소아 수족구병 치료에 대한 은교산·곽박하령탕 병용 치료의 최신 임상 연구 동향: 중국 무작위 배정 임상연구를 중심으로

Abstract

Objectives This study aimed to evaluate the effects of Eungyo-san and Gwakbakharyung-tang on Hand, Foot, and Mouth diseases in children. Methods The Chinese National Knowledge Infrastructure was used to search for randomized controlled trials on Hand Foot and Mouth disease in children. Results We identified nine randomized controlled trials (RCTs) that investigated the use of Eungyo-san and Gwakbakharyung-tang, either alone or in combination with Western medicine, for the treatment of Hand, Foot, and Mouth Disease in children. These studies found this approach to be more effective than Western medicine alone. Conclusion Eungyo-san and Gwakbakharyung-tang may be effective against Hand, Foot, and Mouth disease in children. However, despite limitations such as insufficient reports of adverse events, the absence of well-designed randomized controlled trials in other countries, regional bias, limitations in the types of Western treatments used, and the small number of research subjects, this study remains meaningful. This study is significant because it analyzed RCTs conducted in China, focusing on the combination therapy of Eungyo-san and Gwakbakharyung-tang, thereby contributing to the establishment of an evidence base in this field