Factors and Mechanisms Involved in the Coupling from Bone Resorption to Formation: How Osteoclasts Talk to Osteoblasts
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Bone remodeling is the fundamental means by which the quality as well as quantity ofthe skeleton is maintained throughout adult life. When bone remodeling goes awry, ametabolic bone disease such as osteoporosis ensues. Among multiple phases of thecomplex remodeling process, we focus in this review on factors and mechanisms thatare involved in the coupling of bone formation to preceding resorption.
Abstract
Bone remodeling is the fundamental means by which the quality as well as quantity ofthe skeleton is maintained throughout adult life. When bone remodeling goes awry, ametabolic bone disease such as osteoporosis ensues. Among multiple phases of thecomplex remodeling process, we focus in this review on factors and mechanisms thatare involved in the coupling of bone formation to preceding resorption.
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