Relationship between the Estimated Glomerular Filtration Rate and the Urine Microalbumin/Creatinine Ratio and Ferritin in Korean Adults
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초록
This study examined the relationship between the estimated glomerular filtration rate (eGFR) and urine microalbumin/creatinine ratio (uACR) with ferritin in Korean adults. This study included 4,948 adults aged ≥20 years from the 2012 Korea National Health and Nutrition Examination Survey (KNHANES) data. A covariance test adjusted for covariates was performed for the ferritin levels in relation to the decreased eGFR (eGFR＜60 ml/min/1.73 m2) and elevated uACR (uACR≥30 mg/g). Several key findings were made in the present study. First, after adjusting for the related variables, the ferritin level was higher in the decreased eGFR group [103.04±6.59 mL/min/1.73 m2; 95% confidence interval (CI), 90.12∼115.96] than in the normal eGFR group (84.87±1.16 mL/min/1.73 m2; 95% CI, 82.59∼87.14; P=0.007). Second, after adjusting for the related variables, the ferritin level (M±SE) was similar in the normal uACR group (85.70±1.20 mg/g; 95% CI, 83.35∼88.05) and elevated uACR group (82.72±4.09 mg/g; 95% CI, 74.71∼90.73) (P=0.487). Chronic kidney disease was positively associated with the ferritin level in Korean adults but albuminuria was not.
Abstract
This study examined the relationship between the estimated glomerular filtration rate (eGFR) and urine microalbumin/creatinine ratio (uACR) with ferritin in Korean adults. This study included 4,948 adults aged ≥20 years from the 2012 Korea National Health and Nutrition Examination Survey (KNHANES) data. A covariance test adjusted for covariates was performed for the ferritin levels in relation to the decreased eGFR (eGFR＜60 ml/min/1.73 m2) and elevated uACR (uACR≥30 mg/g). Several key findings were made in the present study. First, after adjusting for the related variables, the ferritin level was higher in the decreased eGFR group [103.04±6.59 mL/min/1.73 m2; 95% confidence interval (CI), 90.12∼115.96] than in the normal eGFR group (84.87±1.16 mL/min/1.73 m2; 95% CI, 82.59∼87.14; P=0.007). Second, after adjusting for the related variables, the ferritin level (M±SE) was similar in the normal uACR group (85.70±1.20 mg/g; 95% CI, 83.35∼88.05) and elevated uACR group (82.72±4.09 mg/g; 95% CI, 74.71∼90.73) (P=0.487). Chronic kidney disease was positively associated with the ferritin level in Korean adults but albuminuria was not.
참고문헌 (39)
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