본문 바로가기
KERD
논문KCI 등재

뇌졸중 환자의 동맥경직도에 따른 임상검사결과와 유병률의 비교

Comparison of Clinical Laboratory Data and Prevalence according to Arterial Stiffness in Stroke Patients

0

조회

0

다운로드

2

인용

0

참고문헌

키워드

주제분류기타자연과학

초록

Pulse wave velocity (PWV) is used to non-invasively estimate the severity of arteriosclerosis by measuring the patient's arterial stiffness comparing with each normal reference range according to their ages. Increased arterial stiffness is closely related to both atherosclerosis and arteriosclerosis, which have been known for causes of cardiovascular disease and stroke, also negatively affects the prognosis and the re-occurrence in patients with stroke. The study is focused on how brachial-ankle pulse wave velocity (baPWV) is related to cardiovascular disease risk factors in patients with acute stroke. There were 114 subjects, 69 males and 45 females, all in their 60's and had PWV test for acute stroke. The results are as follows: the group with increased arterial stiffness showed significant increase in HbAlc, total cholesterol, RSBP (resting systolic blood pressure), CSBP (central systolic blood pressure) and CDBP (central diastolic blood pressure). Cross tabulation test showed that there was a significant relationship only between the group with increased arterial stiffness and diabetes mellitus (DM). Therefore, it might be useful for preventing re-occurrence and making a favorable prognosis to promptly adjust DM and hypertension-related risk factors in patients with acute stroke.

Abstract

Pulse wave velocity (PWV) is used to non-invasively estimate the severity of arteriosclerosis by measuring the patient's arterial stiffness comparing with each normal reference range according to their ages. Increased arterial stiffness is closely related to both atherosclerosis and arteriosclerosis, which have been known for causes of cardiovascular disease and stroke, also negatively affects the prognosis and the re-occurrence in patients with stroke. The study is focused on how brachial-ankle pulse wave velocity (baPWV) is related to cardiovascular disease risk factors in patients with acute stroke. There were 114 subjects, 69 males and 45 females, all in their 60's and had PWV test for acute stroke. The results are as follows: the group with increased arterial stiffness showed significant increase in HbAlc, total cholesterol, RSBP (resting systolic blood pressure), CSBP (central systolic blood pressure) and CDBP (central diastolic blood pressure). Cross tabulation test showed that there was a significant relationship only between the group with increased arterial stiffness and diabetes mellitus (DM). Therefore, it might be useful for preventing re-occurrence and making a favorable prognosis to promptly adjust DM and hypertension-related risk factors in patients with acute stroke.

참고문헌 (19)

  1. Blacher J, "Aortic pulse wave velocity as a marker of cardiovascular risk in hypertensive patients", Hypertension, 33, pp.1111~1117 (1999)
  2. Boutouyrie P, "Aortic stiffness is an independent predictor of primary coronary events in hypertensive patients: A longitudinal study", Hypertension, 39, pp.10~15 (2002)
  3. Choi JC, "Limitation of brachial-ankle pulse wave velocity in assessing the risk of stroke:Importance of instantaneous blood pressure", Cerebrovasc Dis, 27, pp.417~425 (2009)
  4. Expert Committee on the Diagnosis and Classification of Diabetes Mellitus, "Report of the expert committee on the diagnosis and classification of diabetes mellitus", Diabetes Care, 26(Suppl1), pp.S5~S20 (2003)
  5. Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults, "Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP)Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III)", JAMA, 285(19), pp.2486~2497 (2001)
  6. Franklin SS, "Is pulse pressure useful in predicting risk for coronary heart disease? The Framingham Heart Study", Circulation, 100, pp.354~360 (1999)
  7. Hamilton PK, "Arterial stiffness: Clinical relevance, measurement and treatment", Clin Sci(Lond), 100, pp.387~393 (2011)
  8. Izzo JL, "Arterial stiffness and the systolic hypertension syndrome", Curr Opin Cardiol, 19, pp.341~352 (2004)
  9. Jones DW, "Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure and evidence from new hypertension trials", Hypertension, 43(1), pp.1~3 (2004)
  10. Kim J, "The association between cerebral atherosclerosis and arterial stiffness in acute ischemic stroke", Atherosclerosis, 219(2), pp.887~891 (2011)
  11. Laurent S, "Recent advances in arterial stiffness and wave reflection in human hypertension", Hypertension, 49, pp.1210~1206 (2007)
  12. Laurent S, "Aortic stiffness is an independent predictor of fatal stroke in essential hypertension", Stroke, 34, pp.1203~1206 (2003)
  13. McLeod AL, "Non-invasive measures of pulse wave velocity correlate with coronary arterial plaque load in humans", J Hypertens, 22, pp.363~368 (2004)
  14. Motobe K, "Cut-off value of the ankle-brachial pressure index at which the accuracy of brachial-ankle pulse wave velocity measurement is diminished", Circulation journal : official journal of the Japanese Circulation Society, 69(1), pp.55~60 (2005)
  15. 이무용, "Acute and Chronic Effects of Smoking on the Arterial Wall Properties and the Hemodynamics in Smokers with Hypertension", Korean Circulation Journal, 35(7), pp.493~499 (2005), 대한심장학회
  16. Seo WK, "Cerebral microbleeds are independently associated with arterial stiffness in stroke patients", Cerebrovasc Dis, 26(6), pp.618~623 (2008)
  17. Zieman SJ, "Mechanisms, pathophysiology, and therapy of arterial stiffness", Arterioscler Thromb Vasc Biol, 25, pp.932~943 (2005)
  18. 박진식, "침습적으로 측정한 대동맥 맥파전파속도와 관상동맥 질환의 관계", Korean Circulation Journal, 35(10), pp.766~772 (2005), 대한심장학회
  19. 조주희, "맥파전파속도와 경동맥 내막-중막 두께 및 경동맥 확장도와의 상관관계", Journal of Cardiovascular Ultrasound, 14(3), pp.92~97 (2006), 한국심초음파학회

관련 논문AI추천

이 간행물의 다른 논문 (6건)