Analysis of Dental Antibiotic Prescriptions for Children and Adolescents in South Korea
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Antibiotics are used for the prevention and treatment of infections. This study aimed to investigate the patterns of dental antibiotic prescription in children and adolescents. The Health Insurance Review and Assessment Service provided data on patients who visited medical institutions. It was categorized according to year, sex, age, insurance type, dental institution, and region. Chi-square tests, Fisher’s exact tests, and one-way analyses of variance were performed. Statistical analyses were performed using SAS software (ver. 9.2; SAS Institute, Cary, NC, USA). Amoxicillin and cephalosporins, the most commonly used antibiotics, accounted for approximately 96% of the prescriptions. The younger the child, the more antibiotics were prescribed for trauma, pulpitis, and dental abscesses. However, closer to adolescence, the antibiotics were primarily prescribed to manage impacted teeth and periodontal problems. Antibiotics were prescribed for 3.13 days on average. There were significant differences in the prescription rates according to age, sex, type of insurance, type of medical institution, and region (p < 0.05). This study suggested that antibiotic prescriptions should be closely monitored to ensure appropriate usage of antibiotics.
Abstract
Antibiotics are used for the prevention and treatment of infections. This study aimed to investigate the patterns of dental antibiotic prescription in children and adolescents. The Health Insurance Review and Assessment Service provided data on patients who visited medical institutions. It was categorized according to year, sex, age, insurance type, dental institution, and region. Chi-square tests, Fisher’s exact tests, and one-way analyses of variance were performed. Statistical analyses were performed using SAS software (ver. 9.2; SAS Institute, Cary, NC, USA). Amoxicillin and cephalosporins, the most commonly used antibiotics, accounted for approximately 96% of the prescriptions. The younger the child, the more antibiotics were prescribed for trauma, pulpitis, and dental abscesses. However, closer to adolescence, the antibiotics were primarily prescribed to manage impacted teeth and periodontal problems. Antibiotics were prescribed for 3.13 days on average. There were significant differences in the prescription rates according to age, sex, type of insurance, type of medical institution, and region (p < 0.05). This study suggested that antibiotic prescriptions should be closely monitored to ensure appropriate usage of antibiotics.
참고문헌 (49)
- Ligon BL, "Penicillin : its discovery and early development", Semin Pediatr Infect Dis, 15, pp.52~57 (2004)
- 김혜성, "치과 환자의 항생제 처방에 영향을 주는 요인", 대한구강보건학회지, 41(1), pp.28~35 (2017), 대한예방치과·구강보건학회
- "How Antimicrobial Resistance Happens"[URL]
- Regea G, "Review on antibiotics resistance and its economic impacts", J Pharmacol Clin Res, 5, pp.555675~ (2018)
- WHO report on surveillance of antibiotic consumption: 2016-2018 early implementation, "World Health Organization", World Health Organization, ~ (2018)
- La Fauci V, "Antibiotic resistance : Where are we going?", Ann Ig, 30(4 Supple 1), pp.52~57 (2018)
- Yoon YK, "Trends of antibiotic consumption in Korea according to national reimbursement data(2008-2012) : a population-based epidemiologic study", Medicine, 94, pp.E2100~ (2015)
- "A master plan to combat antimicrobial resistance"[URL]
- 김백남, "Antibiotic Control Policies in South Korea, 2000-2013", Infection and Chemotherapy, 48(3), pp.151~159 (2016), 대한감염학회
- de Kraker ME, "Will 10million people die a year due to antimicrobial resistance by 2050?", PLoS Med, 13, pp.E1002184~ (2016)
- "Antibiotic Resistance Threats in the United States" (2019)[URL]
- "OECD stat, Pharmaceutical consumption-Antibacterials for systemic use"[URL]
- 최영준, "Trends in the use of antibiotics among Korean children", Clinical and Experimental Pediatrics, 62(4), pp.113~118 (2019), 대한소아청소년과학회
- Youngster I, "Antibiotic use in children - a cross-national analysis of 6 countries", J Pediatr, 182, pp.239~244 (2017)
- Marra F, "Antibiotic prescribing by dentists has increased : Why?", J Am Dent Assoc, 147, pp.320~327 (2016)
- Pipalova R, "The trends in antibiotic use by general dental practitioners in the Czech Republic(2006-2012)", Int Dent J, 64, pp.138~143 (2014)
- Yoon Young Choi, "Prescription of antibiotics after tooth extraction in adults: a nationwide study in Korea", 대한구강악안면외과학회지, 46(1), pp.49~57 (2020), 대한구강악안면외과학회[DOI]
- 이경희, "치과 외래 치료에서 항생제 처방에 영향을 주는 요인 - 한국 국민건강보험 표본코호트 연구 -", 한국치위생학회지, 19(3), pp.409~419 (2019), 한국치위생학회[DOI]
- 이한길, "빅데이터를 이용한 치면열구전색 급여화 이후의 소아청소년 치면열구전색 환자에 대한 분석", 대한소아치과학회지, 48(2), pp.129~139 (2021), 대한소아치과학회
- Kim LY, "Introduction of HIRA-NPS", HIRA Policy Trends, 6, pp.37~47 (2012)
- "Statistical Database, population"[URL]
- Durkin MJ, "An evaluation of dental antibiotic prescribing practices in the United States", J Am Dent Assoc, 148, pp.878~886 (2017)
- Sivaraman SS, "A national survey of pediatric dentists on antibiotic use in children", Pediatr Dent, 35, pp.546~549 (2013)
- Palmer NA, "A study of therapeutic antibiotic prescribing in National Health Service general dental practice in England", Br Dent J, 188, pp.554~558 (2000)
- Goel D, "Antibiotic prescriptions in pediatric dentistry : A review", J Fam Med Prim Care, 9, pp.473~480 (2020)
- Hills-Smith H, "Antibiotic therapy in pediatric dentistry. II. Treatment of oral infection and management of systemic disease", Pediatr Dent, 5, pp.45~50 (1983)
- Jayakaran TG, "Antibiotics and its use in pediatric dentistry : A review", Int J Appl Dent Sci, 4, pp.310~314 (2018)
- Aidasani B, "Antibiotics:their use and misuse in paediatric dentistry. A systematic review", Eur J Paediatr Dent, 20, pp.133~138 (2019)
- Rubanenko M, "Assessment of the Knowledge and Approach of General Dentists Who Treat Children and Pediatric Dentists Regarding the Proper Use of Antibiotics for Children", Antibiotics, 10, pp.1181~ (2021)
- American Academy of Pediatric Dentistry, "Use of antibiotic therapy for pediatric dental patients. The Reference Manual of Pediatric Dentistry", Am Acad Pediatr Dent, pp.495~499 (2022)
- Inchara R, "Preference of antibiotics in pediatric dentistry", Drug Invent Today, 11, pp.1495~1498 (2019)
- Thompson W, "Tackling antibiotic resistance : why dentistry matters", Int Dent J, 71, pp.450~453 (2021)
- Luo H, "Trends in use of dental care provider types and services in the United States in 2000-2016 : rural-urban comparisons", J Am Dent Assoc, 151, pp.596~606 (2020)
- Martin AB, "Rural-urban differences in dental service utilization among an early childhood population enrolled in South Carolina Medicaid", Matern Child Health J, 16, pp.203~211 (2012)
- Shlomo V, "The knowledge and expectations of parents about the role of antibiotic treatment in upper respiratory tract infection-a survey among parents attending the primary physician with their sick child", BMC Fam Prac, 4, pp.20~ (2003)
- 신선미, "Prevalence of Antibiotic Use for Pediatric Acute Upper Respiratory Tract Infections in Korea", Journal of Korean Medical Science, 30(5), pp.617~624 (2015), 대한의학회
- 임경욱, "진단 기준에 따른 취학전 어린이의 중증 유아기 우식증 유병률 비교", 대한소아치과학회지, 35(4), pp.677~683 (2008), 대한소아치과학회
- "Korean Children’s Oral Health Survey"[URL]
- 최은정, "소아치과 개원의 진료 현황 분석", 대한소아치과학회지, 33(3), pp.504~509 (2006), 대한소아치과학회
- 공미진, "1차 의료기관의 급성 상기도 감염 질환자 의약품 처방특성 - 가정의학과, 내과, 소아청소년과, 이비인후과, 일반의 중심으로 -", 보건의료산업학회지, 11(3), pp.37~49 (2017), 보건의료산업학회
- "Use of Antibiotic Therapy for Paediatric Dentistry:Foundational Articles and Consensus Recommendations" (2021)[URL]
- Ahmadi H, "Antibiotic therapy in dentistry", Int J Dent, 2021, pp.6667624~ (2021)
- Andersson L, "International Association of Dental Traumatology guidelines for the management of traumatic dental injuries: 2. Avulsion of permanent teeth", Dent Traumatol, 28, pp.88~96 (2012)
- "Amoxicillin"[URL]
- Wilson WR, "Prevention of viridans group streptococcal infective endocarditis : a scientific statement from the American Heart Association", Circulation, 143, pp.E963~E978 (2021)
- Andreasen JO, "The role of antibiotics in preventing healing complications after traumatic dental injuries : a literature review", Endod Topics, 14, pp.80~92 (2006)
- Lam R, "Dental trauma in an Australian rural centre", Dent Traumatol, 24, pp.663~670 (2008)
- Kassebaum NJ, "Global burden of severe periodontitis in 1990-2010 : a systematic review and meta-regression", J Dent Res, 93, pp.1045~1053 (2014)
- Chassin MR, "The urgent need to improve health care quality. Institute of Medicine National Roundtable on Health Care Quality", JAMA, 280, pp.1000~1005 (1998)
