시골에 사는 한국인의 비뇨기 요오드 배출에 대한 연구
The Study on the Urinary Iodine Excretion of Koreans Living in Rural Areas
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Abstract
More accurate evaluation of iodine consumption of Koreans can be made by measuring the urinary iodine excretion of people living in representative areas. The data about average iodine excretions by region, sex and age were gathered in order to suggest as a factor the criteria on the progress or prognosis of thyroid disease patients. This study was conducted on 3,000 subjects (2,000 Younggwang-gun residents and 1,000 Muan-gun residents) between July 2004 and August 2005. The data sampling was done based on stratified random sampling and the data were analyzed according to age (the subjects were divided into age groups, five years each) and sex of the subjects. Of the 3,000 subjects, a total of 1,592 people (1,174 in Younggwang-gun and 418 in Muan-gun) participated in this study, which used ISE (iodine ion selective electrode) to measure the concentration of iodine in urine. The 1,592 subjects are composed of 732 males and 860 females. The average urinary iodine excretion was 3.10±1.75 mg/L (0.31~15.2 mg/L). The average iodine excretion of males was 3.09±1.61 mg/L (0.42~15.2 mg/L) while it was 3.11±1.86 mg/L (0.31~12.5 mg/L) among females, which represents no significant difference between males and females. However, the values were significantly higher than those of Europeans and Americans. There were statistically significant differences among the regions. When the data were analyzed according to age, females in their 40s were found to have a little less urinary iodine excretion and males had less and less iodine excretion as they get older. These results are deemed to have a statistically significant difference. This study was conducted on a large number of people (N=1,592) for the first time in Korea. If the data collected through this study can be regarded as the average urinary iodine excretion of Koreans, it is possible to conclude that the average iodine consumptions of Koreans are a lot more than Europeans and Americans. Thus, the effect of much iodine consumption should be studied further.
참고문헌 (29)
- Baker DJP, "Current incidence of thyrotoxicosis and past prevalence of goiter in 12 British towns", Lancet (1984)
- Connoly RJ, "Increase in thyrotoxicosis in endemic goiter area after iodination of bread", Lancet, 1, pp.500~502 (1970)
- Cooper GJ, "Iodine in take in a urban environment: A study of urine iodide excretion in Auckland:Astudy of urine iodide excretion in Auckland", NZ Med J, 97, pp.142~145 (1984)
- Apractical guide to the correction of iodine deficiency. International council for control of iodine deficiency disorders, "Dunn JT", WHO, ~ (1990)
- Food and Nutrition Board, "National Research Council: Recommended dietary allowances", National of Sciences, ~ (1990)
- Frey HMM, "Value of single urine specimens in estimation of 24 hour urine iodine excretion", Acta Endocrinol, 72, pp.287~292 (1973)
- Jolin T, "Evaluation of iodine", creatinine ratios of casual samples of daily urinary iodine output during field studies, 1965, pp.25, 540~
- Kathleen L. Caldwell, "Urinary Iodine Concentration(United States National Health and Nutrition Examination Suvey 2001-2002)", Thyroid, 15(7) (2005)
- Kim JY, "Dietary Iodine Intake and Urinary Iodine Excretion in Normal Korean Adults", Yonsei Med J, 39, pp.355~362 (1998)
- Konno N, "Clinical evaluation of the Iodide", Creatinine ratio of casual urine samples as an index of daily iodide excretion in population study, 1993, pp.40, 163~169
- Nagataki S., "The thyroid", pp.306~ (1992)
- Park YK, "Estimation of dietary iodine intake of Americans in recent years", J Am Dietetic Assoc, 79, pp.17~24 (1981)
- Penningoton JT, "A review of iodine toxicity reports", J Am Dietetic Assoc, 90, pp.1571~1581 (1990)
- Stanbury JB, "Endemic goiter and endemic cretinism" (1980), Wiley & Sons
- Stanbury JB., "Iodine In Modern nutrition in health and disease", pp.227~237 (1989), Lee&Febiger
- Suzuki H, "Endemic coast goiter in Hokkaido, Japan", Acta Endocrinol, 50, pp.161~ (1965)
- Utiger RD, "The diverse effects of iodide on thyroid function", N Engl J Med, 287, pp.562~563 (1972)
- Van Leeuwen E., "En Vorm van genuine hyperthyeose nagebruik van gejadeed brood. Cited from Frndkin JE, Wolff J: Iodide induced thyrotoxicosis", Medidine, 62, pp.1~20 (1983)
- Vought RL, "Iodine intake, excretion and thyroidal accumulation in healthy subjects", J Clin Endocr, 27, pp.913~919 (1964)
- Wolff J., "Iodide goiter and Pharmacologic effect of excess iodide", Am J Med, 47, pp.101~124 (1969)
- 강태중, "옥소대사에 관한 연구. 제1편 한국인의 혈청단백결합옥소치와 뇨중 옥소배설양에 관한 연구", 대한내과학회잡지, 9, pp.363~ (1966)
- 김경래, "요오드와 갑상선질환", 대한내분비학회지, 9, pp.284~289 (1994)
- 김경래, "한국인 뇌하수체, 갑상선 및 부신의 형태계측학적 연구", 대한의학협회지, 31, pp.871~886 (1988)
- 김현만, "정상인 및 갑상선질환 환자에서 요중 요드배설량에 관한 연구", 대한내과학회지, 29, pp.625~631 (1985)
- 문수재, "요오드 전극을 이용한 방법과 중성자방사화에 의한 모유 및 요오드 함량 분석 방법 비교", Korean J Nutrition, 31, pp.212~219 (1998)
- 문수재, "한국인의 상용식품내 요오드 함량", Korean J Nutrition, 31, pp.206~212 (1998)
- 박혜영, "정상인 및 갑상선 질환 환자에서 요중 요드배설량에 관한 연구", 대한내분비학회지, 10, pp.386~394 (1995)
- 이종민, "전현성 갑상선질환의 진단 및 치료", Endocrinology and Metabolism, 17(3), pp.410~420 (2002), 대한내분비학회
- 장남수, "갑상선질환 환자의 요오드섭취량과 배설량", Korean J Nutrition, 27, pp.1037~1047 (1994)