고혈압 환자와 정상인의 혈청지질농도 및 체질량지수의 비교연구

Abstract

To assess the relationship between serum lipid concentration and hypertension, case control study were conducted. Hypertensive subjects(n = 54) and normotensive subjects(n = 41) were selected randomly from persons visited to the department of cardiac internal medicine, Wonkwang medical center between September 1994 and February 1995. Body surface area(BSA) , bodymass index(BMI) and percent ideal body weight(PIBW) were not significantly different between two groups. And there were no significant difference in total cholesterol, LDL cholesterol, atherogenic index , uric acid and urine protein concentration between two groups. In hypertensive group, serum triglyceride, VLDL cholesterol concentration, total cholesterol/HDL-cholesterol ratio and LDL-cholesterol/HDL-cholesterol ratio were significantly higher than normotensive group, but HDL-cholesterol was lower than normotensive group. This study demonstrates that the difference of serum lipid concentration between hypertensive patients and normotensive subject was determined by HDL cholesterol and VLDL cholesterol concentration.