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Relationship of Riboflavin and Niacin with Cardiovascular Disease

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초록

Cardiovascular disease is caused by different factors. These factors include innateness factors such as aging, biological factors such as high blood pressure, and environmental factors such as stress. This study examined the factors associated with cardiovascular disease and the ways to reduce its prevalence by analyzing the data within the Korean National Health and Nutrition Examination Reports from 2013 to 2017, and particularly the survey and examination data for people over 50 years old. The study population was divided into two groups: members of the first group consumed riboflavin and niacin at the recommended rate while those in the second group did not. Riboflavin intake was correlated with hypertension, hyperglycemia, and a low HDL-cholesterol level, whereas niacin intake was correlated with hypertension, hyperglycemia, waist size, and a low HDL-cholesterol level. The combination of niacin and riboflavin intakes was correlated with hypertension, hyperglycemia, waist size, and a low HDL-cholesterol level (P<0.05). The combined intake of the recommended levels of riboflavin and niacin reduced the average physiological factor abnormality rate to 80%. Taken together, the beneficial effects of riboflavin and niacin can reduce the prevalence of cardiovascular disease.

Abstract

Cardiovascular disease is caused by different factors. These factors include innateness factors such as aging, biological factors such as high blood pressure, and environmental factors such as stress. This study examined the factors associated with cardiovascular disease and the ways to reduce its prevalence by analyzing the data within the Korean National Health and Nutrition Examination Reports from 2013 to 2017, and particularly the survey and examination data for people over 50 years old. The study population was divided into two groups: members of the first group consumed riboflavin and niacin at the recommended rate while those in the second group did not. Riboflavin intake was correlated with hypertension, hyperglycemia, and a low HDL-cholesterol level, whereas niacin intake was correlated with hypertension, hyperglycemia, waist size, and a low HDL-cholesterol level. The combination of niacin and riboflavin intakes was correlated with hypertension, hyperglycemia, waist size, and a low HDL-cholesterol level (P<0.05). The combined intake of the recommended levels of riboflavin and niacin reduced the average physiological factor abnormality rate to 80%. Taken together, the beneficial effects of riboflavin and niacin can reduce the prevalence of cardiovascular disease.

참고문헌 (39)

  1. 고혜진, "정상 범위 내의 혈청 Gamma-glutamyltransferase와 심혈관 질환의 위험요인과의 관련성: Framingham Risk Score를 중심으로", Journal of Obesity & Metabolic Syndrome, 22(1), pp.21~29 (2013), 대한비만학회
  2. Youn SI, "SNP study of the endothelial NO Synthase as risk factor for cardiovascular diseases in Koreans", Report of National Institute of Health, 37, pp.400~404 (2000)
  3. 이승원, "Thirty-Year Trends in Mortality from Cardiovascular Diseases in Korea", Korean Circulation Journal, 45(3), pp.202~209 (2015), 대한심장학회
  4. 수리주안, "성별에 따른 심혈관질환자의 건강행위에 미치는 요인", 한국콘텐츠학회 논문지, 15(3), pp.280~289 (2015), 한국콘텐츠학회[DOI]
  5. 조정진, "직무스트레스 요인과 심혈관질환위험요인 및 대사증후군", Annals of Occupational and Environmental Medicine, 18(3), pp.209~220 (2006), 대한직업환경의학회
  6. Jee SH, "Development of the individualized health risk appraisal model of ischemic heart disease risk in Korea", J Lipid Atheroscler, 14, pp.153~168 (2004)
  7. Hoppel C, "Riboflavin and rat hepatic cell structure and function, mitochondrial oxidative metabolism in deficiency states", J Biol chem, 254, pp.4164~4170 (1979)
  8. Sugioka G, "The liver of rats fed riboflav in-deficient diet at two levels of protein", Am J Pathol, 54, pp.1~19 (1969)
  9. Mielgo-Ayuso J, "Dietary intake and food sources of niacin, riboflavin, thiamin and vitamin B6 in a representative sample of the Spanish population. The ANIBES Study", Nutrients, 10, pp.846~ (2018)
  10. Zhang LH, "Niacin inhibits surface expression of ATP synthase  chain in HepG2 cells : implications for raising HDL", J Lipid Res, 49, pp.1195~1201 (2008)
  11. Braun MM, "Stable coronary artery disease : treatment", Am Fam Physician, 97, pp.376~384 (2018)
  12. Pisarik P, "Evidence supporting niacin therapy is more nuanced than article states", Am Fam Physician, 98, pp.630~631 (2018)
  13. Choi JY, "Evaluation of riboflavin intakes and status of 20–64-year-old adults in South Korea", Nutrients, 7, pp.253~264 (2015)
  14. Kweon S, "Data resource profile : the Korea National Health and Nutrition Examination Survey(KNHANES)", Int J Epidemiol, 43, pp.69~77 (2014)
  15. "Metabolic syndrome" (2016)[URL]
  16. "Dietary reference intakes for Koreans" (2019)[URL]
  17. Mendis S, "Global atlas on cardiovascular disease. Prevention and control. The World Health Organization in collaboration with the World Heart Federation and the World Stroke Organization", Geneva, Switzerland, 1, pp.1~153 (2011)
  18. 김응두, "Association of Abdominal Aortic Calcification with Lifestyle and Risk Factors of Cardiovascular Disease", Korean Journal of Family Medicine, 34(3), pp.213~220 (2013), 대한가정의학회
  19. Mozaffarian D, "Heart disease and stroke statistics-2015 update a report from the American heart association", Circulation, 131, pp.E29~322 (2015)
  20. Abramson BL, "Cardiovascular risk in women : focus on hypertension", Can J Cardiol, 30, pp.553~559 (2014)
  21. Peter SA, "Diabetes as a risk factor for stroke in women compared with men : a systematic review and meta-analysis of 64 cohorts, including 775, 385 individuals and 12, 539 strokes", Lancet, 383, pp.1973~1980 (2014)
  22. 배연희, "한국 30세 이상 성인의 심혈관계 질환의 위험 요인", 대한통합의학회지, 4(2), pp.97~107 (2016), 대한통합의학회
  23. Toth PP, "High-density lipoproteins : A consensus statement from the national lipid association", J Clin Lipidol, 7, pp.484~525 (2013)
  24. Goff DC, "2013 ACC", AHA guideline on the assessment of cardiovascular risk : A report of the American college of cardiology, J Am Coll Cardiol, pp.2014, 1[DOI]
  25. Ridker PM, "LDL cholesterol : controversies and future therapeutic directions", Lancet, 16, pp.607~617 (2014)
  26. Huxley R, "Cholesterol, coronary heart disease and stroke: a review of published evidence from observational studies and randomized controlled trials", Semin Vasc Med, 2, pp.315~323 (2002)
  27. Ragland DR, "Coronary heart disease mortality in the western collaborative group study, follow-up experience of 22 years", Am J Epidemiol, 127, pp.462~475 (1988)
  28. Jeppesen J, "Triglyceride concentration and ischemic heart disease : an eight-year follow-up in the copenhagen male study", Circulation, 97, pp.1029~1036 (1998)
  29. Patel A, "Serum triglycerides as a risk factor for cardiovascular diseases in the Asia-Pacific region", Circulation, 110, pp.2078~2086 (2004)
  30. Park JK, "The case-control study on the risk factors of cerebrovascular diseases and coronary heart diseases", J Prev Med Public Health, 29, pp.639~655 (1996)
  31. 신숙희, "우리나라 성인에서 혈청 지질성분비가 허혈성 심장질환 발생에 미치는 위험도 평가: 코호트 연구", 한국산학기술학회논문지, 13(5), pp.2219~2231 (2012), 한국산학기술학회[DOI]
  32. Jee SH, "Development of the individualized health risk appraisal model of ischemic heart disease risk in Korea", J Lipid Atheroscler, 14, pp.153~168 (2004)
  33. National Heart, Lung, and Blood Institute(NHLBI), "Epidemiology and prevention of cardiovascular disease" (1994), Bethesda
  34. 최민철, "제3기 국민건강영양조사를 바탕으로 살펴본 직업군별 Framingham risk score", Annals of Occupational and Environmental Medicine, 21(1), pp.63~75 (2009), 대한직업환경의학회
  35. 조은영, "한국인 남성에서의 CETP유전자 다형성이 혈중 지질농도 및 관상동맥질환의 발생에 미치는 영향.", Korean Circulation Journal, 34(6), pp.565~573 (2004), 대한심장학회
  36. D'Andrea E, "Assessment of the role of niacin in managing cardiovascular disease outcomes : a systematic review and meta-analysis", JAMA Netw Open, 2, pp.E192224~ (2019)
  37. Carretero OA, "Essential hypertension, part 1 : definition and etiology", Circulation, 101, pp.329~335 (2000)
  38. Cutler JA, "High blood pressure and end-organ damage", J Hypertens Suppl, 14, pp.3~6 (1996)
  39. "Payment data of health insurance Korea 2006∼2011" (2019)[URL]

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