비스페놀류의 사용 현황과 위해성: 소고
Current State of Use and the Risks of Bisphenols: A Minireview
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초록
비스페놀 A는 플라스틱과 에폭시 레진에 사용되는 대표 적인 내분비계 교란물질이다. BPA가 함유된 플라스틱은 물 병, 식품용기, CD, DVD, 그리고 건설현장에서 사용되는 건 축자재 등에 사용되고 있으며, BPA가 함유된 에폭시 레진은 상수도관 내의 코팅제, 식품용 캔 그리고 영수증용 감열지 등에 사용되고 있다. BPA의 에스트로젠 유사효과와 다른 유 해 영향이 많이 보고되고 있기 때문에 이미 많은 나라에서 BPA가 규제되고 있으며, BPA의 대체재를 만들기 위해 노력 중에 있다. 비스페놀 S와 비스페놀 F가 BPA의 대체재로 사 용되고 있으며, 최근에 BPS와 BPF가 함유된 제품들이 광범 위하게 소비되고 있다. 하지만, BPA와 비슷한 화학구조 때 문에 이 대체재들 또한 BPA처럼 내분비계의 교란을 일으키 며 이 대체재들의 유해 영향도 이미 많은 연구들을 통해 보 고되고 있는 실정이다. 본 소고에서 비스페놀류의 유해 영향 과 규제 현황을 기술하고자 한다.
Abstract
Bisphenol A (BPA), known as a typical endocrine disruptor, has been used commercially and widely for plastics and epoxy resins. BPA-based plastic is used extensively for the production of water bottles, food containers, CDs, DVDs, and panels that can be applied in construction. Epoxy resins containing BPA are used for coatings on the insides of water pipes, food cans, and thermal papers that are used in sales receipts. As its estrogenic effects and other adverse health effects have published, BPA has been regulated in many countries, and there have been efforts made to replace BPA. Other bisphenols substitutes such as bisphenol S (BPS) and bisphenol F (BPF) have been used. Currently, BPS- and BPF-based products labeled BPA-free products have been widely consumed. Because of structural similarities with BPA, however, these alternatives also show endocrine disruption effects like BPA, and many studies on adverse health effects of these alternatives are being reported. In this review, we describe the adverse health effects of bisphenols and the current status of regulation.
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