마이크로 4.7T MRI SE Sequence에서 T2강조효과를 위한 최적의 Flip Angle
Optimal Flip A ngle f or T 2-Weighted E ffect i n Micro 4.7T MRI S E S equence
1
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
The purpose of this study was to investigate the FA value which can produce the best T2-weighted images by measuring the signal intensity and noise according to the FA value change in the brain image and the abdominal image of the mouse using micro–MRI. Brain imaging and abdominal imaging of BALB / C mice weighing 20g were performed using 4.7T (Bruker BioSpin MRI GmbH) micro-MRI equipment, Turbo RARE-T2 (spin echo-T2) images were scanned at TR 3500 msec and TE 36 msec. The changes of the FA values were 60°, 80°, 100°, 120°, 140°, 160° and 180°. We measured signal intensity according to FA values of ventricle and thalamus in brain imaging, The signal intensity of kidney and muscle around the kidney was measured in abdominal images. To obtain SNR and CNR, we measured the background signals of two different parts, not the tissue. In the brain (thalamus) image, the signal intensity of FA 100° was 7,433 and SNR (6.49) was the highest. In the abdominal (kidney) image, the signal intensity was highest at 16,523 when FA was 120°, and the highest SNR was 8.54 when FA was 140°. The CNR value of the brain image was 1.38 at FA 60° and gradually increased to 8.29 at FA 180°. The CNR value of the muscle adjacent to the kidney gradually increased from 2.36 when the FA value was 60° and the highest value was 4,57 at the FA value 180°.
Abstract
The purpose of this study was to investigate the FA value which can produce the best T2-weighted images by measuring the signal intensity and noise according to the FA value change in the brain image and the abdominal image of the mouse using micro–MRI. Brain imaging and abdominal imaging of BALB / C mice weighing 20g were performed using 4.7T (Bruker BioSpin MRI GmbH) micro-MRI equipment, Turbo RARE-T2 (spin echo-T2) images were scanned at TR 3500 msec and TE 36 msec. The changes of the FA values were 60°, 80°, 100°, 120°, 140°, 160° and 180°. We measured signal intensity according to FA values of ventricle and thalamus in brain imaging, The signal intensity of kidney and muscle around the kidney was measured in abdominal images. To obtain SNR and CNR, we measured the background signals of two different parts, not the tissue. In the brain (thalamus) image, the signal intensity of FA 100° was 7,433 and SNR (6.49) was the highest. In the abdominal (kidney) image, the signal intensity was highest at 16,523 when FA was 120°, and the highest SNR was 8.54 when FA was 140°. The CNR value of the brain image was 1.38 at FA 60° and gradually increased to 8.29 at FA 180°. The CNR value of the muscle adjacent to the kidney gradually increased from 2.36 when the FA value was 60° and the highest value was 4,57 at the FA value 180°.
참고문헌 (12)
- 고성진, "자기공명영상에서 자장세기와 시퀀스에 따른 아티팩트 변화", 한국콘텐츠학회 논문지, 10(9), pp.302~308 (2010), 한국콘텐츠학회
- Pomper, MG, "Molecular imaging: an overview", Acad. Radiology, 8(11), pp.1141~1153 (2001)
- Weissleder R, "Molecular imaging", Radiology, 219(2), pp.316~333 (2001)
- Massoud TF, "Molecular imaging in living subject : seeing fundamental biological processes in a new light", Genes & Development, 17(5), pp.545~580 (2003)
- Crooks LE, "Instrumentation and techniques-Magnetic resonance imageing of the body 2", pp.21~ (1987), Raven press
- Vogel-Claussen J, "Carcliac Valve Assessment with MR Irnaging and 64-Section Multi-Detector Row CT", RadioGraphics, 26(6), pp.1769~1784 (2006)
- 배성진, "3T MR 스핀에코 T1강조영상에서 적정의 숙임각", 방사선기술과학, 32(2), pp.177~182 (2009), 대한방사선과학회
- Mills TC, "Partial flip angle MR imaging", Radiology, 162, pp.531~539 (1987)
- Callaghan PT, "Principles of nuclear magnetic resonance microscopy" (1991), Clarendon Press
- 이상호, "최적의 FOV를 위한 MR신호강도와 신호 대 잡음비 값의 비교분석", 방사선기술과학, 41(2), pp.109~113 (2018), 대한방사선과학회[DOI]
- Hennig J, "Multiecho sequences with variable efocusing flip angles: optimization of signal behavior using smooth transitions between pseudo steady states(TRAPS)", Magn Reson Med, 49, pp.527~535 (2003)
- Weigel M, "Neuroradiological Applications of Hyperecho-TSE sequences at 3T:first clinical results", Proceedings of the 12th Annual Meeting of 19 ISMRM, pp.76~ (2004)