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정상인과 정신지체인, 다운증후군 환자에서 치주질환 원인균의 출현율

Periodontopathic bacteria in subgingival plaque of normaland handicapped person

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정상인과 정신지체인 그리고 다운증후군 환자에서 치주상태 및 치주질환 원인균의 출현율을 비교 평가하고자 정상 학생 65명과 정신지체를 가진 학생 34명, 다운증후군을 가진 학생 28명, 총 127명을 조사대상으로 치태지수와 치은지수를 측정하고 치은연하 치태에 존재하는 Porphyromonas gingivalis, Tannerella forsythia(B. forsythus), Treponema denticola, Fusobacterium nucleatum, Actinobacillus actinomyce temcomitans 균을 중합효소연쇄반응을 이용하여 검사하고 다음과 같은 결과를 얻었다. 1. 치태지수와 치은지수는 정신지체인군과 다운증후군 환자군에서 정상인군보다 높았다. 2. 정신지체인군과 다운증후군 환자군은 정상인군에 비해 치주질환 원인균의 출현율이 높았으며 특히 P. gingivalis와 T. denticola, A. actinomycetemcomitans가 유의한 차이를 보였다. 다운증후군 환자군과 정신지체인군의 비교시 치주질환 원인균의 출현율은 유의한 차이를 보이지 않았다. 3. 연령별 비교시 정상인군의 P. gingivalis는 14세이상군에서 크게 증가하는 양상을 보였다. 정신지체인군과 다운증후군 환자군에서 P. gingivalis는 정상인군보다 조기에 더 높은 비율로 출현하였으며 연령의 증가에 따라 증가양상을 보였다. T. denticola, A. actinomycetemcomitans는 정상인군보다 정신지체인군과 다운증후군 환자군에서 모든 연령대에서 높은 비율을 보였다. 4. 치태지수는 T. denticola와 유의한 관련성이 있었으며, 치은지수는 T. denticola, A. actinomycetemcomitans와 높은 관련성을 보여주었다. 이상의 결과를 요약해 보면 정신지체인군과 다운증후군 환자군은 정상인군보다 치태지수, 치은지수가 더 높았으며, P. gingivalis, T. denticola, A. actinomycetemcomitans의 출현율에서 유의한 차이를 보였다. 다운증후군 환자군과 정신지체인군은 치주질환 원인균이 어린 시기부터 매우 높게 출현하였으며, 두 군간에는 유의할 만한 차이를 보이지 않았다.

Abstract

It is widely known that individuals with mental retardation (MR) and Down’s syndrome (DS) often develop early onset periodontal diseases. In this study, the prevalence of periodontopathic bacteria in MR persons and DS patients was compared with normal persons. Plaque index and gingival index were measured. Five periodontopathic bacteria, Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, Fusobacterium nucleatum were surveyed in subgingival plaque samples by the polymerase chain reaction. Results: 1. Plaque index and gingival index were higher in MR persons group and DS patients group than normal persons group(p<0.05). 2. The prevalence of periodontopathic bacteria in normal persons group were lower than that of MR persons group and DS. Significant differences were observed in the prevalence of P. gingivalis, T. denticola and A. actinomycetemcomitans(p<0.05). 3. Prevalence of P. gingivalis(5.9%) at age 8-10 was lower than other ages in normal persons group, and its prevalence increased with age. Prevalence of P. gingivalis, T. denticola and A. actinomycetemcomitans at MR persons group and DS patients group were higher than those of same ages of normal persons group. 4. Plaque index was associated with T. denticola and gingival index was associated with T. denticola and A. actinomycetemcomitans(p<0.05). These results suggested that plaque index, gingival index and prevalence of periodontopathic pathogens, especially P. gingivalis, T. denticola and A. actinomycetemcomitans in DS patients group and MR persons group are higher than those of normal persons group.

참고문헌 (48)

  1. "A longitudinal microbiological investigation of Actinobacillus actinomycetemcomitans and Eikenella corrodens in juvenile periodontitis", 45, pp.778~780 (1984)
  2. "Microbial etiological agents of destructive periodontal diseases", 5, pp.78~111 (1994)
  3. "Suspected periodontopathic microorganisms and their oral habitats in young children", 2, pp.60~64 (1987)
  4. "Microbiology of subgingival plaque from children with localized prepubertal periodontitis", 2, pp.71~76 (1987)
  5. "Detection of putative periodontal pathogens in subgingival specimens by 16S ribosomal DNA amplification with the polymerase chain reaction", 20(2), pp.304~307 (1995)
  6. "Reaction and dot-blot hybridization to monitor the distribution of oral pathogens within plaque samples of periodontally healthy individuals", 67, pp.994~1003 (1996)
  7. "Porphyromonas gingivalis,Actinobacillus actinomycetemcomitans and Treponema denticola detection in oral plaque samples using the polymerase chain reaction", 23, pp.212~219 (1996)
  8. "PCR detection of 5 putative periodontal pathogens in dental plaque samples from children 2 to 12 years of age", 28, pp.576~582 (2001)
  9. "Development of oral bacterial flora in young children", 32, pp.107~112 (2000)
  10. "Prevalence and microbiology of localized prepubertal periodontitis", 2, pp.65~70 (1987)
  11. "A retrospective radiographic study of alveolar bone loss in the primary dentition in patients with localized juvenile periodontitis", 16, pp.125~127 (1989)
  12. "Detection of Porphyromonas gingivalis in oral plaque samples by use of the polymerase chain reaction", 72, pp.1040~1044 (1993)
  13. "정신박약자의 구강위생상태 조사보고", 8, pp.477~480 (1970), 대한치과의사협회지
  14. "Streptococcus mutans counts,salivary pH,and periodontal treatment needs of adult Down syndrome patients", 11, pp.248~251 (1991)
  15. "Life expectancy in Down’s syndrome", 110, pp.849~854 (1987)
  16. "Periodontal disease associated with Down’s syndrome:an orthopantomographic evaluation", 48 (1977)
  17. "Periodontal disease in children with Down’s syndrome", pp.228~234 (1990)
  18. "Actinobacillus actinomycetemcomitans,Capnocytophaga and Porphyromonas gingivalis in subgingival plaque of adolescents with Down’s syndrome", 7, pp.244~248 (1992)
  19. "Periodontal disease in Down’s syndrome:a review", 13, pp.64~73 (1986)
  20. "Relationship of periodontopathic bacteria with earlyonset periodontitis in Down’s syndrome", 72, pp.368~373 (2001)
  21. "Morphological aspects of the gingiva in children with Down’s syndrome during experimental gingivitis", 15, pp.293~302 (1988)
  22. "Absence of a specific subgingival microflora in adults with Down’s syndrome", 28, pp.1004~1009 (2001)
  23. "Periodontopathic bacteria in children with Down’s syndrome", 71, pp.249~255 (2000)
  24. "Periodontal disease in pregnancy.Correlation between oral hygiene and periodontal condition", 22, pp.112~135 (1964)
  25. "The gingival index,the plaque index and the retention index system", 38, pp.610~616 (1927)
  26. "Polymerase chain reaction detection of 8 putative periodontal pathogens in subgingival plaque of gingivitis and advanced periodontitis lesions", 11, pp.266~273 (1996)
  27. "The predominant cultivable organisms in juvenile periodontitis", 84, pp.1~10 (1976)
  28. "The predominant cultivable microflora of advanced periodontitis", 85, pp.114~121 (1997)
  29. "Ultrastructure of the subgingival flora in juvenile periodontitis", 86, pp.421~429 (1978)
  30. "Structure of the microbial flora associated with periodontal health and disease in man:A light and electron microscopic study", 47, pp.1~18 (1976)
  31. "Microbial complexes in subgingival plaque", 25, pp.134~144 (1998)
  32. "Anonymous. Periodontal diseases: pathogenesis and microbial factors", 1, pp.926~932 (1996)
  33. "Actinobacillus actinomycetemcomitans in human periodontal disease:a cross-sectional microbiological investigation", 29, pp.1013~1020 (1980)
  34. "Studies of the microbiology of periodontosis", 47, pp.373~379 (1976)
  35. "Suppression of the periodontopathic microfiora in localized juvenile periodontitis by systemic tetracycline", 10, pp.465~486 (1983)
  36. "Clinical,microbiological and immunological features associated with the treatment of active periodontosis lesions", 11, pp.600~618 (1984)
  37. "Occurrence of Actinobacillus actimomycetemcomitans,Porphyromons gingivalis and Prevotella intermedia in progressive adult periodontitis", 71, pp.948~954 (2000)
  38. "Checkerboard”assessments of periodontal microbiota and their antibody responses:a case control study", 71, pp.885~987 (2000)
  39. "Bacteroides forsythus in adult gingivitis and periodontitis", 2, pp.152~157 (1987)
  40. "Electron microscopic observations of the bacterial flora of acute necrotizing ulcerative gingivitis", 36, pp.328~339 (1965)
  41. "Quantitative relationship of Treponema denticola to severity of periodontal disease", 56, pp.726~728 (1988)
  42. "Gramnegative species associated with active destructive periodontal lesions", 12, pp.648~659 (1985)
  43. "The prevalence of periodontitis and dental caries in a Down’s syndrome population", 57, pp.288~293 (1986)
  44. "Periodontopathic bacterial infection in childhood", 73, pp.20~26 (2002)
  45. "The distribution of periodontopathic bacteria among Japanese children and their parents", 39, pp.398~404 (2004)
  46. "어린이의 치은연하 치태내 치주질환 원인균의 출현율 조사" (2004), 경희대학교 대학원
  47. "Detection of Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis in dental plaque samples from children 2 to 12 years of age", 27, pp.763~768 (2000)
  48. "The relationship between gingivitis and colonization by Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans in children", 71, pp.403~409 (2000)

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