건강 검진자 중 B형 간염 바이러스의 표면항원과 항체의 양성률

Abstract

Hepatitis B virus(HBV) infection is prevalent in all parts of the world, with the highest incidence in Southeast Asia and Africa. Acute HBV infection is fully resolved in 90% to 95% of infected adults, who remain immune for their lifetimes. It is estimated that more than 350 million people in the world are chronic carriers. HBV carriers are at risk for developing chronic liver disease, including hepatocellular carcinoma. The aim of this study was performed to survey of the current tendency of HBV infection in Korea. A total number of 1,818 serum samples(male 1,292, female 526) collected from the health promotion center in Wonkwang University, School of Medicine and Hospital had been tested to detect for hepatitis B surface antigen(HBsAg) and anti-HBs by enzyme-linked immunosorbent assay(ELISA) method during the period March, 2002 to May, 2003. The positive rate for HBsAg was 4.5%(82/1,818), and that of male was 5.0% higher than female 3.2%. The positive rate of HBsAg by age group was the highest positive rate group in 40-49 years(6.1%), and upper 60 years(2.2%) was lowest of all. The positive rate for anti-HBs was 66.7%(1,212/1,818), and positive rate of female(66.9%) and male(66.6%) showed similar results. The positive rate of anti-HBs by age group was the highest positive rate group in 30-39 years(69.3%), and upper 60 years(59.8%) was lowest rate of all.