곰팡이 노출에 따른 건강영향 및 민감 시설 내 곰팡이 분포 현황
Health Effects of Exposure to Indoor Mold and the Levels of Mold in Facilities with Susceptible Populations in Korea
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초록
Objectives: Exposure to mold is strongly associated with adverse health effects (development or exacerbation of allergic diseases). We reviewed the health effects of mold exposure and explored to determine the annual distribution of indoor mold in facilities with susceptible populations. Methods: The health effects of mold exposure were mainly summarized by reviewing related papers and WHO research reports. We selected 10 facilities, including daycare centers, postpartum care centers, medical institutions, and elderly care facilities within the Seoul Metropolitan. Mold sampling was performed once every week or once every quarter from February 2016 to 2017. In addition, fungal species analyses was performed, and distribution status by month and facility was analyzed in the same manner as concentration. Results: Adverse health effects attributed to fungal exposure are largely divided into allergic symptoms, toxic effects, and infectious effects. Monthly mean concentrations of mold indoors and outdoors was 368.8 CFU/m3 (geometric mean 213.4 CFU/m3 ) and 496.0 CFU/m3 (327.9 CFU/m3 ), respectively. The indoor concentration has begun to increase in February, peaked in July, declined in August, increased again until October, and then decreased in November. About 36 genera of indoor fungal species were found in each facility. Cladosporium sp., Penicillium sp., Fusarium sp., Aspergillus sp., Alternaria sp., and Arthrinium sp. were observed as the dominant species. Conclusions: Our findings showed that the overall level of indoor mold was below the 500 CFU/m3 level recommended by the Ministry of Environment. The development of DNA-based assessment and expanding facilities to be monitored for mold would be necessary for preventive aspects.
Abstract
Objectives: Exposure to mold is strongly associated with adverse health effects (development or exacerbation of allergic diseases). We reviewed the health effects of mold exposure and explored to determine the annual distribution of indoor mold in facilities with susceptible populations. Methods: The health effects of mold exposure were mainly summarized by reviewing related papers and WHO research reports. We selected 10 facilities, including daycare centers, postpartum care centers, medical institutions, and elderly care facilities within the Seoul Metropolitan. Mold sampling was performed once every week or once every quarter from February 2016 to 2017. In addition, fungal species analyses was performed, and distribution status by month and facility was analyzed in the same manner as concentration. Results: Adverse health effects attributed to fungal exposure are largely divided into allergic symptoms, toxic effects, and infectious effects. Monthly mean concentrations of mold indoors and outdoors was 368.8 CFU/m3 (geometric mean 213.4 CFU/m3 ) and 496.0 CFU/m3 (327.9 CFU/m3 ), respectively. The indoor concentration has begun to increase in February, peaked in July, declined in August, increased again until October, and then decreased in November. About 36 genera of indoor fungal species were found in each facility. Cladosporium sp., Penicillium sp., Fusarium sp., Aspergillus sp., Alternaria sp., and Arthrinium sp. were observed as the dominant species. Conclusions: Our findings showed that the overall level of indoor mold was below the 500 CFU/m3 level recommended by the Ministry of Environment. The development of DNA-based assessment and expanding facilities to be monitored for mold would be necessary for preventive aspects.
참고문헌 (37)
- Bernstein JA, "The health effects of nonindustrial indoor air pollution", Journal of Allergy and Clinical Immunology, 121(3), pp.585~591 (2008)
- Douwes J, "Bioaerosol health effects and exposure assessment : progress and prospects", The Annals of Occupational Hygiene, 47(3), pp.187~200 (2003)
- Burge HA, "Bioaerosols" (1995), CRC Press
- Harris SD, "Cell polarity in filamentous fungi : shaping the mold", International Review of Cytology, 251, pp.41~77 (2006)
- Kuhn DM, "Indoor mold, toxigenic fungi, and Stachybotrys chartarum : infectious disease perspective", Clinical Microbiology Reviews, 16(1), pp.144~172 (2003)
- Clark N, "Damp indoor spaces and health" (2004), Institute of Medicine of the National Academies
- Robbins CA, "Health effects of mycotoxins in indoor air : a critical review", Applied Occupational and Environmental Hygiene, 15(10), pp.773~784 (2000)
- Seo S-C, "Development and Application of a New Methodology for Separation and Analysis of Submicrometer-Sized Fungal Particles in Laboratory and Field Study", pp.2007
- Reponen T, "Fungal fragments in moldy houses : a field study in homes in New Orleans and Southern Ohio", Atmospheric Environment, 41(37), pp.8140~8149 (2007)
- Seo S, "The level of submicron fungal fragments in homes with asthmatic children", Environmental Research, 131, pp.71~76 (2014)
- Seo S-C, "Aerosolization of particulate(1→3)-β-Dglucan from moldy materials", Applied and Environmental Microbiology, 74(3), pp.585~593 (2008)
- Seo S-C, "Sizefractionated(1→3)-β-D-glucan concentrations aerosolized from different moldy building materials", Science of The Total Environment, 407(2), pp.806~814 (2009)
- Heseltine E, "WHO guidelines for indoor air quality: dampness and mould", WHO Regional Office Europe, ~ (2009)
- Vesper S, "Traditional mould analysis compared to a DNA-based method of mould analysis", Critical Reviews in Microbiology, 37(1), pp.15~24 (2011)
- Vesper S, "Higher environmental relative moldiness index(ERMI)values measured in homes of asthmatic children in Boston, Kansas City, and San Diego", Journal of Asthma, 50(2), pp.155~161 (2013)
- Vesper S, "Quantitative PCR analysis of molds in the dust from homes of asthmatic children in North Carolina", Journal of Environmental Monitoring, 9(8), pp.826~830 (2007)
- Vesper S, "Correlation between ERMI values and other moisture and mold assessments of homes in the American Healthy Homes Survey", Journal of Urban Health, 86(6), pp.850~860 (2009)
- Vesper S, "Higher Environmental Relative Moldiness Index(ERMIsm)values measured in Detroit homes of severely asthmatic children", Science of the Total Environment, 394(1), pp.192~196 (2008)
- Vesper S, "Development of an environmental relative moldiness index for US homes", Journal of Occupational and Environmental Medicine, 49(8), pp.829~833 (2007)
- Vesper S, "Geographic distribution of Environmental Relative Moldiness Index molds in USA homes", Journal of Environmental and Public Health, 2011 (2011)
- Vesper S, "Comparison of populations of mould species in homes in the UK and USA using mould?specific quantitative PCR", Letters in applied microbiology, 41(4), pp.367~373 (2005)
- Vesper SJ, "Quantitative polymerase chain reaction analysis of fungi in dust from homes of infants who developed idiopathic pulmonary hemorrhaging", Journal of Occupational and Environmental Medicine, 46(6), pp.596~601 (2004)
- Täubel M, "Application of the environmental relative moldiness index in Finland", Applied and Environmental Microbiology, 82(2), pp.578~584 (2016)
- Méheust D, "Correlation between Environmental Relative Moldiness Index(ERMI)values in French dwellings and other measures of fungal contamination", Science of the Total Environment, 438, pp.319~324 (2012)
- Méheust D, "Possible application of the Environmental Relative Moldiness Index in France : A pilot study in Brittany", International Journal of Hygiene and Environmental Health, 216(3), pp.333~340 (2013)
- Lee J, "Establishment and Application of an Environmental Relative Moldiness Index for Dwellings in Korea", Indian Journal of Pharmaceutical Sciences, pp.78~85 (2020)
- Kim DH, "Prevalence and allergen of allergic rhinitis in Korean children", American Journal of Rhinology & Allergy, 30(3), pp.e72~e78 (2016)
- Verhoeff A, "Enumeration and identification of airborne viable mould propagules in houses : a field comparison of selected techniques", Allergy, 45(4), pp.275~284 (1990)
- 이정섭, "바닥 먼지내에서 DNA 기반 곰팡이 분석기법 개발", 한국산업보건학회지, 27(4), pp.324~332 (2017), 한국산업보건학회[DOI]
- 황은설, "공동주택의 계절별 부유곰팡이 농도 및 분포 현황", 한국생활환경학회지, 26(6), pp.825~833 (2019), 한국생활환경학회[DOI]
- Shelton BG, "Profiles of airborne fungi in buildings and outdoor environments in the United States", Applied and Environmental Microbiology, 68(4), pp.1743~1753 (2002)
- 허은혜, "실내공기 중 생물학적 오염물질에 관한 국내 연구 동향", 한국환경보건학회지, 38(4), pp.300~310 (2012), 한국환경보건학회[DOI]
- 송주희, "서울시 일부 종합병원의 공기 중 미생물 농도 분포", 한국환경보건학회지, 33(2), pp.104~114 (2007), 한국환경보건학회
- Oh H-J, "Characterization of indoor air quality and efficiency of air purifier in childcare centers, Korea", Building and Environment, 82, pp.203~214 (2014)
- 박재범, "다중이용시설 내부에 분포하는 부유 진균의 입경별 농도 특성", 한국환경보건학회지, 32(1), pp.36~45 (2006), 한국환경보건학회
- Studies on Indoor Mold Management (III), "Minstry of Environment RoK", ~ (2008)
- Studies on Indoor Mold Management (V), "Minstry of Environment RoK", ~ (2010)