한국 노인여성의 비만, 복부비만 기준에 따른 대사증후군 위험요인의 차이
The Differences of Metabolic Syndrome Risk Factors according to Obesity and Abdominal Obesity in Elderly Korean Women
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이 연구는 노인여성을 대상으로 비만, 복부비만 기준에 따른 대사증후군 위험요인의 차이를 알아보고, 비만 유형과 대사증후군 위험요인과의 관련성을 규명하고자 하였다. 비만 기준은 세계보건기구 아시아 태평양 기준에서 제시한 비만 기준을 따랐으며, 대사증후군은 The National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATP III)의 진단기준에 따라 분류하였다. 연구 대상자 591명 중 정상군 272명, 단순비만군 124명, 복부비만군 19명, 비만-복부비만군 176명 이었다. 비만, 복부비만기준에 따른 대사증후군 위험요인의 유병률 차이를 비교한 결과 낮은HDL-콜레스테롤혈증(p=0.009), 고중성지방혈증(p=0.025), 복부비만(p＜0.001), 대사증후군 진단 유병률(p＜0.001)은 집단간 차이를 보였으며, 비만-복부비만군에서의 유병률이 높게 나타났다. 로지스틱 회귀분석을 통해 복부비만 기준에 따른 비만유형과 대사증후군 각각의 위험요인 및 대사증후군 진단간의 관련성을 분석한 결과, 정상군에 비해 단순비만군에서 낮은 HDL-콜레스테롤혈증의발생이 1.6배 높았으며(odds ratio, OR: 1.576, 95% confidence interval, 95% CI: 1.006∼2.469), 비만-복부비만군에서는 1.9배높은 양상을 보였다(OR: 1.882, 95% CI: 1.266∼2.799). 고중성지방혈증은 정상군보다 비만-복부비만군에서 1.9배 높았다(OR: 1.904, 95% CI: 1.246∼2.910). 또한 정상군보다 복부비만군에서대사증후군 발생이 6.6배 높았으며(OR: 6.579, 95% CI: 2.233∼ 19.385), 비만-복부비만군의 경우 10.6배 높은 양상을 보였다(OR: 10.638, 95% CI: 6.053∼18.697).
Abstract
The study was performed to examine the metabolic syndrome risk factors in accordance with the obesity types based on body mass index (BMI) and waist circumference cutoffs. The diagnosis of metabolic syndrome closely adhered to the NCEP-ATP III criteria, and obesity was defined using the WHO Asian-Pacific criteria. We used the data from 591 elderly women, all aged over 65 years. They were divided into four groups: The normal group (n=272), the obesity group (n=124), abdominal obesity group (n=19), and obesity-abdominal obesity group (n=176). The obe-sity-abdominal obesity group was the most prevalent group of low HDL-cholesterol (p=0.009), hypertriglyceridemia (p=0.025), abdominal obesity (p＜0.001), and metabolic syndrome (p＜0.001). Logistic regression analysis demonstrated that the obesity-abdominal obesity group had the highest odds ratio in predicting metabolic syndrome (OR: 10.638, 95% CI: 6.053∼18.697). Therefore, the obesity-abdominal obesity group was the strongest predictive factor of metabolic syndrome risk in Korean elderly women.
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