Polyphenol, Flavonoid Contents and Anti-Inflammatory Active Effects of Rubus coreanus Miquel Extract
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In this study, we checked the antioxidant activity of the Rubus coreanus Miquel extract and measured the anti-inflammatory effect explore the possibility of using as a functional cosmetic material. Antioxidant activity was measured by total polyphenol and flavonoid contents, cell toxicity and Nitric oxide producing inhibitory effects in RAW 264.7 cells. This experiment performed at least three times under the same conditions. The statistical analysis of the mean ± standard deviation was performed using SPSS Windows Version 17.0, and the significance was tested by Student's t-test. As a result of the experiment, the total concentration-dependent polyphenol and total flavonoid contents were identified. In addition, a significant NO-producing inhibitory effect was confirmed, suggesting that the Rubus coreanus Miquel extract can be as a functional cosmetic material. With regard to cell cytotoxicity, no significant cellular toxicity was observed at all concentrations (10 to 100 μg/mL) of RAW 264.7 cells. Therefore, the Rubus coreanus Miquel extract showed that it has potential as a material for functional cosmetics
Abstract
In this study, we checked the antioxidant activity of the Rubus coreanus Miquel extract and measured the anti-inflammatory effect explore the possibility of using as a functional cosmetic material. Antioxidant activity was measured by total polyphenol and flavonoid contents, cell toxicity and Nitric oxide producing inhibitory effects in RAW 264.7 cells. This experiment performed at least three times under the same conditions. The statistical analysis of the mean ± standard deviation was performed using SPSS Windows Version 17.0, and the significance was tested by Student's t-test. As a result of the experiment, the total concentration-dependent polyphenol and total flavonoid contents were identified. In addition, a significant NO-producing inhibitory effect was confirmed, suggesting that the Rubus coreanus Miquel extract can be as a functional cosmetic material. With regard to cell cytotoxicity, no significant cellular toxicity was observed at all concentrations (10 to 100 μg/mL) of RAW 264.7 cells. Therefore, the Rubus coreanus Miquel extract showed that it has potential as a material for functional cosmetics
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