하치조 신경 손상 및 회복에 대한 고찰
Inferior alveolar nerve injury and recovery
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참고문헌
초록
Inferior a1veo1ar nerve (IAN) is the branch of mandibu1ar division of trigemina1 nerve and is one of the most important nerves in oromaxillary area. In many clinica1 situations. there is the possibi1ity of IAN being injured. Thus, the anatomic properties of IAN were studied first. We a1so studied the reasons of IAN l nJ Ury, the diagnostic methods which he1p determine the extent of injury and the methods for treatment of injured nerve. We reviewed the bio1ogica1 changes of injured IAN. IAN cou1d be damaged from 10wer third mo1ar extraction or imp1ant surgery. When IAN is injured, all the parts of IAN including cell body, axon , Schwann cell and nerve ending wou1d be changed for the nerve regeneration. Schwann cells seem to have a very important ro1e in this process. There are severa1 methods for eva1uating the extent of IAN injury: static 1ight touch test , dynamic 1ight touch test , two point discrimination test. therma1 sense test. e1ectrophysio1ogic test and digita1 infrared therma1 imaging. Injured IAN can be treated by pharmaco1ogica1 therapies. physica1 therapies. and surgica1 interventions such as anastomosis and nerve graft. Recently. the studies on new intervention of using nerve conduits or Schwann cells in IAN repair are on progress.
Abstract
Inferior a1veo1ar nerve (IAN) is the branch of mandibu1ar division of trigemina1 nerve and is one of the most important nerves in oromaxillary area. In many clinica1 situations. there is the possibi1ity of IAN being injured. Thus, the anatomic properties of IAN were studied first. We a1so studied the reasons of IAN l nJ Ury, the diagnostic methods which he1p determine the extent of injury and the methods for treatment of injured nerve. We reviewed the bio1ogica1 changes of injured IAN. IAN cou1d be damaged from 10wer third mo1ar extraction or imp1ant surgery. When IAN is injured, all the parts of IAN including cell body, axon , Schwann cell and nerve ending wou1d be changed for the nerve regeneration. Schwann cells seem to have a very important ro1e in this process. There are severa1 methods for eva1uating the extent of IAN injury: static 1ight touch test , dynamic 1ight touch test , two point discrimination test. therma1 sense test. e1ectrophysio1ogic test and digita1 infrared therma1 imaging. Injured IAN can be treated by pharmaco1ogica1 therapies. physica1 therapies. and surgica1 interventions such as anastomosis and nerve graft. Recently. the studies on new intervention of using nerve conduits or Schwann cells in IAN repair are on progress.
참고문헌 (138)
- Wadu SG, "Townsend GC: Morphological variability of the human inferior alveolar nerve", Clinical Anatomy, 10(2), pp.82~87 (1997)
- Dario LJ, "Implant placement above a bifurcated mandibular canal: A case report", Implant Dentistry, 11(3), pp.258~ (2002)
- Driscoll CF, "Bifid mandibular canal", Oral surgery, oral medicine, and oral pathology, 70(6), pp.807~ (1990)
- Agthong S, "Anatomical variations of the supraorbi tal. infraorbital. and mental foramina related to gender and side", Journal of oral and maxillofacial surgery, 63(6), pp.800~804 (2005)
- Neiva RF, "Morphometric analysis of implantrelated anatomy in Caucasian skulls", Journal of periodontology, 75(8), pp.1061~1067 (2004)
- Fishel D, "Roentgenologic study of the mental foramen", Oral Surgery, Oral Medicine, Oral Pathology, 41(5), pp.682~686 (1976)
- Ngeow WC, "The location of the mental foramen in a selected Malay population", Journal of oral science, 45(3), pp.171~176 (2003)
- Mraiwa N, "Presence and course of the inclslve canal in the human mandibular interforaminal region: two-dimensional imaging versus anatomical observations", Surgical and Radiologic Anatomy, 25(5), pp.416~423 (2003)
- Polland KE, "The mandibular canal of the edentulous jaw", Clinical Anatomy, 14(6), pp.445~452 (2001)
- Hillerup S, "Nerve inJury caused by mandibular block analgesia", International journal of oral and maxillofacial surgery, 35(5), pp.437~443 (2006)
- Grotz K, "Treatment of injuries to the inferior alveolar nerve after endodontic procedures", Clinical oral investigations, 2(2), pp.73~76 (1998)
- Kraut RA, "Management of patients with trigeminal nerve injuries after mandibular implant placement", The Journal of the American Dental Association, 133(10), pp.1351~ (2002)
- Wismeijer D, "Patients' perception of sensory disturbances of the mental nerve before and after implant surgery: a prospective study of 110 patients", British Journal of Oral and Maxillofacial Surgery, 35(4), pp.254~259 (1997)
- Bataineh AB, "Sensory nerve impairment following mandibular third molar surgery", Journal of oral and maxillofacial surgery, 59(9), pp.1012~1017 (2001)
- Carmichael F, "Incidence of nerve damage following third molar removal: a West of Scotland Oral Surgery Research Group study", British Journal of Oral and Maxillofacial Surgery, 30(2), pp.78~82 (1992)
- Loescher A, "Nerve damage and third molar removal", Dent Update, 30(7), pp.375~382 (2003)
- Hillerup S, "Iatrogenic injury to oral branches of the trigeminal nerve: records of 449 cases", Clinical oral investigations, 11(2), pp.133~142 (2007)
- 유지원, "치과의사에 의해 보고된 발치 및 임프란트 수술 후 지각이상에 대한 분석", Journal of Oral Medicine and Pain, 32(3), pp.263~272 (2007), 대한안면통증∙구강내과학회
- Mason D, "Lingual nerve damage following lower third molar surgery", International journal of oral and maxillofacial surgery, 17(5), pp.290~294 (1988)
- Pogrel MA, "Thamby S: PERMANENT NERVE INVOLVEMENT RESULTING: FROM INFERIOR ALVEOLAR NERVE BLOCKS", The Journal of the American Dental Association, 131(7), pp.901~ (2000)
- Harn S, "Incidence of lingual nerve trauma and postinjection complications in conventional mandibular block anesthesia", The Journal of the American Dental Association, 121(4), pp.519~ (1990)
- Krafft TC, "Clinical investigation into the incidence of direct damage to the lingual nerve caused by 10cal anaesthesia", Journal of Cranio-Maxillofacial Surgery, 22(5), pp.294~296 (1994)
- Haas DA, "A 21 year retrospective study of reports of paresthesia following local anesthetic administration", Journal (Canadian Dental Association), 61(4), pp.319~ (1995)
- Worthington P, "Injury to the inferior alveolar nerve during implant placement: a formula for protection of the patient and clinician", The InternationaL journal of oral & maxillofacial implants, 19(5), pp.731~ (2004)
- Sisk AL, "Complications following removal of impacted third molars: the role of the experience of the surgeon", Journal of oral and maxillofacial surgery, 44(11), pp.855~859 (1986)
- Lopes V, "Third molar surgery: an audit of the indications for surgery, post-operative complaints and patient satisfaction", British Journal of Oral and Maxillofacial Surgery, 33(1), pp.33~35 (1995)
- J R, "The split-bone technique for removal of impacted mandibular third molars", J Oral Surg, 28, pp.416~ (1970)
- Wofford DT, "Prospective study of dysesthesia following odontectomy of impacted mandibular third molars", Journal of oral and maxillofacial surgery, 45(1), pp.15~19 (1987)
- Valmaseda-Castellon E, "Inferior alveolar nerve damage after lower third molar surgical extraction: a prospective study of 1117 surgical extractions", Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontics, 92(4), pp.377~383 (2001)
- Gulicher D, "Sensory impairment of the lingual and inferior alveolar nerves following removal of impacted mandibular third molars", International journal of oral and maxillofacial surgery, 30(4), pp.306~312 (2001)
- Kipp DP, "Dysesthesia after mandibular third molar surgery: a retrospective study and analysis of 1,377 surgical procedures", Journal of the American Dental Association, 100(2), pp.185~ (1980)
- van Steenberghe D, "Applicability of osseointegrated oral implants in the rehabilitation of partial edentulism: a prospective multicenter study on 558 fixtures", The International journal of oral & maxillofacial implants, 5(3), pp.272~ (1990)
- Ellies LG, "Altered sensation following mandibular implant surgery: a retrospective study", The Journal of Prosthetic Dentistry, 68(4), pp.664~671 (1992)
- Ellies LG, "The prevalence of altered sensation associated with implant surgery", The International journal of oral & maxillofacial implants, 8(6), pp.674~ (1993)
- Bartling R, "The incidence of altered sensation of the mental nerve after mandibular implant placement* 1", Journal of oral and maxillofacial surgery, 57(12), pp.1408~1410 (1999)
- Hirsch JM, "Fixture stability and nerve function after transposition and lateralization of the inferior alveolar nerve and fixture install ation", British Journal of Oral and Maxillofacial Surgery, 33(5), pp.276~281 (1995)
- Nakagawa K, "Somatosensory-evoked potential to evaluate the trigeminal nerve after sagittal split osteotomy", Oral Surgery, Oral Medicine, Oral Pathology. Oral Radiology & Endodontics, 91(2), pp.146~152 (2001)
- Jaaskelainen S, "Lehtinen R: The mental nerve blink reflex in the diagnosis of lesions of the inferior alveolar nerve following orthognathic surgery of the mandible", British Journal of Oral and Maxillofacial Surgery, 34(1), pp.87~95 (1996)
- Nakagawa K, "The assessment of trigeminal sensory nerve paraesthesia after bilateral sagittal split osteotomy: modified somatosensory evoked potentials recording method", Journal of Cranio-Maxillofacial Surgery, 25(2), pp.97~101 (1997)
- August M, "Neurosensory deficit and functional impairment after sagittal ramus osteotomy: A long-term follow-up study* 1", Journal of oral and maxillofacial surgery, 56(11), pp.1231~1235 (1998)
- Becelli R, "Inferior alveolar nerve impairment after mandibular sagittal split osteotomy: An analysis of spontaneous recovery patterns observed in 60 patients", Journal of Craniofacial Surgery, 13(2), pp.315~ (2002)
- Yoshida T, "Impairment of the inferior alveolar nerve after sagittal split osteotomy", Journal of Cranio-Maxillofacial Surgery, 17(6), pp.271~277 (1989)
- Akal UK, "Evaluation of the neurosensory deficiencies of oral and maxillofacial region following surgery", International journal of oral and maxillofacial surgery, 29(5), pp.331~336 (2000)
- Panula K, "Neurosensory deficits after bilateral sagittal split ramus osteotomy of the mandibleinfluence of soft tissue handling medial to the ascending ramus", International journal of oral and maxillofacial surgery, 33(6), pp.543~548 (2004)
- Westermark A, "Inferior alveolar nerve function after mandibular osteotomies", British Journal of Oral and Maxillofacial Surgery, 36(6), pp.425~428 (1998)
- Nesari S, "Neurosensory function of the inferior avLeoLar nerve after bi1ateral sagittaL ramus osteotomy: a retrospective study of 68 patients", International journal of oral and maxillofacial surgery, 34(5), pp.495~498 (2005)
- Westermark A, "Inferior alveolar nerve function after sagittal split osteotomy of the mandible: correlation with degree of intraoperative nerve encounter and other variables in 496 operations", British Journal of Oral and Maxillofacial Surgery, 36(6), pp.429~433 (1998)
- Pratt C, "Labial sensory function following sagittal split osteotomy", British Journal of Oral and Maxillofacial Surgery, 34(1), pp.75~81 (1996)
- Jaaskelainen SK, "Evaluating function of the inferior alveolar nerve with repeated nerve conduction tests during mandibular sagittal split osteotomy* 1", Journal of oral and maxillofacial s, 53(3), pp.269~279 (1995)
- Seddon H, "Three types of nerve injury", Brain, 66(4), pp.237~ (1943)
- Sunderland S, "A classification of peripheral nerve injuries producing loss of function", Brain, 74(4), pp.491~ (1951)
- Jurecka W, "Regeneration of a transected peripheral nerve", Acta neuropathologica, 32(4), pp.299~312 (1975)
- Faweett J, "Peripheral nerve regeneration", Annual review of neuroscience, 13(1), pp.43~60 (1990)
- Nissl F, "Uber die Veranderungen der Ganglienzellen am Facialiskern des Kaninchens nach Ausreissung der Nerven", Allg. Z. Psychiat, 48, pp.197~198 (1892)
- Dahlin L, "The neurone and its response to peripheral. nerve compression", The Journal of Hand Surgery: Journal of the British Society for Surgery of the Hand, 15(1), pp.5~10 (1990)
- Evans D, "Cytology of Nervous Tissue", pp.71~ (1961), Taylor and Francis Ltd.
- Takano I, "Electron microscopic studies on retrograde chromotolysis in the hypoglossal nucleus and changes in the hypoglossal nerve. following its seve rence and ligation", Okajimas folia anatomica Japonica, 40, pp.1~ (1964)
- Matthews MR, "A light and electron microscopic study of the cellular response to axonal injury in the superior cervical ganglion of the rat", Proceedings of the Royal Society of London. Series B. Biological Sciences, pp.43~79 (1972)
- Grafstein B, "The nerve cell body response to axotomy", Experimental neurology, 48(3 pt. 2), pp.32~ (1975)
- Lieberman A, "The axon reaction: a review of the principal features of perikaryal responses to axon injury", Int Rev Neurobiol, 14(4), pp.124~ (1971)
- Tetzlaff W, "Response of facial and rubrospinal neurons to axotomy: changes in mRNA expression for cytoskeletal proteins and GAP-43", The Journal of neuroscience, 11(8), pp.2528~ (1991)
- Skene JHP, "Axonal growthassociated proteins", Annual review of neuroscience, 12(1), pp.127~156 (1989)
- Zelena J, "Neurofilaments and microtubules in sensory neurons after peripheral nerve section", Cell and Tissue Research, 117(2), pp.191~211 (1971)
- Hoffman PN, "Expression of GAP-43. a rapidly transported growthassociated protein. and class II beta tubulin. a slowly transported cytoskeletal protein. are coordinated in regenerating neurons", The Journal of neuroscience, 9(3), pp.893~ (1989)
- Weiss P, "Experiments on the mechanism of nerve growth", Journal of experimental zoology, 107(3), pp.315~395 (1948)
- Theiler R, "Rapid axoplasmic transport of proteins in regeneratíng sensory nerve fibers", Journal of Neurochemistry, 31(2), pp.433~447 (1978)
- McKerracher L, "Slow transport of the cytoskeleton after axonal injury", Journal of neurobiology, 23(5), pp.568~578 (1992)
- Hendry I, "The retrograde axonal transport of nerve growth factor", Brain research, 68(1), pp.103~121 (1974)
- Holmes W, "Nerve regeneration after immediate and delayed suture", Journal of Anatomy, 77(Pt 1), pp.63~ (1942)
- Stoll G, "Nerve injury. axonal degeneration and neural regeneration: basic insights", Brain pathology, 9(2), pp.313~325 (1999)
- Thomas P, "The cellular response to nerve injury. 1. The cellular outgrowth from the distal stump of transected nerve", Journal of Anatomy, 100(Pt 2), pp.287~ (1966)
- Thomas P, "The cellular response to nerve injury. 3. The effect of repeated crush injuries", Journal of Anatomy, 106(Pt 3), pp.463~ (1970)
- Fu SY, "Contributing fadors to poor functional recovery after delayed nerve repair: prolonged axotomy", The Journal of neuroscience, 15(5), pp.3876~ (1995)
- Thomas P, "Changes in the endoneurial sheaths of peripheral myelinated nerve fibres during Wallerian degeneration", Journal of Anatomy, 98(Pt 2), pp.175~ (1964)
- OHARA S, "Schwann cell responses during regeneration after one or more crush injuries to myelinated nerve fibres", Neuropathology and applied neurobiology, 14(3), pp.229~245 (1988)
- Ide C, "Schwann cell basal lamina and nerve regeneration", Brain research, 288(1-2), pp.61~75 (1983)
- Cornbrooks C, "In vivo and in vitro observations on laminin production by Schwann cells", Proceedings of the National Academy of Sciences, 80(12), pp.3850~ (1983)
- Wang GY, "The role of laminin, a component of Schwann cell basal lamina, in rat sciatic nerve regeneration within antiserumtreated nerve grafts", Brain research, 570(1-2), pp.116~125 (1992)
- Weinberg HJ, "The fate of Schwann cells isolated from axonal contact", Journal of neurocytology, 7(5), pp.555~569 (1978)
- Agthong S, "Activation of MAPK ERK in peripheral nerve after injury", BMC neuroscience, 7(1), pp.45~ (2006)
- Bhatheja K, "Schwann cells: origins and role in axonal maintenance and regeneration", The International Journal of Biochemistry & Cell Biology, 38(12), pp.1995~1999 (2006)
- Taniuchi M, "Induction of nerve growth factor receptor in Schwann cells after axotomy", Proceedings of the National Academy of Sciences, 83(11), pp.4094~ (1986)
- Funakoshi H, "Differential expression of mRNAs for neurotrophins and their receptors after axotomy of the sciatic nerve", The Journal of cell biology, 123(3), pp.455~ (1993)
- von Frey M, "Untersuchungen uber die Sinnesfunctionen der menschlichen Haut" (1896), S. Hirzel
- Robinson P, "Equipment and methods for simple sensory testing", British Journal of Oral and Maxillofacial Surgery, 30(6), pp.387~389 (1992)
- Campbell RL, "Assessment of recovery from injury to inferior alveolar and mental nerves", Oral Surgery, Oral Medicine, Oral Pathology, 64(5), pp.519~526 (1987)
- Semmes J, "Somatosensory changes after penetrating brain wounds in man", ~ (1960)
- Bell-Krotoski J, "Threshold detection and Semmes-Weinstein monofilaments", Journal of hand therapy: official journal of the American Society of Hand The rapists, 8(2), pp.155~ (1995)
- Bell-Krotoski J, "The repeatability of testing with Semmes-Weinstein monofilaments", The Journal of hand surgery, 12(1), pp.155~ (1987)
- Dellon AL, "The vibrometer", Plastic and Reconstructive Surgery, 71(3), pp.427~ (1983)
- Dellon AL, "Clinical use of vibratory stimuli to evaluate peripheral nerve injury and compression neuropathy", Plastic and Reconstructive Surgery, 65(4), pp.466~ (1980)
- Novak CB, "Evaluation of nerve injury and nerve compression in the upper quadrant", Journal of Hand Therapy, 18(2), pp.230~240 (2005)
- Dyck PJ, "Description of "Minnesota Thermal Disks" and normal values of cutaneous thermal discrimination in man", Neurology, 24(4), pp.325~ (1974)
- Jaaskelainen SK, "A new technique for recording sensory conduction velocity of the inferior alveolar nerve", Muscle & nerve, 22(4), pp.455~459 (1999)
- Barker G, "Applications of trigeminal somatosensory evoked potentials (TSEPs) in oral and maxillofacial surgery", British Journal of Oral and Maxillofacial Surgery, 25(4), pp.308~313 (1987)
- Ghali GE, "Somatosensory evoked potential assessment of the inferior alveolar nerve following third molar extraction", International journal of oral and maxillofacial surgery, 19(1), pp.18~21 (1990)
- Kim HS, "Reliability and characteristics of current perception thresholds in the territory of the infraorbital and inferior alveolar nerves", Journal of orofacial pain, 14(4), pp.286~ (2000)
- Gratt BM, "Electronic thermography for the assessment of inferior alveolar nerve deficitl", Oral Surgery, Oral Medicine, Oral Pathology, Oral Racliology, and Endodontology, 80(2), pp.153~160 (1995)
- Biagioni P, "lnfrared thermography. lts role in dental research with particular reference to craniomandibular disorders", Dentomaxillofacial Radiology, 25(3), pp.119~ (1996)
- Fischer A, "Value of thermography in diagnosis of radiculopathy as compared with electrocliagnosis", Arch Phys Med Rehabil, pp.64526~ (1983)
- Brelsford KL, "Uematsu 3: Thermographic presentation of cutaneous sensory and vasomotor activity in the injured peripheral nerve", Journal of neurosurgery, 62(5), pp.711~715 (1985)
- Gratt B, "Thermography for the clinical assessment of inferior alveolar nerve deficit: a pilot study", Journal of orofacial pain, 8(4), pp.369~ (1994)
- Kaechi K, "Pharmacological induction of physiologically active nerve growth factor in rat peripheral nervous system", Journal of Pharmacology and Experimental Therapeutics, 264(1), pp.321~ (1993)
- Khullar SM, "The effects of low level laser treatment on recovery of nerve conduction and motor function after compression injury in the rat sciatic nerve", European journal of oral sciences, 103(5), pp.299~305 (1995)
- Khullar SM, "Preliminary study of low- level laser for treatment of long-stancling sensory aberrations in the inferior alveolar nerve* 1", Journal of oral and maxillofacial surgery, 54(1), pp.2~7 (1996)
- Khullar SM, "Effect of low-level laser treatment on neurosensory deficits subsequent to saggittal split ramus osteotomy", Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 82(2), pp.132~138 (1996)
- Donoff RB, "Surgical management of inferior alveolar nerve injuries. I: The case for early repair", Journal of oral and maxillofacial surgery, 53(11), pp.1327~1329 (1995)
- "Refu’at ha-peh veha-shinayim", 1993, 44~
- Ghali G, "Clinical neurosensory testing: practical applications", Journal of oral and maxillofacial surgery, 47(10), pp.1074~1078 (1989)
- TERZIS JK, "Microsurgery of the peripheral nerve: a physiological approach", Clinical Orthopaedics and Related Research, 133, pp.39~ (1978)
- Orgel M, "Epineural Versus Perineural Repair", Plast. Reconstr. Surg, 60, pp.80~ (1977)
- Svane TJ, "Fascicular characteristics of the human inferior alveolar nerve**", Journal of oral and maxillofacial surgery, 44(6), pp.431~434 (1986)
- Svane T, "The fascicular characteristics of human inferior alveolar and greater auricular nerves", master’s, pp.1989
- Wessberg GA, "Experiences with microsurgical reconstruction of the inferior alveolar nerve", Journal of oral and maxillofacial surgery, 40(10), pp.651~655 (1982)
- HAUSAMEN JE, "Restoring sensation to the cut inferior alveolar nerve by direct anastomosis or by free autologous nerve grafting", Plastic and Reconstructive Surgery, 54(1), pp.83~ (1974)
- Noma H, "Repair of the mandibular nerve by autogenous grafting after partial resection of the mandible", Journal of oral and maxillofacial surgery, 44(1), pp.31~36 (1986)
- Miloro M, "Subjective outcomes following sural nerve harvest", Journal of oral and maxillofacial surgery, 63(8), pp.1150~1154 (2005)
- Hausaman J, "Course attended and material presented-microsurgery course", pp.1983
- Wolford LM, "Considerations in nerve repair", Proceedings (Baylor University, Medical Center), 16(2), pp.152~ (2003)
- Francel PC, "Enhancing nerve regeneration across a silicone tube conduit by using interposed short-segment nerve grafts", Journal of neurosurgery, 87(6), pp.887~892 (1997)
- Eppley BL, "Collagen tube repair of the mandibular nerve: a preliminary investigation in the rat", Journal of oral and maxillofacial surgery, 46(1), pp.41~47 (1988)
- Yamazaki Y, "Comparison of suture methods and materials in experimental inferior alveolar nerve grafting*", Journal of oral and maxillofacial surgery, 41(1), pp.34~46 (1983)
- Seckel BR, "Nerve regeneration through synthetic biodegradable nerve guides: regulation by the target organ", Plastic and Reconstructive Surgery, 74(2), pp.173~ (1984)
- Chiu D, "Autogenous vein graft as a conduit [or nerve regeneration", Surgery, 91(2), pp.226~ (1982)
- Wang KK, "Sleeve insertion and collagen coating improve nerve regeneration through vein conduits", Journal of reconstructive microsurgery, 9, pp.39~39 (1993)
- Itoh S, "Experimental study on nerve regeneration through the basement membrane tubes of the nerve. muscle. and artery", Microsurgery, 17(10), pp.525~534 (1996)
- Pogrel MA, "Gore-Tex tubing as a conduit for repair of lingual and inferior alveolar nerve continuity defects : a preliminary report", Journal of oral and maxillofacial surgery, 56(3), pp.319~321 (1998)
- Strauch B, "Determining the maximal length of a vein conduit used as an interposition graft for nerve regeneration", Journal of reconstructive microsurgery, 12, pp.521~528 (1996)
- Chiu DTW, "A prospective clinica1 evaluation of autogenous vein grafts used as a nerve conduit for distal sensory nerve defects of 3 cm or less", Plastic and Reconstructive Surgery, 86(5), pp.928~ (1990)
- VALENTINI RF, "Patterned neuronal attachment and outgrowth on surface modified, electrically charged tluoropolymer substrates", Polymer Biomaterials in Solution, As Interfaces And As Solids: A Festschrift Honoring the 60th Birthday of Dr. Allan S. Hoffman, 69 (1995)
- Valentini RF, "Electrically charged polymeric substrates enhance nerve fibre outgrowth in vitro", Biomaterials, 13(3), pp.183~190 (1992)
- Fine EG, "Improved nerve regeneration through piezoelectric vinylidenetluoridetritluoroethylene copolymer guidance channels", Biomaterials, 12(8), pp.775~780 (1991)
- Guénard V, "Influence of surface texture of polymeric sheets on peripheral nerve regeneration in a two-compartment guidance system", Biomaterials, 12(2), pp.259~263 (1991)
- Martini R, "Expression and functional roles of neural cell surface molecules and extracellular matrix components during development and regeneration of peripheral nerves", Journal of neurocytology, 23(1), pp.1~ (1994)
- 135, "Regeneration and repair of the peripheral nervous system", Paper presented at (1993)
- Rodríguez FJ, "Nerve guides seeded with autologous Schwann cells improve nerve regeneration", Experimental neurology, 161(2), pp.571~584 (2000)
- Tuszynski MH, "Grafts of genetically modified Schwann cells to the spinal cord: survival, axon growth, and myelination", Cell transplantation, 7(2), pp.187~196 (1998)
- Feltri ML, "Mitogen-expanded Schwann cells retain the capacity to myelinate regenerating axons after transplantation into rat sciatic nerve", Proceedings of the National Academy of Sciences, 89(18), pp.8827~ (1992)
