치과 외래 치료에서 항생제 처방에 영향을 주는 요인 - 한국 국민건강보험 표본코호트 연구 -
Factors affecting antibiotic prescription in dental outpatients - A nation-wide cohort study in Korea -
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Objectives: The purpose of this study was to analyze the factors affecting antibiotic prescription in dental outpatients. Methods: The present study was conducted using data from the National Health Insurance Service – National Sample Cohort. We analyzed prescriptions issued in the dental outpatient department in 2015, for adults over 19 years of age. Antibiotic prescription rates and mean prescription days were analyzed by sex, age, insurance type, presence of diabetes mellitus and hypertension, season in treatment, type of dental institution, and location of dental institution. Multivariate logistic regression was also performed to analyze the factors affecting antibiotic prescription in dental outpatients. Results: A total of 257,038 prescriptions were analyzed. The mean prescription days of antibiotics in dental outpatients were 3.04±1.08 days, and the prescription rate was 93.0%. Two variables (presence of diabetes mellitus and insurance type) were excluded from the multivariate logistic regression analysis model because they did not significantly affect antibiotic prescription. The possibility of antibiotic prescription was higher in men ≥61 years of age and those with hypertension. Furthermore, antibiotics were most frequently prescribed in dental clinics rather than dental hospitals, and more frequently in Busan compared to other areas ( p <0.001). Conclusions: Several factors were determined to affect antibiotic prescription, and detailed guidelines for consistent antibiotic prescription are needed.
Abstract
Objectives: The purpose of this study was to analyze the factors affecting antibiotic prescription in dental outpatients. Methods: The present study was conducted using data from the National Health Insurance Service – National Sample Cohort. We analyzed prescriptions issued in the dental outpatient department in 2015, for adults over 19 years of age. Antibiotic prescription rates and mean prescription days were analyzed by sex, age, insurance type, presence of diabetes mellitus and hypertension, season in treatment, type of dental institution, and location of dental institution. Multivariate logistic regression was also performed to analyze the factors affecting antibiotic prescription in dental outpatients. Results: A total of 257,038 prescriptions were analyzed. The mean prescription days of antibiotics in dental outpatients were 3.04±1.08 days, and the prescription rate was 93.0%. Two variables (presence of diabetes mellitus and insurance type) were excluded from the multivariate logistic regression analysis model because they did not significantly affect antibiotic prescription. The possibility of antibiotic prescription was higher in men ≥61 years of age and those with hypertension. Furthermore, antibiotics were most frequently prescribed in dental clinics rather than dental hospitals, and more frequently in Busan compared to other areas ( p <0.001). Conclusions: Several factors were determined to affect antibiotic prescription, and detailed guidelines for consistent antibiotic prescription are needed.
참고문헌 (25)
- Najla S. Dar-Odeh, "Analysis of clinical records of dental patients attending Jordan University Hospital: Documentation of drug prescriptions and local anesthetic injections", Therapeutics and Clinical Risk Management, 44(5), pp.1111~1117 (2008), Informa UK Limited[DOI]
- N. Palmer, "A study of therapeutic antibiotic prescribing in National Health Service general dental practice in England", British Dental Journal, 188(10), pp.554~558 (2000), Springer Science and Business Media LLC[DOI]
- Yingling NM, "Antibiotic use by members of the American Association of Endodontists in the year 2000 : report of a national survey", J Endod, 28(5), pp.396~404 (2002)[DOI]
- "Antimicrobial resistance: global report on surveillance" (2014)[URL]
- 최정현, "적절한 항생제 사용의 의미와 영향", Infection and Chemotherapy, 44(5), pp.331~337 (2012), 대한감염학회[DOI]
- 이정림, "한국인의 구강에서 분리된 Staphylococcus aureus의 항생제 내성양상", 대한구강악안면병리학회지, 35(1), pp.31~36 (2011), 대한구강악안면병리학회
- 조한아, "처방전 발행률로 본 치과의료기관 의약품 사용실태", 대한구강보건학회지, 38(4), pp.212~219 (2014), 대한예방치과·구강보건학회
- Michael J. Durkin, "An evaluation of dental antibiotic prescribing practices in the United States", The Journal of the American Dental Association, 148(12), pp.878~886.e1 (2017), Elsevier BV[DOI]
- Al-Haroni M, "Incidence of antibiotic prescribing in dental practice in Norway and its contribution to national consumption", J Antimicrob Chemother, 59(6), pp.1161~1166 (2007)[DOI]
- Rachel Pipalova, "The trends in antibiotic use by general dental practitioners in the Czech Republic (2006-2012)", International Dental Journal, 64(3), pp.138~143 (2014), Wiley[DOI]
- Marra F, "Antibiotic prescribing by dentists has increased : Why", J Am Dent Assoc, 147(5), pp.320~327 (2016)[DOI]
- Frank Halling, "Trends in antibiotic prescribing by dental practitioners in Germany", Journal of Cranio-Maxillofacial Surgery, 45(11), pp.1854~1859 (2017), Elsevier BV[DOI]
- Sukhvinder S. Oberoi, "Antibiotics in dental practice: how justified are we", International Dental Journal, 65(1), pp.4~10 (2015), Wiley[DOI]
- Anwen L. Cope, "Antibiotic prescribing in UK general dental practice: a cross-sectional study", Community Dentistry and Oral Epidemiology, 44(2), pp.145~153 (2016), Wiley[DOI]
- 김혜성, "치과 환자의 항생제 처방에 영향을 주는 요인", 대한구강보건학회지, 41(1), pp.28~35 (2017), 대한예방치과·구강보건학회
- Lee J, "Cohort profile : The national health insurance service–national sample cohort(NHIS-NSC), South Korea", Int J Epidemiol, 46(2), pp.e15~ (2017)[DOI]
- 최원정, "급성상기도감염 환자의 항생제 처방에 영향을 주는 요인", 보건행정학회지, 25(4), pp.256~263 (2015), 한국보건행정학회
- Gong MJ, "Clinical department prescription drugs characteristics of Acute upper respiratory tract infection disease", Master, pp.2016
- Shukan Kanuga, "Short-term oral antibiotics may be as effective as the standard course of penicillin for children with acute streptococcal pharyngitis", The Journal of the American Dental Association, 146(12), pp.927~928 (2015), Elsevier BV[DOI]
- Rachida el Moussaoui, "Effectiveness of discontinuing antibiotic treatment after three days versus eight days in mild to moderate-severe community acquired pneumonia: randomised, double blind study", BMJ, 332(7554), pp.1355~ (2006), BMJ[DOI]
- David Colquhoun, "An investigation of the false discovery rate and the misinterpretation of p -values", Royal Society Open Science, 1(3), pp.140216~ (2014), The Royal Society[DOI]
- Hong-Jun Cho, "Knowledge and beliefs of primary care physicians, pharmacists, and parents on antibiotic use for the pediatric common cold", Social Science & Medicine, 58(3), pp.623~629 (2004), Elsevier BV[DOI]
- 김남순, "급성 상기도 질환에서 일차의료의사의 항생제 처방에 영향을 주는 요인", 예방의학회지, 38(1), pp.1~8 (2005), 대한예방의학회
- 조세형, "치과분야 항생제 처방에 대한 국내외 문헌 분석", 대한구강악안면외과학회지, 35(3), pp.164~169 (2009), 대한구강악안면외과학회
- DARRYL C. TONG, "ANTIBIOTIC PROPHYLAXIS IN DENTISTRY: A REVIEW AND PRACTICE RECOMMENDATIONS", The Journal of the American Dental Association, 131(3), pp.366~374 (2000), Elsevier BV[DOI]