)
9. Pratap, J, "The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion", Mol. Cell. Biol, 25, pp.8581~8591 (2005)
10. Zaidi, S. K, "A specific targeting signal directs Runx2", Cbfa1 to subnuclear domains and contributes to transactivation of the osteocalcin gene, 2001, pp.114, 3093~3102
11. Han, M. S, "The cleidocranial dysplasia-related R131G mutation in the Runt-related transcription factor RUNX2 disrupts binding to DNA but not CBF-beta", J. Cell. Biochem, 110, pp.97~103 (2010), WILEY-LISS
12. Kim, H. J, "Four novel RUNX2 mutations including a splice donor site result in the cleidocranial dysplasia phenotype", J. Cell. Physiol, 207, pp.114~122 (2006)
13. Mundlos, S, "Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia", Cell, 89, pp.773~779 (1997)
14. Pratap, J, "Runx2 transcriptional activation of Indian Hedgehog and a downstream bone metastatic pathway in breast cancer cells", Cancer Res, 68, pp.7795~7802 (2008)
15. Zheng, Q, "Type X collagen gene regulation by Runx2 contributes directly to its hypertrophic chondrocyte-specific expression in vivo", J. Cell Biol, 162, pp.833~842 (2003)
16. Maruyama, Z, "Runx2 determines bone maturity and turnover rate in postnatal bone development and is involved in bone loss in estrogen deficiency", Dev. Dyn, 236, pp.1876~1890 (2007)
17. Syed, F, "Mechanisms of sex steroid effects on bone", Biochem. Biophys. Res. Commun, 328, pp.688~696 (2005)
18. Carani, C, "Effect of testosterone and estradiol in a man with aromatase deficiency", N. Engl. J. Med, 337, pp.91~95 (1997)
19. Deladoey, J, "Aromatase deficiency caused by a novel P450arom gene mutation: impact of absent estrogen production on serum gonadotropin concentration in a boy", J. Clin. Endocrinol. Metab, 84, pp.4050~4054 (1999)
20. Morishima, A, "Aromatase deficiency in male and female siblings caused by a novel mutation and the physiological role of estrogens", J. Clin. Endocrinol. Metab, 80, pp.3689~3698 (1995)
21. Smith, E. P, "Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man", N. Engl. J. Med, 331, pp.1056~1061 (1994)
22. Nakamura, T, "Estrogen prevents bone loss via estrogen receptor alpha and induction of Fas ligand in osteoclasts", Cell, 130, pp.811~823 (2007)
23. Martin-Millan, M, "The estrogen receptor-alpha in osteoclasts mediates the protective effects of estrogens on cancellous but not cortical bone", Mol. Endocrinol, 24, pp.323~334 (2010)
24. Park, H, "Interaction of Fas ligand and Fas expressed on osteoclast precursors increases osteoclastogenesis", JOURNAL OF IMMUNOLOGY, 175, pp.7193~7201 (2005), AMER ASSOC IMMUNOLOGISTS
25. Krum, S. A, "Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival", EMBO J, 27, pp.535~545 (2008)
26. Zallone, A, "Direct and indirect estrogen actions on osteoblasts and osteoclasts", Ann. N. Y. Acad. Sci, 1068, pp.173~179 (2006)
27. Jones, M. E, "Of mice and men: the evolving phenotype of aromatase deficiency", Trends Endocrinol. Metab, 17, pp.55~64 (2006)
28. Bulun, S. E, "The human CYP19 (aromatase P450) gene: update on physiologic roles and genomic organization of promoters", J. Steroid Biochem. Mol. Biol, 86, pp.219~224 (2003)
29. Simpson, E. R, "Aromatase--a brief overview", Annu. Rev. Physiol, 64, pp.93~127 (2002)
30. Simpson, E. R, "Aromatase cytochrome P450, the enzyme responsible for estrogen biosynthesis", Endocr. Rev, 15, pp.342~355 (1994)
31. Hinshelwood, M. M, "A 278 bp region just upstream of the human CYP19 (aromatase) gene mediates ovary-specific expression in transgenic mice", Endocrinology, 141, pp.2050~2053 (2000)
32. Mahendroo, M. S, "Tissue-specific expression of human P-450 AROM. The promoter responsible for expression in adipose tissue is different from that utilized in placenta", J. Biol. Chem, 266, pp.11276~11281 (1991)
33. Mahendroo, M. S, "Tissue-specific and hormonally controlled alternative promoters regulate aromatase cytochrome P450 gene expression in human adipose tissue", J. Biol. Chem, 268, pp.19463~19470 (1993)
34. Zhao, Y, "Characterization of the sequences of the human CYP19 (aromatase) gene that mediate regulation by glucocorticoids in adipose stromal cells and fetal hepatocytes", Mol. Endocrinol, 9, pp.340~349 (1995)
35. Pezzi, V, "Profiling transcript levels for steroidogenic enzymes in fetal tissues", J. Steroid Biochem. Mol. Biol, 87, pp.181~189 (2003)
36. Nawata, H, "Aromatase in bone cell: association with osteoporosis in postmenopausal women", J. Steroid Biochem. Mol. Biol, 53, pp.165~174 (1995)
37. Oz, O. K, "Expression of aromatase in the human growth plate", J. Mol. Endocrinol, 27, pp.249~253 (2001)
38. Sasano, H, "Aromatase in human bone tissue", J. Bone Miner Res, 12, pp.1416~1423 (1997)
39. Shozu, M, "Aromatase expression of human osteoblast-like cells", Mol. Cell. Endocrinol, 139, pp.117~129 (1998)
40. Tanaka, S, "Aromatase activity in human osteoblast- like osteosarcoma cell", Calcif. Tissue Int, 52, pp.107~109 (1993)
41. Sjogren, K, "Elevated aromatase expression in osteoblasts leads to increased bone mass without systemic adverse effects", J. Bone Miner Res, 24, pp.1263~1270 (2009)
42. Lea, C. K, "Aromatase cytochrome P450 transcripts are detected in fractured human bone but not in normal skeletal tissue", Bone, 21, pp.433~440 (1997)
43. Shozu, M, "TGF-beta1 stimulates expression of the aromatase (CYP19) gene in human osteoblast-like cells and THP-1 cells", Mol. Cell. Endocrinol, 160, pp.123~133 (2000)
44. Watanabe, M, "Forskolin and dexamethasone synergistically induce aromatase (CYP19) expression in the human osteoblastic cell line SV-HFO", Eur. J. Endocrinol, 152, pp.619~624 (2005)
45. Watanabe, M, "Aromatase expression in the human fetal osteoblastic cell line SV-HFO", J. Mol. Endocrinol, 32, pp.533~545 (2004)
46. Morioka, M, "Effect of interleukin-1beta on aromatase activity and cell proliferation in human osteoblast- like cells (HOS)", Biochem. Biophys. Res. Commun, 268, pp.60~64 (2000)
47. Enjuanes, A, "Regulation of CYP19 gene expression in primary human osteoblasts: effects of vitamin D and other treatments", Eur. J. Endocrinol, 148, pp.519~526 (2003)
48. Tanaka, S, "1,25-Dihydroxyvitamin D3 enhances the enzymatic activity and expression of the messenger ribonucleic acid for aromatase cytochrome P450 synergistically with dexamethasone depending on the vitamin D receptor level in cultured human osteoblasts", Endocrinology, 137, pp.1860~1869 (1996)
49. Jeong, J. H, "The Gene for Aromatase, a Rate-Limiting Enzyme for Local Estrogen Biosynthesis, Is a Downstream Target Gene of Runx2 in Skeletal Tissues", MOLECULAR AND CELLULAR BIOLOGY, 30, pp.2365~2375 (2010), AMER SOC MICROBIOLOGY
50. Miyaura, C, "Sex- and age-related response to aromatase deficiency in bone", Biochem. Biophys. Res. Commun, 280, pp.1062~1068 (2001)
51. Oz, O. K, "Bone phenotype of the aromatase deficient mouse", J. Steroid Biochem. Mol. Biol, 79, pp.49~59 (2001)
52. Oz, O. K, "Bone has a sexually dimorphic response to aromatase deficiency", J. Bone Miner Res, 15, pp.507~514 (2000)
53. Phillips, J. E, "Glucocorticoid-induced osteogenesis is negatively regulated by Runx2", Cbfa1 serine phosphorylation, 2006, pp.119, 581~591
54. Paredes, R, "Bone-specific transcription factor Runx2 interacts with the 1alpha,25-dihydroxyvitamin D3 receptor to up-regulate rat osteocalcin gene expression in osteoblastic cells", Mol. Cell. Biol, 24, pp.8847~8861 (2004)
55. Khalid, O, "Modulation of Runx2 activity by estrogen receptor-alpha: implications for osteoporosis and breast cancer", Endocrinology, 149, pp.5984~5995 (2008)
56. Teplyuk, N. M, "Runx2 regulates G protein- coupled signaling pathways to control growth of osteoblast progenitors", J. Biol. Chem, 283, pp.27585~27597 (2008)
57. Teplyuk, N. M, "The osteogenic transcription factor runx2 controls genes involved in sterol", steroid metabolism, including CYP11A1 in osteoblasts, 2009, pp.23, 849~861
58. Jeong, J. H, "Expression of Runx2 transcription factor in non-skeletal tissues, sperm and brain", JOURNAL OF CELLULAR PHYSIOLOGY, 217, pp.511~517, WILEY-LISS

관련 논문AI추천