폐암 환자의 정위체부방사선치료 시 호흡인자를 적용한 방사선 치료계획의 유용성
Usefulness of Radiation Treatment Planning Applied Respiration Factor for Stereotactic Body Radiation Therapy in the Lung Cancer
1
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
본 연구는 폐암 환자의 정위방사선치료 시 환자의 호흡인자를 적용한 치료계획을 설정하여 그 유용성을 평가하고자 하였다. 폐암 환자 10명을 대상으로 4차원 컴퓨터단층촬영을 시행하고, 환자의 호흡 인자를 적용한 치료계획과 기존의 치료계획과 비교 평가하였다. 실험은 폐의 용적변화, 폐의 방사선 흡수선량 변화, 폐암 주위의 중요 장기의 흡수선량 등을 분석하였다. 본 연구에서 호흡인자를 적용한 방사선 치료계획 시 기존의 방법과 비교하여 폐의 용적변화, 폐의 방사선 흡수선량 변화, 폐암 주위의 중요 장기의 흡수선량의 차이를 확인할 수 있었다. 결론적으로 폐암 환자의 정위체부방사선치료를 위하여 호흡인자를 적용한 방사선 치료계획 방법은 유용할 것으로 사료된다.
Abstract
We are evaluated the usefulness of radiation treatment planning applied respiration factor for stereotactic body radiation therapy in the lung cancer. Four dimensional computed tomography images were obtained in 10 patients with lung cancer. The radiation treatment plans were established total lung volume according to respiration images (new method) and conventional method. We was analyzed in the lung volume, radiation absorbed dose of lung and main organs (ribs, tracheobronchus, esophagus, spinal cord) around the tumor, respectively. We were confirmed that lung volume and radiation absorbed dose of lung and main organs around the tumor deference according to applied respiration. In conclusion, radiation treatment planning applied respiration factor seems to be useful for stereotactic body radiation therapy in thelung cancer.
참고문헌 (12)
- Robert Timmerman, "Stereotactic Body Radiation Therapy for Inoperable Early Stage Lung Cancer", American Medical Association, pp.1070~1076 (2010)
- Hiroshi Onishi, "Stereotactic Body Radiotherapy (SBRT) For operable Stage I Non-Small Cell Lung Cancer: Can SBRT be comparable to surgery?", International Journal Of Radiation Oncology Biology Physics, 81(5), pp.1352~1358 (2011)
- Tracey, "A Phase I", Ⅱ Trial of Stereotactic Body Radiation Therapy (SBRT) for Lung Metastases: Initial report of Dose Escalation and Early Toxicity, 2006, S120~S127
- Matthias Guckenbergera, "Pulmonary Injury and Tumor Response after Stereotactic Body Radiotherapy (SBRT): Results of a Serial Follow-up CT Study", Radiotherapy and Oncology, 85, pp.435~442 (2007)
- Jianzhou Wu, "An Evaluation of Planning Techniques for Stereotactic Body Radiation Therapy in Lung Tumor", Radiotherapy and Oncology, 87, pp.35~43 (2008)
- Yvette Seppenwoolde, "Comparing Different NTCP Models that Predict the Incidence of Radiation Pneumonitis", International Journal Of Radiation Oncology Biology Physics, 55(3), pp.724~735 (2003)
- S. Senan, "Stereotactic Radiotherapy For Stage Ⅰ Lung Cancer: Current Results And New Developments", Cancer Radiotherapy, 14, pp.115~118 (2010)
- Alice W.Y Ng, "Hypofractionated Stereotactic Radiotherapy for Medically Inoperable Stage, Non-Small Cell Lung Cancer – Report on Clinical Outcome and Dose to Critical Organs", Radiotherapy and Oncology, 87, pp.24~28 (2008)
- Trovo, "Early and Late Lung Radiographic Injury Following Stereotactic Body Radiation Therapy", Lung Cancer, 69, pp.77~85 (2010)
- Guckenberger, "Pulmonary Injury and tumor response after Stereotactic Body Radiation Therapy (SBRT) : Result of a Serial Follow-up CT Study", Radiotherapy and Oncology, 85, pp.435~442 (2007)
- Stanley. Benedict, "Stereotactic Body Radiation Therapy: The Report of AAPM Task Group 101", Medical Physics, 37(8) (2010)
- Neal, Dunlap, "Chest Wall Volume Receiving >30gy Predicts Risk of Severe Pain And", or Rib Fracture After Lung Stereo Static Body Radiotherapy, 2010, pp.76(3), 796~801